ID   CAPD_RICBR              Reviewed;         341 AA.
AC   Q1RIM4;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2006, sequence version 1.
DT   16-JUN-2009, entry version 25.
DE   RecName: Full=UDP-glucose 4-epimerase;
DE            EC=5.1.3.2;
DE   AltName: Full=UDP-galactose 4-epimerase;
DE   AltName: Full=Galactowaldenase;
GN   Name=capD; OrderedLocusNames=RBE_0709;
OS   Rickettsia bellii (strain RML369-C).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia.
OX   NCBI_TaxID=336407;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16703114; DOI=10.1371/journal.pgen.0020076;
RA   Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C.,
RA   Fournier P.-E., Claverie J.-M., Raoult D.;
RT   "Genome sequence of Rickettsia bellii illuminates the role of amoebae
RT   in gene exchanges between intracellular pathogens.";
RL   PLoS Genet. 2:733-744(2006).
CC   -!- FUNCTION: Epimerizes UDP-galactose to UDP-glucose (By similarity).
CC   -!- CATALYTIC ACTIVITY: UDP-glucose = UDP-galactose.
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000087; ABE04790.1; -; Genomic_DNA.
DR   RefSeq; YP_537879.1; -.
DR   GeneID; 3995309; -.
DR   GenomeReviews; CP000087_GR; RBE_0709.
DR   KEGG; rbe:RBE_0709; -.
DR   HOGENOM; Q1RIM4; -.
DR   OMA; Q1RIM4; GDIFVQK.
DR   BioCyc; RBEL336407:RBE_0709-MON; -.
DR   GO; GO:0005488; F:binding; IEA:InterPro.
DR   GO; GO:0003978; F:UDP-glucose 4-epimerase activity; IEA:EC.
DR   GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   InterPro; IPR003869; Polysac_CapD-like.
DR   InterPro; IPR013692; Polysac_syn_C.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   PANTHER; PTHR10366:SF23; Polysac_CapD; 1.
DR   Pfam; PF08485; Polysacc_syn_2C; 1.
DR   Pfam; PF02719; Polysacc_synt_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Isomerase; Lipopolysaccharide biosynthesis.
FT   CHAIN         1    341       UDP-glucose 4-epimerase.
FT                                /FTId=PRO_0000314601.
SQ   SEQUENCE   341 AA;  38596 MW;  E27CD38C3C5E9FA2 CRC64;
     MFVDKTLLIT GGTGSFGNAV LSRFLKNDII KDIKEIRIFS RDEKKQEDMR IALNNPKIKF
     YIGDVRNYNS IDDAMKGVDY VFHAAALKQV PTCEFYPMEA INTNILGAEN VLRAATINKV
     AKVIVLSTDK AVYPINAMGL SKALMEKLAI AKARMNVRDK TVFCVTRYGN VMASRGSVIP
     LFINQIKQNK DLTITEPSMT RFLMSLVDSV DLVLYAFEYG HQGDIFVQKS PASTIEVLAK
     ALQGIFNSKN KIRFIGTRHG EKHYESLVSS EEMAKAEDLG NYYRIPMDGR DLNYAKYFVE
     GEKKIALLED YTSHNTKRLN LEEVKELLLN LDYVQEELKN A
//