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Protein

Uncharacterized RNA pseudouridine synthase RBE_0321

Gene

RBE_0321

Organism
Rickettsia bellii (strain RML369-C)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

RNA uridine = RNA pseudouridine.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei102 – 1021NucleophileBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Ligandi

RNA-binding

Enzyme and pathway databases

BioCyciRBEL336407:GJCY-327-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized RNA pseudouridine synthase RBE_0321 (EC:5.4.99.-)
Alternative name(s):
RNA pseudouridylate synthase
RNA-uridine isomerase
Gene namesi
Ordered Locus Names:RBE_0321
OrganismiRickettsia bellii (strain RML369-C)
Taxonomic identifieri336407 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group
ProteomesiUP000001951 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 229229Uncharacterized RNA pseudouridine synthase RBE_0321PRO_0000294475Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ1RJR2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 6968S4 RNA-bindingPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the pseudouridine synthase RsuA family.Curated
Contains 1 S4 RNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG1187.
HOGENOMiHOG000044954.
KOiK06178.
OMAiFAYKVTH.
OrthoDBiEOG6130DV.

Family and domain databases

Gene3Di3.10.290.10. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR000748. PsdUridine_synth_RsuA/RluB/E/F.
IPR018496. PsdUridine_synth_RsuA/RluB_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
IPR002942. S4_RNA-bd.
[Graphical view]
PfamiPF00849. PseudoU_synth_2. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
SMARTiSM00363. S4. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00093. TIGR00093. 1 hit.
PROSITEiPS01149. PSI_RSU. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1RJR2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQRLAKLISN AGICSRRDAE KLILDGQVKV NGIIVTSPAT NVDTDNQVEV
60 70 80 90 100
SGSLITSSQK SRLWIYYKPV GLITTHKDPL SRKTVFEQLT GLPRVISIGR
110 120 130 140 150
LDLNSEGLLL LTNNGDLARQ FELPSSKLKR VYHVRAYGNP DPLLKSNYKN
160 170 180 190 200
LEIDGIFYNP QSIKLLRKNS TNSWLEVILF EGKNREIRRI FEHFGLKVNK
210 220
LIRTEYGDFK LDNLKPNEYR EVTKKLYKC
Length:229
Mass (Da):26,222
Last modified:May 16, 2006 - v1
Checksum:i1864751558205D85
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000087 Genomic DNA. Translation: ABE04402.1.
RefSeqiWP_011477013.1. NC_007940.1.

Genome annotation databases

EnsemblBacteriaiABE04402; ABE04402; RBE_0321.
KEGGirbe:RBE_0321.
PATRICi17881963. VBIRicBel102610_0361.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000087 Genomic DNA. Translation: ABE04402.1.
RefSeqiWP_011477013.1. NC_007940.1.

3D structure databases

ProteinModelPortaliQ1RJR2.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABE04402; ABE04402; RBE_0321.
KEGGirbe:RBE_0321.
PATRICi17881963. VBIRicBel102610_0361.

Phylogenomic databases

eggNOGiCOG1187.
HOGENOMiHOG000044954.
KOiK06178.
OMAiFAYKVTH.
OrthoDBiEOG6130DV.

Enzyme and pathway databases

BioCyciRBEL336407:GJCY-327-MONOMER.

Family and domain databases

Gene3Di3.10.290.10. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR000748. PsdUridine_synth_RsuA/RluB/E/F.
IPR018496. PsdUridine_synth_RsuA/RluB_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
IPR002942. S4_RNA-bd.
[Graphical view]
PfamiPF00849. PseudoU_synth_2. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
SMARTiSM00363. S4. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00093. TIGR00093. 1 hit.
PROSITEiPS01149. PSI_RSU. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
    Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
    PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RML369-C.

Entry informationi

Entry nameiY321_RICBR
AccessioniPrimary (citable) accession number: Q1RJR2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: May 16, 2006
Last modified: July 22, 2015
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia bellii strain RML369-C
    Rickettsia bellii (strain RML369-C): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.