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Q1RIG2 (TRUB_RICBR) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
tRNA pseudouridine synthase B

EC=5.4.99.25
Alternative name(s):
tRNA pseudouridine(55) synthase
Short name=Psi55 synthase
tRNA pseudouridylate synthase
tRNA-uridine isomerase
Gene names
Name:truB
Ordered Locus Names:RBE_0771
OrganismRickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]
Taxonomic identifier336407 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group

Protein attributes

Sequence length293 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs By similarity. HAMAP-Rule MF_01080

Catalytic activity

tRNA uridine55 = tRNA pseudouridine55. HAMAP-Rule MF_01080

Sequence similarities

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.

Ontologies

Keywords
   Biological processtRNA processing
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtRNA pseudouridine synthesis

Inferred from electronic annotation. Source: HAMAP

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: InterPro

pseudouridine synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 293293tRNA pseudouridine synthase B HAMAP-Rule MF_01080
PRO_0000277928

Sites

Active site391Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
Q1RIG2 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: DE166573D0ED7EE0

FASTA29332,926
        10         20         30         40         50         60 
MNSYWLNVYK PRGISSAKLV SIIKKVLGKV KIGHSGTLDV EAEGVLPLAI GEATKLVQML 

        70         80         90        100        110        120 
IDAKKTYIFT VKFGKQTDSG DYAGKVIAIT DYIPSKENAY AICSKFIGTI TQIPPAFSAL 

       130        140        150        160        170        180 
KVNGVRAYKL ARDGKEVELK PRNITIYDLK CLNYDEQNAT ATYYAECSKG TYIRTLAEDL 

       190        200        210        220        230        240 
ALSLQSLGFV IELRRTQVGI FKEENSIRID SFNDITKLSL EEKNIKIEAI LDDILVLDAN 

       250        260        270        280        290 
DEQAQKIKYG QKCLFDYDKN VDFMWVRYKG VLLTIGSLNK NCFHSLRVFN LTQ 

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References

[1]"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RML369-C.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000087 Genomic DNA. Translation: ABE04852.1.
RefSeqYP_537941.1. NC_007940.1.

3D structure databases

ProteinModelPortalQ1RIG2.
ModBaseSearch...

Protein-protein interaction databases

STRING336407.RBE_0771.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE04852; ABE04852; RBE_0771.
GeneID3995485.
KEGGrbe:RBE_0771.
PATRIC17883031. VBIRicBel102610_0880.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0130.
HOGENOMHOG000231225.
KOK03177.
OMAYRFHIAW.
ProtClustDBPRK01528.

Enzyme and pathway databases

BioCycRBEL336407:GJCY-792-MONOMER.

Family and domain databases

HAMAPMF_01080. TruB_bact.
InterProIPR002501. PsdUridine_synth.
IPR020103. PsdUridine_synth_cat_dom.
IPR014780. tRNA_psdUridine_synth_TruB.
[Graphical view]
PANTHERPTHR13767. PTHR13767. 1 hit.
PfamPF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMSSF55120. PsdUridine_synth_cat_dom. 1 hit.
TIGRFAMsTIGR00431. TruB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTRUB_RICBR
AccessionPrimary (citable) accession number: Q1RIG2
Entry history
Integrated into UniProtKB/Swiss-Prot: February 20, 2007
Last sequence update: May 16, 2006
Last modified: May 1, 2013
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Rickettsia bellii strain RML369-C

Rickettsia bellii (strain RML369-C): entries and gene names

SIMILARITY comments

Index of protein domains and families