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Q1RII7

- CDSA_RICBR

UniProt

Q1RII7 - CDSA_RICBR

Protein

Phosphatidate cytidylyltransferase

Gene

cdsA

Organism
Rickettsia bellii (strain RML369-C)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (16 May 2006)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    CTP + phosphatidate = diphosphate + CDP-diacylglycerol.

    Pathwayi

    GO - Molecular functioni

    1. phosphatidate cytidylyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. CDP-diacylglycerol biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Nucleotidyltransferase, Transferase

    Keywords - Biological processi

    Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

    Enzyme and pathway databases

    BioCyciRBEL336407:GJCY-767-MONOMER.
    UniPathwayiUPA00557; UER00614.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphatidate cytidylyltransferase (EC:2.7.7.41)
    Alternative name(s):
    CDP-DAG synthase
    CDP-DG synthase
    CDP-diacylglycerol synthase
    Short name:
    CDS
    CDP-diglyceride pyrophosphorylase
    CDP-diglyceride synthase
    CTP:phosphatidate cytidylyltransferase
    Gene namesi
    Name:cdsA
    Ordered Locus Names:RBE_0746
    OrganismiRickettsia bellii (strain RML369-C)
    Taxonomic identifieri336407 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group
    ProteomesiUP000001951: Chromosome

    Subcellular locationi

    Cell membrane By similarity; Multi-pass membrane protein By similarity

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 231231Phosphatidate cytidylyltransferasePRO_0000281056Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi336407.RBE_0746.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei33 – 5321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei67 – 8721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei95 – 11521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei133 – 15321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei167 – 18721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei206 – 22621HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the CDS family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0575.
    HOGENOMiHOG000006169.
    KOiK00981.
    OMAiKTWSGLI.
    OrthoDBiEOG6TBHJT.

    Family and domain databases

    InterProiIPR000374. PC_trans.
    [Graphical view]
    PfamiPF01148. CTP_transf_1. 1 hit.
    [Graphical view]
    PROSITEiPS01315. CDS. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q1RII7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIIQKGKEHL AKDKQKSNLY LRILSGIVLV PSFVVAILWL KPLFYVLMIL    50
    VAIGMLSEWY DMTHSSIMYL LIGLIIIPIP ISLLIFLSSN PINNWLIMLY 100
    FCIVWSVDIF AMIGGKTLGG AKLAPKISPK KTWSGLITGI LSAGLVATLI 150
    SFIPSFYIEN YYFSNRIYLF IISCTLALTA QLSDLFISYF KRKFNIKDSG 200
    NIIPGHGGVL DRFDSIILTA PILFFINGLY L 231
    Length:231
    Mass (Da):25,953
    Last modified:May 16, 2006 - v1
    Checksum:i271C1A453FA649F2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000087 Genomic DNA. Translation: ABE04827.1.
    RefSeqiWP_011477414.1. NC_007940.1.
    YP_537916.1. NC_007940.1.

    Genome annotation databases

    EnsemblBacteriaiABE04827; ABE04827; RBE_0746.
    GeneIDi3995428.
    KEGGirbe:RBE_0746.
    PATRICi17882981. VBIRicBel102610_0855.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000087 Genomic DNA. Translation: ABE04827.1 .
    RefSeqi WP_011477414.1. NC_007940.1.
    YP_537916.1. NC_007940.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 336407.RBE_0746.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABE04827 ; ABE04827 ; RBE_0746 .
    GeneIDi 3995428.
    KEGGi rbe:RBE_0746.
    PATRICi 17882981. VBIRicBel102610_0855.

    Phylogenomic databases

    eggNOGi COG0575.
    HOGENOMi HOG000006169.
    KOi K00981.
    OMAi KTWSGLI.
    OrthoDBi EOG6TBHJT.

    Enzyme and pathway databases

    UniPathwayi UPA00557 ; UER00614 .
    BioCyci RBEL336407:GJCY-767-MONOMER.

    Family and domain databases

    InterProi IPR000374. PC_trans.
    [Graphical view ]
    Pfami PF01148. CTP_transf_1. 1 hit.
    [Graphical view ]
    PROSITEi PS01315. CDS. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
      Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
      PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: RML369-C.

    Entry informationi

    Entry nameiCDSA_RICBR
    AccessioniPrimary (citable) accession number: Q1RII7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 20, 2007
    Last sequence update: May 16, 2006
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. Rickettsia bellii strain RML369-C
      Rickettsia bellii (strain RML369-C): entries and gene names
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3