Reviewed, UniProtKB/Swiss-Prot Q1RK34 (LOLD_RICBR)

Names and origin

Protein names

Recommended name:
    Lipoprotein-releasing system ATP-binding protein lolD
    EC=3.6.3.-

Gene names

Name:	lolD
Ordered Locus Names:	RBE_0199

Organism

Rickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]

Taxonomic identifier

336407 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia

Protein attributes

Sequence length	221 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Part of the ABC transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, lolA. Responsible for the formation of the lolA-lipoprotein complex in an ATP-dependent manner By similarity.
Subunit structure	The complex is composed of two ATP-binding proteins (lolD) and two transmembrane proteins (lolC and lolE) Probable.
Subcellular location	Cell inner membrane; Peripheral membrane protein By similarity.
Sequence similarities	Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family. [View classification] Contains 1 ABC transporter domain.

Ontologies

Keywords
Biological process	Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Ligand	ATP-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipoprotein transport Inferred from electronic annotation. Source: HAMAP
Cellular component	extrinsic to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity Inferred from electronic annotation. Source: InterPro lipoprotein transporter activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 221	221	Lipoprotein-releasing system ATP-binding protein lolD HAMAP MF_01708		PRO_0000260196
Regions
	Domain	6 – 220	215	ABC transporter
	Nucleotide binding	42 – 49	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q1RK34-1 [UniParc]. Last modified May 16, 2006. Version 1. Checksum: 9A42322966D37002	FASTA	221	24,526
	10 20 30 40 50 60 MSNKILTLKN VSKHYRQGNS IIRVLDDLNL NINEGELIAI IGSSGSGKST LLHIAGLLDK 70 80 90 100 110 120 PTNGEVIIAN NEYKTNHLIR LNYLGFIYQQ HHLLKDFTAI ENVIMPRLIN GSNQKEAIEA 130 140 150 160 170 180 AKSILDSLGL GKKLHNMPGE LSGGEQQRVA IARSLINKPK IILADEPTGN LDPKTTNEVF 190 200 210 220 NLFLKVAKEQ NTAIVMVTHN HELAHRMDKL YKLKHGALNM S

References

[1]

"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens." Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D. PLoS Genet. 2:733-744(2006) [PubMed: 16703114] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000087 Genomic DNA. Translation: ABE04280.1.
RefSeq	YP_537369.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q1RK34.
Genome annotation databases
GeneID	3995343.
GenomeReviews	Gene locus RBE_0199 in contig CP000087_GR.
KEGG	rbe:RBE_0199.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q1RK34.
OMA	ELAHKMD
Enzyme and pathway databases
BioCyc	RBEL336407:RBE_0199-MON.
Family and domain databases
HAMAP	MF_01708. [Tree]
InterPro	IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR015854. ABC_transpr_LolD. IPR003593. ATPase_AAA+_core. [Graphical view]
Pfam	PF00005. ABC_tran. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
PROSITE	PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 1 hit. PS51244. LOLD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

LOLD_RICBR

Accession

Primary (citable) accession number: Q1RK34

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 28, 2006
Last sequence update:	May 16, 2006
Last modified:	November 24, 2009
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)