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Q1RJR2

- Y321_RICBR

UniProt

Q1RJR2 - Y321_RICBR

Protein

Uncharacterized RNA pseudouridine synthase RBE_0321

Gene

RBE_0321

Organism
Rickettsia bellii (strain RML369-C)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 52 (01 Oct 2014)
      Sequence version 1 (16 May 2006)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    RNA uridine = RNA pseudouridine.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei102 – 1021NucleophileBy similarity

    GO - Molecular functioni

    1. pseudouridine synthase activity Source: InterPro
    2. RNA binding Source: UniProtKB-KW

    GO - Biological processi

    1. pseudouridine synthesis Source: InterPro

    Keywords - Molecular functioni

    Isomerase

    Keywords - Ligandi

    RNA-binding

    Enzyme and pathway databases

    BioCyciRBEL336407:GJCY-327-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized RNA pseudouridine synthase RBE_0321 (EC:5.4.99.-)
    Alternative name(s):
    RNA pseudouridylate synthase
    RNA-uridine isomerase
    Gene namesi
    Ordered Locus Names:RBE_0321
    OrganismiRickettsia bellii (strain RML369-C)
    Taxonomic identifieri336407 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group
    ProteomesiUP000001951: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 229229Uncharacterized RNA pseudouridine synthase RBE_0321PRO_0000294475Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi336407.RBE_0321.

    Structurei

    3D structure databases

    ProteinModelPortaliQ1RJR2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini2 – 6968S4 RNA-bindingPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the pseudouridine synthase RsuA family.Curated
    Contains 1 S4 RNA-binding domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG1187.
    HOGENOMiHOG000044954.
    KOiK06178.
    OMAiIRYGMLT.
    OrthoDBiEOG6130DV.

    Family and domain databases

    Gene3Di3.10.290.10. 1 hit.
    InterProiIPR020103. PsdUridine_synth_cat_dom.
    IPR000748. PsdUridine_synth_RsuA/RluB/E/F.
    IPR018496. PsdUridine_synth_RsuA/RluB_CS.
    IPR006145. PsdUridine_synth_RsuA/RluD.
    IPR002942. S4_RNA-bd.
    [Graphical view]
    PfamiPF00849. PseudoU_synth_2. 1 hit.
    PF01479. S4. 1 hit.
    [Graphical view]
    SMARTiSM00363. S4. 1 hit.
    [Graphical view]
    SUPFAMiSSF55120. SSF55120. 1 hit.
    TIGRFAMsiTIGR00093. TIGR00093. 1 hit.
    PROSITEiPS01149. PSI_RSU. 1 hit.
    PS50889. S4. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q1RJR2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQRLAKLISN AGICSRRDAE KLILDGQVKV NGIIVTSPAT NVDTDNQVEV    50
    SGSLITSSQK SRLWIYYKPV GLITTHKDPL SRKTVFEQLT GLPRVISIGR 100
    LDLNSEGLLL LTNNGDLARQ FELPSSKLKR VYHVRAYGNP DPLLKSNYKN 150
    LEIDGIFYNP QSIKLLRKNS TNSWLEVILF EGKNREIRRI FEHFGLKVNK 200
    LIRTEYGDFK LDNLKPNEYR EVTKKLYKC 229
    Length:229
    Mass (Da):26,222
    Last modified:May 16, 2006 - v1
    Checksum:i1864751558205D85
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000087 Genomic DNA. Translation: ABE04402.1.
    RefSeqiYP_537491.1. NC_007940.1.

    Genome annotation databases

    EnsemblBacteriaiABE04402; ABE04402; RBE_0321.
    GeneIDi3996295.
    KEGGirbe:RBE_0321.
    PATRICi17881963. VBIRicBel102610_0361.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000087 Genomic DNA. Translation: ABE04402.1 .
    RefSeqi YP_537491.1. NC_007940.1.

    3D structure databases

    ProteinModelPortali Q1RJR2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 336407.RBE_0321.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABE04402 ; ABE04402 ; RBE_0321 .
    GeneIDi 3996295.
    KEGGi rbe:RBE_0321.
    PATRICi 17881963. VBIRicBel102610_0361.

    Phylogenomic databases

    eggNOGi COG1187.
    HOGENOMi HOG000044954.
    KOi K06178.
    OMAi IRYGMLT.
    OrthoDBi EOG6130DV.

    Enzyme and pathway databases

    BioCyci RBEL336407:GJCY-327-MONOMER.

    Family and domain databases

    Gene3Di 3.10.290.10. 1 hit.
    InterProi IPR020103. PsdUridine_synth_cat_dom.
    IPR000748. PsdUridine_synth_RsuA/RluB/E/F.
    IPR018496. PsdUridine_synth_RsuA/RluB_CS.
    IPR006145. PsdUridine_synth_RsuA/RluD.
    IPR002942. S4_RNA-bd.
    [Graphical view ]
    Pfami PF00849. PseudoU_synth_2. 1 hit.
    PF01479. S4. 1 hit.
    [Graphical view ]
    SMARTi SM00363. S4. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55120. SSF55120. 1 hit.
    TIGRFAMsi TIGR00093. TIGR00093. 1 hit.
    PROSITEi PS01149. PSI_RSU. 1 hit.
    PS50889. S4. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
      Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
      PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: RML369-C.

    Entry informationi

    Entry nameiY321_RICBR
    AccessioniPrimary (citable) accession number: Q1RJR2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 10, 2007
    Last sequence update: May 16, 2006
    Last modified: October 1, 2014
    This is version 52 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia bellii strain RML369-C
      Rickettsia bellii (strain RML369-C): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3