SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q1RIN5

- CCME_RICBR

UniProt

Q1RIN5 - CCME_RICBR

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Cytochrome c-type biogenesis protein CcmE

Gene
ccmE, cycJ, RBE_0698
Organism
Rickettsia bellii (strain RML369-C)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei120 – 1201Heme (covalent; via pros nitrogen) By similarity
Metal bindingi124 – 1241Iron (heme axial ligand) By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. cytochrome complex assembly Source: UniProtKB-KW
  2. protein-heme linkage Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

Cytochrome c-type biogenesis

Keywords - Ligandi

Heme, Iron, Metal-binding

Enzyme and pathway databases

BioCyciRBEL336407:GJCY-719-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c-type biogenesis protein CcmE
Alternative name(s):
Cytochrome c maturation protein E
Heme chaperone CcmE
Gene namesi
Name:ccmE
Synonyms:cycJ
Ordered Locus Names:RBE_0698
OrganismiRickettsia bellii (strain RML369-C)
Taxonomic identifieri336407 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group
ProteomesiUP000001951: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 88Cytoplasmic Reviewed prediction
Transmembranei9 – 2921Helical; Signal-anchor for type II membrane protein; Reviewed predictionAdd
BLAST
Topological domaini30 – 137108Periplasmic Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 137137Cytochrome c-type biogenesis protein CcmEUniRule annotationPRO_0000272364Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi336407.RBE_0698.

Structurei

3D structure databases

ProteinModelPortaliQ1RIN5.

Family & Domainsi

Sequence similaritiesi

Belongs to the CcmE/CycJ family.

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG2332.
HOGENOMiHOG000009661.
KOiK02197.
OMAiENYMPRE.
OrthoDBiEOG69D3JN.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_01959. CcmE.
InterProiIPR004329. CcmE.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF03100. CcmE. 1 hit.
[Graphical view]
SUPFAMiSSF82093. SSF82093. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1RIN5-1 [UniParc]FASTAAdd to Basket

« Hide

MQKGAKNRLI TIIICFCSAV IGVSIILYNL EKSIVFFVPP SKINEVEQGK    50
ELRVGGLVKV DSINKIAADK ISFVITDNIK DLEIFYQGVL PALFRENQGI 100
IAIGRLSNGK FIARELLAKH DENYRPPNTV IPAKAGI 137
Length:137
Mass (Da):15,124
Last modified:May 16, 2006 - v1
Checksum:i5FC0FC3DF53E10AD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000087 Genomic DNA. Translation: ABE04779.1.
RefSeqiYP_537868.1. NC_007940.1.

Genome annotation databases

EnsemblBacteriaiABE04779; ABE04779; RBE_0698.
GeneIDi3995409.
KEGGirbe:RBE_0698.
PATRICi17882872. VBIRicBel102610_0801.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000087 Genomic DNA. Translation: ABE04779.1 .
RefSeqi YP_537868.1. NC_007940.1.

3D structure databases

ProteinModelPortali Q1RIN5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 336407.RBE_0698.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABE04779 ; ABE04779 ; RBE_0698 .
GeneIDi 3995409.
KEGGi rbe:RBE_0698.
PATRICi 17882872. VBIRicBel102610_0801.

Phylogenomic databases

eggNOGi COG2332.
HOGENOMi HOG000009661.
KOi K02197.
OMAi ENYMPRE.
OrthoDBi EOG69D3JN.

Enzyme and pathway databases

BioCyci RBEL336407:GJCY-719-MONOMER.

Family and domain databases

Gene3Di 2.40.50.140. 1 hit.
HAMAPi MF_01959. CcmE.
InterProi IPR004329. CcmE.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF03100. CcmE. 1 hit.
[Graphical view ]
SUPFAMi SSF82093. SSF82093. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
    Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
    PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RML369-C.

Entry informationi

Entry nameiCCME_RICBR
AccessioniPrimary (citable) accession number: Q1RIN5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: May 16, 2006
Last modified: May 14, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia bellii strain RML369-C
    Rickettsia bellii (strain RML369-C): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi