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Q1RJT5 (RF1_RICBR) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Peptide chain release factor 1

Short name=RF-1
Gene names
Name:prfA
Ordered Locus Names:RBE_0298
OrganismRickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]
Taxonomic identifier336407 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group

Protein attributes

Sequence length357 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA By similarity. HAMAP-Rule MF_00093

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00093.

Post-translational modification

Methylated by PrmC. Methylation increases the termination efficiency of RF1 By similarity. HAMAP-Rule MF_00093

Sequence similarities

Belongs to the prokaryotic/mitochondrial release factor family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   PTMMethylation
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functiontranslation release factor activity, codon specific

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 357357Peptide chain release factor 1 HAMAP-Rule MF_00093
PRO_0000263339

Amino acid modifications

Modified residue2361N5-methylglutamine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q1RJT5 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: 530AAD165D1027C8

FASTA35740,217
        10         20         30         40         50         60 
MNISSFSDNL TKILGKYEDL SEKLSSGIGG EEFVKASKEY ADLEDIVQKI KEYNKAKAEL 

        70         80         90        100        110        120 
EEANNFKQEP SLDKATLEMI EEEIRNLEDS LPTLERSVKI ALLPKDEADS KSAIIEIRAG 

       130        140        150        160        170        180 
TGGEEAALFA AKLFNMYQRY AELKGWRFEI LSIDETGIGG YKEVSASIKG KDVFSKLKFE 

       190        200        210        220        230        240 
SGVHRVQRVP ETESQGRIHT SAATVAVLPE VEDVDIKLEE KDLRIDTYRA SGAGGQHVNT 

       250        260        270        280        290        300 
TDSAVRITHI PTGITVALQD EKSQHKNKAK ALKILRARIY EEERRKKDQE RANNRRKQIG 

       310        320        330        340        350 
SGDRSERIRT YNFPQGRVSD HRINLTLYKI DEVINGQLDE FIEALIANDE AKKLSDI 

« Hide

References

[1]"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RML369-C.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000087 Genomic DNA. Translation: ABE04379.1.
RefSeqYP_537468.1. NC_007940.1.

3D structure databases

ProteinModelPortalQ1RJT5.
SMRQ1RJT5. Positions 104-355.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING336407.RBE_0298.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE04379; ABE04379; RBE_0298.
GeneID3996208.
KEGGrbe:RBE_0298.
PATRIC17881911. VBIRicBel102610_0335.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0216.
HOGENOMHOG000074815.
KOK02835.
OMAYGQLKFE.
OrthoDBEOG6TN48J.
ProtClustDBPRK00591.

Enzyme and pathway databases

BioCycRBEL336407:GJCY-304-MONOMER.

Family and domain databases

Gene3D3.30.160.20. 1 hit.
HAMAPMF_00093. Rel_fac_1.
InterProIPR014720. dsRNA-bd_dom.
IPR005139. PCRF.
IPR000352. Pep_chain_release_fac_I_II.
IPR004373. PrfA.
[Graphical view]
PfamPF03462. PCRF. 1 hit.
PF00472. RF-1. 1 hit.
[Graphical view]
SMARTSM00937. PCRF. 1 hit.
[Graphical view]
TIGRFAMsTIGR00019. prfA. 1 hit.
PROSITEPS00745. RF_PROK_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRF1_RICBR
AccessionPrimary (citable) accession number: Q1RJT5
Entry history
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: May 16, 2006
Last modified: February 19, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia bellii strain RML369-C

Rickettsia bellii (strain RML369-C): entries and gene names