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Q1RJM0 (COAE_RICBR) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Dephospho-CoA kinase

EC=2.7.1.24
Alternative name(s):
Dephosphocoenzyme A kinase
Gene names
Name:coaE
Ordered Locus Names:RBE_0363
OrganismRickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]
Taxonomic identifier336407 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group

Protein attributes

Sequence length191 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A By similarity. HAMAP-Rule MF_00376

Catalytic activity

ATP + 3'-dephospho-CoA = ADP + CoA. HAMAP-Rule MF_00376

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 5/5. HAMAP-Rule MF_00376

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00376.

Sequence similarities

Belongs to the CoaE family.

Contains 1 DPCK (dephospho-CoA kinase) domain.

Ontologies

Keywords
   Biological processCoenzyme A biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcoenzyme A biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

dephospho-CoA kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 191191Dephospho-CoA kinase HAMAP-Rule MF_00376
PRO_0000243332

Regions

Domain3 – 191189DPCK
Nucleotide binding8 – 158ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q1RJM0 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: 0B1FF4C886738782

FASTA19122,020
        10         20         30         40         50         60 
MLAIGITGSY ASGKTFILDY LAEKGYKTFC ADRCIKELYQ DLKIQTGILK LLPELETFNI 

        70         80         90        100        110        120 
GKISNLIYNN DLAREKLQNF IYPLLIEKLI QFKQENVNSK FGFAEIPLLY EAKFDKYFDF 

       130        140        150        160        170        180 
VVTVHCSEEI RMQRATTRSS FDVEIYNKIK EIQLSQESKI AKADFAINSG VDMLDLEKQI 

       190 
NNLIANLECR V 

« Hide

References

[1]"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RML369-C.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000087 Genomic DNA. Translation: ABE04444.1.
RefSeqYP_537533.1. NC_007940.1.

3D structure databases

ProteinModelPortalQ1RJM0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING336407.RBE_0363.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE04444; ABE04444; RBE_0363.
GeneID3995034.
KEGGrbe:RBE_0363.
PATRIC17882061. VBIRicBel102610_0410.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0237.
HOGENOMHOG000010652.
KOK00859.
OMAHCSEEIR.
OrthoDBEOG6HTP3H.

Enzyme and pathway databases

BioCycRBEL336407:GJCY-369-MONOMER.
UniPathwayUPA00241; UER00356.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00376. Dephospho_CoA_kinase.
InterProIPR001977. Depp_CoAkinase.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF01121. CoaE. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00152. TIGR00152. 1 hit.
PROSITEPS51219. DPCK. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOAE_RICBR
AccessionPrimary (citable) accession number: Q1RJM0
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: May 16, 2006
Last modified: May 14, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia bellii strain RML369-C

Rickettsia bellii (strain RML369-C): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways