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Reviewed, UniProtKB/Swiss-Prot Q1RK92 (TLCE_RICBR)

Last modified November 24, 2009. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    ADP,ATP carrier protein 5
Alternative name(s):
    ADP/ATP translocase 5
Gene names
Name: tlcE
Synonyms: tlc5
Ordered Locus Names: RBE_0141
OrganismRickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]
Taxonomic identifier336407 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsia

Protein attributes

Sequence length500 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism By similarity.

Subcellular location

Cell membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the ADP/ATP translocase tlc family.

Ontologies

Keywords
   Biological processTransport
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
   LigandATP-binding
Nucleotide-binding
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processtransport

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

ATP:ADP antiporter activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 500500ADP,ATP carrier protein 5
PRO_0000286485

Regions

Transmembrane21 – 4121 Potential
Transmembrane62 – 8221 Potential
Transmembrane94 – 11421 Potential
Transmembrane149 – 16921 Potential
Transmembrane184 – 20421 Potential
Transmembrane224 – 24421 Potential
Transmembrane287 – 30721 Potential
Transmembrane328 – 34821 Potential
Transmembrane357 – 37721 Potential
Transmembrane381 – 40121 Potential
Transmembrane469 – 48921 Potential

Sequences

Sequence LengthMass (Da)Tools
Q1RK92-1 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: ED6D5604AD7BABF0

FASTA50057,123
        10         20         30         40         50         60 
MLSTSSSRPF KSKFRAAFWP IYNYELGKFI PMSALMFCIL FNQNILRILK DSILISEISA 

        70         80         90        100        110        120 
EIAGFAKVYC VTPAAALFVI IYAKMINHLT FEKIFYYLTA FFIGFFVLFA FVIYPNIHIF 

       130        140        150        160        170        180 
HVHPDYLADW MERYPHFKWY ISLIGNWGYI VYYSLAELWP NIFYVLLFWQ FANELTTTEE 

       190        200        210        220        230        240 
AKRFYTLFSL FGNSSLILVG FLMMNLSSKE TIVKHFINIS DSKITLVQIS TILVTIVAVI 

       250        260        270        280        290        300 
CCLLIRFISR NVFTNPLFYA KAKSGRSTSE RMGIIKSFKY IVKSKYLWLL LICSAAFGFA 

       310        320        330        340        350        360 
INLVEAVWKA KIKELYPTVN TYAEFNSLYI LWTGVAIMVM TIIGNNVMRM HNWFVAAVIS 

       370        380        390        400        410        420 
PVIIMVTGVL FFVLIVFDQK ILSLFDGAIL MSPLALAVSI GGIQNILAKG TKYSIWDTSR 

       430        440        450        460        470        480 
EMLYIPLDQE LKTKGKAAVD VISAKVGKSS SGLVQSIIFT IIPTATFTSI SPVLMVVFTF 

       490        500 
VCLAWIYAVR KIYFEYQKIA 

« Hide

References

[1]"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
PLoS Genet. 2:733-744(2006) [PubMed: 16703114] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

CP000087 Genomic DNA. Translation: ABE04222.1.
RefSeqYP_537311.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ1RK92.

Genome annotation databases

GeneID3995241.
GenomeReviewsGene locus RBE_0141 in contig CP000087_GR.
KEGGrbe:RBE_0141.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ1RK92.
OMAMMNLSSE

Enzyme and pathway databases

BioCycRBEL336407:RBE_0141-MON.

Family and domain databases

InterProIPR004667. ADP_ATP_car.
[Graphical view]
PfamPF03219. TLC. 1 hit.
[Graphical view]
TIGRFAMsTIGR00769. AAA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTLCE_RICBR
AccessionPrimary (citable) accession number: Q1RK92
Entry history
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: May 16, 2006
Last modified: November 24, 2009
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

Rickettsia bellii strain RML369-C

Rickettsia bellii (strain RML369-C): entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents