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Protein

Ribosomal large subunit pseudouridine synthase C

Gene

rluC

Organism
Rickettsia bellii (strain RML369-C)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA.By similarity

Catalytic activityi

23S rRNA uridine(955)/uridine(2504)/uridine(2580) = 23S rRNA pseudouridine(955)/pseudouridine(2504)/pseudouridine(2580).

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei140By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase, RNA-binding
Biological processrRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal large subunit pseudouridine synthase C (EC:5.4.99.24)
Alternative name(s):
23S rRNA pseudouridine(955/2504/2580) synthase
rRNA pseudouridylate synthase C
rRNA-uridine isomerase C
Gene namesi
Name:rluC
Ordered Locus Names:RBE_0256
OrganismiRickettsia bellii (strain RML369-C)
Taxonomic identifieri336407 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group
Proteomesi
  • UP000001951 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002866641 – 301Ribosomal large subunit pseudouridine synthase CAdd BLAST301

Structurei

3D structure databases

ProteinModelPortaliQ1RJX7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 70S4 RNA-bindingPROSITE-ProRule annotationAdd BLAST60

Sequence similaritiesi

Belongs to the pseudouridine synthase RluA family.Curated

Phylogenomic databases

HOGENOMiHOG000275914
KOiK06179
OMAiPKTHVYR
OrthoDBiPOG091H064O

Family and domain databases

CDDicd02869 PseudoU_synth_RluCD_like, 1 hit
cd00165 S4, 1 hit
Gene3Di3.10.290.10, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR006224 PsdUridine_synth_RluC/D_CS
IPR006145 PsdUridine_synth_RsuA/RluD
IPR002942 S4_RNA-bd
IPR036986 S4_RNA-bd_sf
PfamiView protein in Pfam
PF00849 PseudoU_synth_2, 1 hit
PF01479 S4, 1 hit
SMARTiView protein in SMART
SM00363 S4, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
PROSITEiView protein in PROSITE
PS01129 PSI_RLU, 1 hit
PS50889 S4, 1 hit

Sequencei

Sequence statusi: Complete.

Q1RJX7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIITVNSPIA SRLDKYLRRL YPLLTQGVIE KALRQKQIIV NSKKAEASLR
60 70 80 90 100
VVEGDEIFIH DKFNLPIAQP TKLVFTDAEI TLAKKITTEY LIYEDDNIIA
110 120 130 140 150
INKPAGLATQ GGSKINLSVD SALKYLNSQG ADFKLVHRLD KETSGLLLIA
160 170 180 190 200
KNYVSSVKLH DAFKEKLVEK TYLAVTYGKP IKDQGEVKTN IEKSKGSIPK
210 220 230 240 250
ITDINDNNGK LAITYYKLLK SLTNNLFLVE FIPITGRMHQ LRLHAKLLGC
260 270 280 290 300
PIFGDNKYGN DKLMPYSKYM FLHANNIVLS KKVFGKEVNL EAKLPSYFNR

V
Length:301
Mass (Da):33,932
Last modified:May 16, 2006 - v1
Checksum:i8B2751DF8A02902A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000087 Genomic DNA Translation: ABE04337.1
RefSeqiWP_011476949.1, NC_007940.1

Genome annotation databases

EnsemblBacteriaiABE04337; ABE04337; RBE_0256
KEGGirbe:RBE_0256

Similar proteinsi

Entry informationi

Entry nameiRLUC_RICBR
AccessioniPrimary (citable) accession number: Q1RJX7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: May 16, 2006
Last modified: April 25, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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