Q1RIM4 (CAPD_RICBR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
UDP-glucose 4-epimerase
EC=5.1.3.2

Alternative name(s):
Galactowaldenase
UDP-galactose 4-epimerase

Gene names

Name:	capD
Ordered Locus Names:	RBE_0709

Organism

Rickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]

Taxonomic identifier

336407 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia

Protein attributes

Sequence length	341 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Epimerizes UDP-galactose to UDP-glucose By similarity.
Catalytic activity	UDP-glucose = UDP-galactose.
Sequence similarities	Belongs to the polysaccharide synthase family.

Ontologies

Keywords
Biological process	Lipopolysaccharide biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipopolysaccharide biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	UDP-glucose 4-epimerase activity Inferred from electronic annotation. Source: EC nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 341	341	UDP-glucose 4-epimerase		PRO_0000314601

Sequences

	Sequence		Length	Mass (Da)
	Q1RIM4 [UniParc]. Last modified May 16, 2006. Version 1. Checksum: E27CD38C3C5E9FA2	FASTA	341	38,596
	10 20 30 40 50 60 MFVDKTLLIT GGTGSFGNAV LSRFLKNDII KDIKEIRIFS RDEKKQEDMR IALNNPKIKF 70 80 90 100 110 120 YIGDVRNYNS IDDAMKGVDY VFHAAALKQV PTCEFYPMEA INTNILGAEN VLRAATINKV 130 140 150 160 170 180 AKVIVLSTDK AVYPINAMGL SKALMEKLAI AKARMNVRDK TVFCVTRYGN VMASRGSVIP 190 200 210 220 230 240 LFINQIKQNK DLTITEPSMT RFLMSLVDSV DLVLYAFEYG HQGDIFVQKS PASTIEVLAK 250 260 270 280 290 300 ALQGIFNSKN KIRFIGTRHG EKHYESLVSS EEMAKAEDLG NYYRIPMDGR DLNYAKYFVE 310 320 330 340 GEKKIALLED YTSHNTKRLN LEEVKELLLN LDYVQEELKN A

References

[1]

"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens." Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D. PLoS Genet. 2:733-744(2006) [PubMed: 16703114] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RML369-C.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000087 Genomic DNA. Translation: ABE04790.1.
RefSeq	YP_537879.1. NC_007940.1.
3D structure databases
ProteinModelPortal	Q1RIM4.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1RIM4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3995309.
GenomeReviews	Gene locus RBE_0709 in contig CP000087_GR.
KEGG	rbe:RBE_0709.
PATRIC	17882896. VBIRicBel102610_0813.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1086.
HOGENOM	HBG429349.
OMA	LNYAKYF.
ProtClustDB	CLSK870330.
Enzyme and pathway databases
BioCyc	RBEL336407:RBE_0709-MONOMER.
Family and domain databases
InterPro	IPR016040. NAD(P)-bd_dom. IPR003869. Polysac_CapD-like. IPR013692. Polysac_syn_C. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
Pfam	PF08485. Polysacc_syn_2C. 1 hit. PF02719. Polysacc_synt_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CAPD_RICBR

Accession

Primary (citable) accession number: Q1RIM4

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	May 16, 2006
Last modified:	January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program