Q1RJR7 (RADA_RICBR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DNA repair protein RadA homolog

Alternative name(s):
DNA repair protein Sms homolog

Gene names

Name:	radA
Ordered Locus Names:	RBE_0316

Organism

Rickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]

Taxonomic identifier

336407 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › belli group › Rickettsia bellii

Protein attributes

Sequence length	448 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May play a role in the repair of endogenous alkylation damage By similarity.
Sequence similarities	Belongs to the RecA family. RadA subfamily.

Ontologies

Keywords
Biological process	DNA damage DNA repair
Domain	Zinc-finger
Ligand	ATP-binding DNA-binding Metal-binding Nucleotide-binding Zinc
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA repair Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA-dependent ATPase activity Inferred from electronic annotation. Source: InterPro damaged DNA binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 448	448	DNA repair protein RadA homolog		PRO_0000286659
Regions
	Zinc finger	10 – 27	18	C4-type Potential
	Nucleotide binding	91 – 98	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q1RJR7 [UniParc]. Last modified May 16, 2006. Version 1. Checksum: D4F2DDDF1E82C3B8	FASTA	448	48,450
	10 20 30 40 50 60 MTKEKKHYIC SNCGNTSPKW SGQCFDCGVW GSIIEEKVIS NKNIAKIGSK QDFEQLSSNV 70 80 90 100 110 120 TDQVRISTPI GELDRVLGGG LVLGSAILIG GDPGIGKSTL LLQLVAGSFA SKVKCLYITG 130 140 150 160 170 180 EESLDQIKLR ALRLDLVNDK TNILAANNLE DIIASLEANK GNIDLVVIDS IQTIATRELT 190 200 210 220 230 240 SPPGTVSQIR TCAHELVNYA KQNNIIILLS CHVTKDGQLA GPKLLEHLVD TVLYFEGDHN 250 260 270 280 290 300 NHFRILRSYK NRFGGVGEIG VFEMSSSGLI EVTNPSELFL MKREQNVIGT AIFAGIEGSR 310 320 330 340 350 360 PLLMEVQALI VPSNMVTPRR SAVGWDVNRL SMILAVLSSR IGLNLANYEV YLSIAGGLKI 370 380 390 400 410 420 NEPASDLAVA ASLISAATNK PLPEHSVFFG EISLSGEIRK TAKAEARIKE ALKLGFNNII 430 440 CSKSENLTHD FISSIAHLKD LKLLLGSS

References

[1]

"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens." Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D. PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RML369-C.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000087 Genomic DNA. Translation: ABE04397.1.
RefSeq	YP_537486.1. NC_007940.1.
3D structure databases
ProteinModelPortal	Q1RJR7.
ModBase	Search...
Protein-protein interaction databases
STRING	336407.RBE_0316.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABE04397; ABE04397; RBE_0316.
GeneID	3996290.
KEGG	rbe:RBE_0316.
PATRIC	17881953. VBIRicBel102610_0356.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1066.
HOGENOM	HOG000218329.
KO	K04485.
OMA	SIQTLWS.
ProtClustDB	PRK11823.
Enzyme and pathway databases
BioCyc	RBEL336407:GJCY-322-MONOMER.
Family and domain databases
Gene3D	3.30.230.10. 1 hit.
InterPro	IPR003593. AAA+_ATPase. IPR020588. DNA_recomb_RecA/RadB_ATP-bd. IPR004504. DNA_repair_RadA. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. [Graphical view]
PANTHER	PTHR32472. PTHR32472. 1 hit.
PRINTS	PR01874. DNAREPAIRADA.
SMART	SM00382. AAA. 1 hit. [Graphical view]
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMs	TIGR00416. sms. 1 hit.
PROSITE	PS50162. RECA_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RADA_RICBR

Accession

Primary (citable) accession number: Q1RJR7

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 15, 2007
Last sequence update:	May 16, 2006
Last modified:	May 1, 2013
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program