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Reviewed, UniProtKB/Swiss-Prot Q1RJI6 (NUOB_RICBR)

Last modified November 25, 2008. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    NADH-quinone oxidoreductase subunit B
    EC=1.6.99.5
Alternative name(s):
    NADH dehydrogenase I subunit B
    NDH-1 subunit B
Gene names
Name: nuoB
Ordered Locus Names: RBE_0397
OrganismRickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]
Taxonomic identifier336407 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsia

Protein attributes

Sequence length174 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient By similarity.

Catalytic activity

NADH + quinone = NAD(+) + quinol.

Cofactor

Binds 1 4Fe-4S cluster Potential.

Sequence similarities

Belongs to the complex I 20 kDa subunit family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 174174NADH-quinone oxidoreductase subunit B
PRO_0000287851

Sites

Metal binding471Iron-sulfur (4Fe-4S) Potential
Metal binding481Iron-sulfur (4Fe-4S) Potential
Metal binding1121Iron-sulfur (4Fe-4S) Potential
Metal binding1421Iron-sulfur (4Fe-4S) Potential

Sequences

Sequence LengthMass (Da)Tools
Q1RJI6-1 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: 39344EC7DB08A952

FASTA17419,633
        10         20         30         40         50         60 
MHNNFYQEDE LLNNELSNRG VLLTKVDDVI GWARSNSLWP MTFGLACCAV EMMQAAASRY 

        70         80         90        100        110        120 
DMDRFGMLFR PSPRQSDLMI VAGTLTNKMA PALRKVYDQM AEPKWVLSMG SCANGGGYYH 

       130        140        150        160        170 
FSYSVVRGCD RIVPVDVYVP GCPPTAEALI YGLMQLQKKI KRTTGFKYDA RKNH 

« Hide

References

[1]"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
PLoS Genet. 2:733-744(2006) [PubMed: 16703114] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

CP000087 Genomic DNA. Translation: ABE04478.1.
RefSeqYP_537567.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID3996175.
GenomeReviewsGene locus RBE_0397 in contig CP000087_GR.
KEGGrbe:RBE_0397.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ1RJI6.

Enzyme and pathway databases

BioCycRBEL336407:RBE_0397-MON.

Family and domain databases

InterProIPR006138. NADH_DHase_20kDa_su.
IPR014406. NiFe_hyd_3_ssu/Q_oxred_NuoB.
IPR006137. OxRdtase_q6.
[Graphical view]
PANTHERPTHR11995:SF2. NADH_DH_20kDa. 1 hit.
PTHR11995. NiFe_hyd_3_ssu/Q_oxred_NuoB. 1 hit.
PfamPF01058. Oxidored_q6. 1 hit.
[Graphical view]
TIGRFAMsTIGR01957. nuoB_fam. 1 hit.
PROSITEPS01150. COMPLEX1_20K. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNUOB_RICBR
AccessionPrimary (citable) accession number: Q1RJI6
Entry history
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: May 16, 2006
Last modified: November 25, 2008
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

Rickettsia bellii strain RML369-C

Rickettsia bellii (strain RML369-C): entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents