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Q1RJ84 (CLPX_RICBR) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
ATP-dependent Clp protease ATP-binding subunit ClpX
Gene names
Name:clpX
Ordered Locus Names:RBE_0499
OrganismRickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]
Taxonomic identifier336407 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group

Protein attributes

Sequence length427 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP By similarity. HAMAP-Rule MF_00175

Subunit structure

Heterodimer of ClpP and ClpX By similarity. HAMAP-Rule MF_00175

Sequence similarities

Belongs to the ClpX chaperone family.

Ontologies

Keywords
   DomainZinc-finger
   LigandATP-binding
Metal-binding
Nucleotide-binding
Zinc
   Molecular functionChaperone
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processprotein folding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

nucleoside-triphosphatase activity

Inferred from electronic annotation. Source: InterPro

zinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 427427ATP-dependent Clp protease ATP-binding subunit ClpX HAMAP-Rule MF_00175
PRO_0000277978

Regions

Zinc finger12 – 3726C4-type HAMAP-Rule MF_00175
Nucleotide binding116 – 1238ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q1RJ84 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: D3A44173941705BD

FASTA42746,882
        10         20         30         40         50         60 
MVVEANKKEL ICSFCSKKQH EVKKLIAGPA VFICDECINL CMDIMEEESK IALKQITYTI 

        70         80         90        100        110        120 
PTPQKICSVL NDYVVGQEQA KKVLAVAVYN HYKRLEYVQS GNNDVELNKS NILLIGPTGS 

       130        140        150        160        170        180 
GKTLLAQTLA KILDVPFTMA DATSLTEAGY VGEDVENILL RLLQAAEFNV AKAQKGIIYI 

       190        200        210        220        230        240 
DEVDKIARKS ENPSITRDVS GEGVQQALLK IMEGTVASVP PQGGRKHPQQ DFVQLDTSNI 

       250        260        270        280        290        300 
LFICGGAFMG IDSIITSRTN NSSIGFAANV NIDKEKINRE ILKSLEIEDL TKFGLIPEFI 

       310        320        330        340        350        360 
GRLPIVTTLD DLDKEALVTI LTKPKNAIVK QFKKQFELDE AELIVEDSAL EAIAEKALAK 

       370        380        390        400        410        420 
KTGARGLRSI IEHLLLDSMY KVAELKKQRV TITEDVVKGL IEPIITSIIT PTAKTSKKQA 


AVEDIPA 

« Hide

References

[1]"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RML369-C.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000087 Genomic DNA. Translation: ABE04580.1.
RefSeqYP_537669.1. NC_007940.1.

3D structure databases

ProteinModelPortalQ1RJ84.
SMRQ1RJ84. Positions 8-48.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING336407.RBE_0499.

Proteomic databases

PRIDEQ1RJ84.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE04580; ABE04580; RBE_0499.
GeneID3994912.
KEGGrbe:RBE_0499.
PATRIC17882396. VBIRicBel102610_0569.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1219.
HOGENOMHOG000010093.
KOK03544.
OMALDTMFDL.
OrthoDBEOG625JZK.
ProtClustDBPRK05342.

Enzyme and pathway databases

BioCycRBEL336407:GJCY-514-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 2 hits.
HAMAPMF_00175. ClpX.
InterProIPR003593. AAA+_ATPase.
IPR013093. ATPase_AAA-2.
IPR019489. Clp_ATPase_C.
IPR004487. Clp_protease_ATP-bd_su_ClpX.
IPR027417. P-loop_NTPase.
IPR010603. Znf_CppX_C4.
[Graphical view]
PANTHERPTHR11262:SF4. PTHR11262:SF4. 1 hit.
PfamPF07724. AAA_2. 1 hit.
PF10431. ClpB_D2-small. 1 hit.
PF06689. zf-C4_ClpX. 1 hit.
[Graphical view]
SMARTSM00382. AAA. 1 hit.
SM01086. ClpB_D2-small. 1 hit.
SM00994. zf-C4_ClpX. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00382. clpX. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCLPX_RICBR
AccessionPrimary (citable) accession number: Q1RJ84
Entry history
Integrated into UniProtKB/Swiss-Prot: February 20, 2007
Last sequence update: May 16, 2006
Last modified: April 16, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia bellii strain RML369-C

Rickettsia bellii (strain RML369-C): entries and gene names