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Reviewed, UniProtKB/Swiss-Prot Q1RK99 (KGUA_RICBR)

Last modified December 15, 2009. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Guanylate kinase
    EC=2.7.4.8
Alternative name(s):
    GMP kinase
Gene names
Name: gmk
Ordered Locus Names: RBE_0134
OrganismRickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]
Taxonomic identifier336407 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsia

Protein attributes

Sequence length191 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Essential for recycling GMP and indirectly, cGMP By similarity.

Catalytic activity

ATP + GMP = ADP + GDP. HAMAP MF_00328

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the guanylate kinase family.

Contains 1 guanylate kinase-like domain.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processpurine nucleotide metabolic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: HAMAP

guanylate kinase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 191191Guanylate kinase HAMAP MF_00328
PRO_0000266388

Regions

Domain6 – 184179Guanylate kinase-like
Nucleotide binding13 – 208ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q1RK99-1 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: 627EEA3EA40099A1

FASTA19121,869
        10         20         30         40         50         60 
MTKNKGLIII LSSPSGAGKS SLAKALLEID HNLRLSISAT TRKPRPNEQD GVNYYFKTKV 

        70         80         90        100        110        120 
EFEKLVKQNQ FLEHAKIYDN YYGTPKKHVE NLLNQGLDVL FDIDWQGARS IKQNAVNAVS 

       130        140        150        160        170        180 
IFILPPNLEV LEQRLRNRAA DNEEAIQLRM ASAQAEISHS NEYDHIITND DFNDTIQQIH 

       190 
TIILQERKKR N 

« Hide

References

[1]"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
PLoS Genet. 2:733-744(2006) [PubMed: 16703114] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

CP000087 Genomic DNA. Translation: ABE04215.1.
RefSeqYP_537304.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ1RK99.

Genome annotation databases

GeneID3995234.
GenomeReviewsGene locus RBE_0134 in contig CP000087_GR.
KEGGrbe:RBE_0134.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG671982.
OMAEWAEFAG.

Enzyme and pathway databases

BioCycRBEL336407:RBE_0134-MON.

Family and domain databases

HAMAPMF_00328.
[Tree]
InterProIPR008144. Guanylate_kin.
IPR020590. Guanylate_kinase_CS.
IPR017665. Guanylate_kinase_sub.
IPR008145. Guanylt/Ca.
[Graphical view]
PfamPF00625. Guanylate_kin. 1 hit.
[Graphical view]
SMARTSM00072. GuKc. 1 hit.
[Graphical view]
PROSITEPS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameKGUA_RICBR
AccessionPrimary (citable) accession number: Q1RK99
Entry history
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: May 16, 2006
Last modified: December 15, 2009
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

Rickettsia bellii strain RML369-C

Rickettsia bellii (strain RML369-C): entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents