Q1RJ71 (HSCB_RICBR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Co-chaperone protein HscB homolog

Gene names

Name:	hscB
Ordered Locus Names:	RBE_0512

Organism

Rickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]

Taxonomic identifier

336407 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › belli group › Rickettsia bellii

Protein attributes

Sequence length	166 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA By similarity. HAMAP-Rule MF_00682
Subunit structure	Interacts with HscA and stimulates its ATPase activity By similarity.
Sequence similarities	Belongs to the HscB family. Contains 1 J domain.

Ontologies

Keywords
Molecular function	Chaperone
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	protein folding Inferred from electronic annotation. Source: HAMAP protein oligomerization Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 166	166	Co-chaperone protein HscB homolog HAMAP-Rule MF_00682		PRO_0000286448
Regions
	Domain	3 – 73	71	J

Sequences

	Sequence		Length	Mass (Da)
	Q1RJ71 [UniParc]. Last modified May 16, 2006. Version 1. Checksum: A1AA7054AF3E7D5F	FASTA	166	19,670
	10 20 30 40 50 60 MQNYFELLGL EQIYNIDLKI LEKQYFAMQI KYHPDKAKNL QEKEQNLIIA SNLNKAYYTL 70 80 90 100 110 120 KDSLKRAEYM LLLYGVNLND EKVRSKLSAL ELSIFWDEME LIENTSSYKS LEEIKSKYEL 130 140 150 160 MEKAEVNFLA ESFKKQDLSD ATIKTSKLKY IHTLLSKLQE KMKLCK

References

[1]

"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens." Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D. PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RML369-C.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000087 Genomic DNA. Translation: ABE04593.1.
RefSeq	YP_537682.1. NC_007940.1.
3D structure databases
ProteinModelPortal	Q1RJ71.
ModBase	Search...
Protein-protein interaction databases
STRING	336407.RBE_0512.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABE04593; ABE04593; RBE_0512.
GeneID	3994925.
KEGG	rbe:RBE_0512.
PATRIC	17882426. VBIRicBel102610_0584.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1076.
HOGENOM	HOG000063516.
KO	K04082.
OMA	SKLKYIR.
ProtClustDB	PRK01356.
Enzyme and pathway databases
BioCyc	RBEL336407:GJCY-527-MONOMER.
Family and domain databases
Gene3D	1.10.287.110. 1 hit. 1.20.1280.20. 1 hit.
HAMAP	MF_00682. HscB.
InterPro	IPR001623. DnaJ_domain. IPR004640. HscB. IPR009073. HscB_oligo_C. [Graphical view]
PANTHER	PTHR14021. PTHR14021. 1 hit.
Pfam	PF00226. DnaJ. 1 hit. PF07743. HSCB_C. 1 hit. [Graphical view]
SMART	SM00271. DnaJ. 1 hit. [Graphical view]
SUPFAM	SSF46565. DnaJ_N. 1 hit. SSF47144. HSC20_C. 1 hit.
TIGRFAMs	TIGR00714. hscB. 1 hit.
PROSITE	PS00636. DNAJ_1. False negative. PS50076. DNAJ_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HSCB_RICBR

Accession

Primary (citable) accession number: Q1RJ71

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 15, 2007
Last sequence update:	May 16, 2006
Last modified:	May 1, 2013
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program