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Q1RJR2 (Y321_RICBR) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized RNA pseudouridine synthase RBE_0321

EC=5.4.99.-
Alternative name(s):
RNA pseudouridylate synthase
RNA-uridine isomerase
Gene names
Ordered Locus Names:RBE_0321
OrganismRickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]
Taxonomic identifier336407 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group

Protein attributes

Sequence length229 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

RNA uridine = RNA pseudouridine.

Sequence similarities

Belongs to the pseudouridine synthase RsuA family.

Contains 1 S4 RNA-binding domain.

Ontologies

Keywords
   LigandRNA-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpseudouridine synthesis

Inferred from electronic annotation. Source: InterPro

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

pseudouridine synthase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 229229Uncharacterized RNA pseudouridine synthase RBE_0321
PRO_0000294475

Regions

Domain2 – 6968S4 RNA-binding

Sites

Active site1021Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
Q1RJR2 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: 1864751558205D85

FASTA22926,222
        10         20         30         40         50         60 
MQRLAKLISN AGICSRRDAE KLILDGQVKV NGIIVTSPAT NVDTDNQVEV SGSLITSSQK 

        70         80         90        100        110        120 
SRLWIYYKPV GLITTHKDPL SRKTVFEQLT GLPRVISIGR LDLNSEGLLL LTNNGDLARQ 

       130        140        150        160        170        180 
FELPSSKLKR VYHVRAYGNP DPLLKSNYKN LEIDGIFYNP QSIKLLRKNS TNSWLEVILF 

       190        200        210        220 
EGKNREIRRI FEHFGLKVNK LIRTEYGDFK LDNLKPNEYR EVTKKLYKC 

« Hide

References

[1]"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RML369-C.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000087 Genomic DNA. Translation: ABE04402.1.
RefSeqYP_537491.1. NC_007940.1.

3D structure databases

ProteinModelPortalQ1RJR2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING336407.RBE_0321.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE04402; ABE04402; RBE_0321.
GeneID3996295.
KEGGrbe:RBE_0321.
PATRIC17881963. VBIRicBel102610_0361.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1187.
HOGENOMHOG000044954.
KOK06178.
OMAHVRAYGK.
OrthoDBEOG6130DV.
ProtClustDBCLSK870982.

Enzyme and pathway databases

BioCycRBEL336407:GJCY-327-MONOMER.

Family and domain databases

Gene3D3.10.290.10. 1 hit.
InterProIPR020103. PsdUridine_synth_cat_dom.
IPR000748. PsdUridine_synth_RsuA/RluB/E/F.
IPR018496. PsdUridine_synth_RsuA/RluB_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
IPR002942. S4_RNA-bd.
[Graphical view]
PfamPF00849. PseudoU_synth_2. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
SMARTSM00363. S4. 1 hit.
[Graphical view]
SUPFAMSSF55120. SSF55120. 1 hit.
TIGRFAMsTIGR00093. TIGR00093. 1 hit.
PROSITEPS01149. PSI_RSU. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameY321_RICBR
AccessionPrimary (citable) accession number: Q1RJR2
Entry history
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: May 16, 2006
Last modified: November 13, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia bellii strain RML369-C

Rickettsia bellii (strain RML369-C): entries and gene names