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Protein

60 kDa chaperonin

Gene

groL

Organism
Rickettsia bellii (strain RML369-C)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation
Ordered Locus Names:RBE_0590
OrganismiRickettsia bellii (strain RML369-C)
Taxonomic identifieri336407 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group
Proteomesi
  • UP000001951 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002569761 – 55060 kDa chaperoninAdd BLAST550

Proteomic databases

PRIDEiQ1RIZ3

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ1RIZ3
SMRiQ1RIZ3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000076290
KOiK04077
OMAiTDTDKME
OrthoDBiPOG091H00E7

Family and domain databases

CDDicd03344 GroEL, 1 hit
Gene3Di1.10.560.10, 2 hits
3.30.260.10, 2 hits
3.50.7.10, 1 hit
HAMAPiMF_00600 CH60, 1 hit
InterProiView protein in InterPro
IPR018370 Chaperonin_Cpn60_CS
IPR001844 Chaprnin_Cpn60
IPR002423 Cpn60/TCP-1
IPR027409 GroEL-like_apical_dom_sf
IPR027413 GROEL-like_equatorial_sf
IPR027410 TCP-1-like_intermed_sf
PfamiView protein in Pfam
PF00118 Cpn60_TCP1, 1 hit
PRINTSiPR00298 CHAPERONIN60
SUPFAMiSSF48592 SSF48592, 2 hits
SSF52029 SSF52029, 1 hit
SSF54849 SSF54849, 1 hit
TIGRFAMsiTIGR02348 GroEL, 1 hit
PROSITEiView protein in PROSITE
PS00296 CHAPERONINS_CPN60, 1 hit

Sequencei

Sequence statusi: Complete.

Q1RIZ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATKLIKHGS KAREQMLEGI DILADAVKVT LGPKGRNVLI EQSFGAPKIT
60 70 80 90 100
KDGVTVAKSI ELKDKIRNAG AQLLKSAATK AAEVAGDGTT TATVLARALA
110 120 130 140 150
REGNKLVAAG YNPMDLKRGM DLAVNTVLEE VKKASKKIDS QEEIAQVGTI
160 170 180 190 200
SSNGDKEIGE KIAKAMEEVG KEGVITVEEA KNFSFDVEVV KGMMFDRGYL
210 220 230 240 250
SPYFVTNSEK MVAELENPYI LLFEKKLSNL QPMLPILEAV VQSQRPLLII
260 270 280 290 300
AEDVEGEALA TLVVNRLRGG LKVAAVKAPG FGDRRKAMME DIAILTNGEL
310 320 330 340 350
ITEDLGMKLE NVSLKSLGHA KRVTISKENT VIVDGSGDKK NIEERVLQIK
360 370 380 390 400
SHIAETTSDY DKEKLQERLA KLSGGVAVLK VGGATEVEVK ERKDRVEDAL
410 420 430 440 450
AATRAAVEEG VVAGGGVTLL HASQALKNLK VDNKDQQAGI ELVIEALKDP
460 470 480 490 500
IKQIVENAGE NGGVVVGKLL EHKDKNFGFN AQDMQYVDMI KAGIIDPAKV
510 520 530 540 550
VRTALQDAAS VASLIITTET LIVDEPEDKE NPMPMRGGMG GMGGMGGMDF
Length:550
Mass (Da):58,947
Last modified:May 16, 2006 - v1
Checksum:i1EB9FC3E5EE8E50A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000087 Genomic DNA Translation: ABE04671.1
RefSeqiWP_011477259.1, NC_007940.1

Genome annotation databases

EnsemblBacteriaiABE04671; ABE04671; RBE_0590
KEGGirbe:RBE_0590

Similar proteinsi

Entry informationi

Entry nameiCH60_RICBR
AccessioniPrimary (citable) accession number: Q1RIZ3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: May 16, 2006
Last modified: May 23, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Rickettsia bellii strain RML369-C
    Rickettsia bellii (strain RML369-C): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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