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Q1RIZ3 (CH60_RICBR) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
60 kDa chaperonin
Alternative name(s):
GroEL protein
Protein Cpn60
Gene names
Name:groL
Synonyms:groEL
Ordered Locus Names:RBE_0590
OrganismRickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]
Taxonomic identifier336407 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › belli group ›

Protein attributes

Sequence length550 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions By similarity. HAMAP-Rule MF_00600

Subunit structure

Oligomer of 14 subunits composed of two stacked rings of 7 subunits By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00600.

Sequence similarities

Belongs to the chaperonin (HSP60) family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionChaperone
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processprotein refolding

Inferred from electronic annotation. Source: HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 55055060 kDa chaperonin HAMAP-Rule MF_00600
PRO_0000256976

Sequences

Sequence LengthMass (Da)Tools
Q1RIZ3 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: 1EB9FC3E5EE8E50A

FASTA55058,947
        10         20         30         40         50         60 
MATKLIKHGS KAREQMLEGI DILADAVKVT LGPKGRNVLI EQSFGAPKIT KDGVTVAKSI 

        70         80         90        100        110        120 
ELKDKIRNAG AQLLKSAATK AAEVAGDGTT TATVLARALA REGNKLVAAG YNPMDLKRGM 

       130        140        150        160        170        180 
DLAVNTVLEE VKKASKKIDS QEEIAQVGTI SSNGDKEIGE KIAKAMEEVG KEGVITVEEA 

       190        200        210        220        230        240 
KNFSFDVEVV KGMMFDRGYL SPYFVTNSEK MVAELENPYI LLFEKKLSNL QPMLPILEAV 

       250        260        270        280        290        300 
VQSQRPLLII AEDVEGEALA TLVVNRLRGG LKVAAVKAPG FGDRRKAMME DIAILTNGEL 

       310        320        330        340        350        360 
ITEDLGMKLE NVSLKSLGHA KRVTISKENT VIVDGSGDKK NIEERVLQIK SHIAETTSDY 

       370        380        390        400        410        420 
DKEKLQERLA KLSGGVAVLK VGGATEVEVK ERKDRVEDAL AATRAAVEEG VVAGGGVTLL 

       430        440        450        460        470        480 
HASQALKNLK VDNKDQQAGI ELVIEALKDP IKQIVENAGE NGGVVVGKLL EHKDKNFGFN 

       490        500        510        520        530        540 
AQDMQYVDMI KAGIIDPAKV VRTALQDAAS VASLIITTET LIVDEPEDKE NPMPMRGGMG 

       550 
GMGGMGGMDF

« Hide

References

[1]"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RML369-C.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000087 Genomic DNA. Translation: ABE04671.1.
RefSeqYP_537760.1. NC_007940.1.

3D structure databases

ProteinModelPortalQ1RIZ3.
SMRQ1RIZ3. Positions 2-526.
ModBaseSearch...

Protein-protein interaction databases

STRING336407.RBE_0590.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE04671; ABE04671; RBE_0590.
GeneID3996030.
KEGGrbe:RBE_0590.
PATRIC17882611. VBIRicBel102610_0675.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0459.
HOGENOMHOG000076290.
KOK04077.
OMAAGDAKNI.
ProtClustDBPRK00013.

Enzyme and pathway databases

BioCycRBEL336407:GJCY-606-MONOMER.

Family and domain databases

Gene3D1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPMF_00600. CH60.
InterProIPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
[Graphical view]
PANTHERPTHR11353. PTHR11353. 1 hit.
PfamPF00118. Cpn60_TCP1. 1 hit.
[Graphical view]
PRINTSPR00298. CHAPERONIN60.
SUPFAMSSF48592. GroEL-ATPase. 1 hit.
SSF52029. SSF52029. 1 hit.
TIGRFAMsTIGR02348. GroEL. 1 hit.
PROSITEPS00296. CHAPERONINS_CPN60. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCH60_RICBR
AccessionPrimary (citable) accession number: Q1RIZ3
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: May 16, 2006
Last modified: May 29, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Rickettsia bellii strain RML369-C

Rickettsia bellii (strain RML369-C): entries and gene names

SIMILARITY comments

Index of protein domains and families

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