Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q1RIC9

- SYP_RICBR

UniProt

Q1RIC9 - SYP_RICBR

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Proline--tRNA ligase

Gene

proS

Organism
Rickettsia bellii (strain RML369-C)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).UniRule annotation

Catalytic activityi

ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. proline-tRNA ligase activity Source: UniProtKB-EC

GO - Biological processi

  1. prolyl-tRNA aminoacylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciRBEL336407:GJCY-826-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Proline--tRNA ligaseUniRule annotation (EC:6.1.1.15UniRule annotation)
Alternative name(s):
Prolyl-tRNA synthetaseUniRule annotation
Short name:
ProRSUniRule annotation
Gene namesi
Name:proSUniRule annotation
Ordered Locus Names:RBE_0804
OrganismiRickettsia bellii (strain RML369-C)
Taxonomic identifieri336407 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group
ProteomesiUP000001951: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 432432Proline--tRNA ligasePRO_0000248914Add
BLAST

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi336407.RBE_0804.

Structurei

3D structure databases

ProteinModelPortaliQ1RIC9.
SMRiQ1RIC9. Positions 1-420.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0442.
HOGENOMiHOG000076894.
KOiK01881.
OMAiCDTIEKL.
OrthoDBiEOG6TTVMR.

Family and domain databases

Gene3Di3.40.50.800. 1 hit.
HAMAPiMF_01570. Pro_tRNA_synth_type2.
InterProiIPR002314. aa-tRNA-synt_IIb_cons-dom.
IPR006195. aa-tRNA-synth_II.
IPR004154. Anticodon-bd.
IPR002316. Pro-tRNA-ligase_IIa.
IPR004500. Pro-tRNA-synth_IIa_bac-type.
IPR023716. Prolyl-tRNA_ligase_IIa_type2.
[Graphical view]
PfamiPF03129. HGTP_anticodon. 1 hit.
PF00587. tRNA-synt_2b. 1 hit.
[Graphical view]
PRINTSiPR01046. TRNASYNTHPRO.
SUPFAMiSSF52954. SSF52954. 1 hit.
TIGRFAMsiTIGR00409. proS_fam_II. 1 hit.
PROSITEiPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1RIC9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLLSKYFLPV LKEDPSEAQI TSHKLMLRSG MIRQQAAGIY SWLPLGLKVL
60 70 80 90 100
KNIENIVRSN MDKAGCLEVL MPCIQPAHLW VESGRFDNYG KEMLKFQDRH
110 120 130 140 150
DNTLLFGPTN EDMVTDIFRN NIKSYKDLPK NLYHIQWKFR DEIRPRFGVM
160 170 180 190 200
RGREFLMKDA YSFDIDEESA VKTYNQMYKA YINTFRDLGV FAVPVIADNG
210 220 230 240 250
PIGGKLSHEF HIIAETGESN IYYDKRFKTL KDNPDIDIEE IKSWYAAAEE
260 270 280 290 300
KHDASKLSSD KEITSSKGIE VGHIFYIGTK YSVNMNALIN DEHGKLTPIE
310 320 330 340 350
MSSYGIGISR LVAAIIEANS DAKGIIWPIA VAPFKISLIN LNIHDSKCLE
360 370 380 390 400
LAERVYNELL AQNIEVLYDD TDVRAGSKFA THDLIGSPYQ IIIGPKKAAN
410 420 430
NIVELKNRKN GEIEDIDLNK RALNSYLTFF NS
Length:432
Mass (Da):49,206
Last modified:May 16, 2006 - v1
Checksum:iF86E21AA57A6B3FA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000087 Genomic DNA. Translation: ABE04885.1.
RefSeqiYP_537974.1. NC_007940.1.

Genome annotation databases

EnsemblBacteriaiABE04885; ABE04885; RBE_0804.
GeneIDi3996267.
KEGGirbe:RBE_0804.
PATRICi17883107. VBIRicBel102610_0917.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000087 Genomic DNA. Translation: ABE04885.1 .
RefSeqi YP_537974.1. NC_007940.1.

3D structure databases

ProteinModelPortali Q1RIC9.
SMRi Q1RIC9. Positions 1-420.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 336407.RBE_0804.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABE04885 ; ABE04885 ; RBE_0804 .
GeneIDi 3996267.
KEGGi rbe:RBE_0804.
PATRICi 17883107. VBIRicBel102610_0917.

Phylogenomic databases

eggNOGi COG0442.
HOGENOMi HOG000076894.
KOi K01881.
OMAi CDTIEKL.
OrthoDBi EOG6TTVMR.

Enzyme and pathway databases

BioCyci RBEL336407:GJCY-826-MONOMER.

Family and domain databases

Gene3Di 3.40.50.800. 1 hit.
HAMAPi MF_01570. Pro_tRNA_synth_type2.
InterProi IPR002314. aa-tRNA-synt_IIb_cons-dom.
IPR006195. aa-tRNA-synth_II.
IPR004154. Anticodon-bd.
IPR002316. Pro-tRNA-ligase_IIa.
IPR004500. Pro-tRNA-synth_IIa_bac-type.
IPR023716. Prolyl-tRNA_ligase_IIa_type2.
[Graphical view ]
Pfami PF03129. HGTP_anticodon. 1 hit.
PF00587. tRNA-synt_2b. 1 hit.
[Graphical view ]
PRINTSi PR01046. TRNASYNTHPRO.
SUPFAMi SSF52954. SSF52954. 1 hit.
TIGRFAMsi TIGR00409. proS_fam_II. 1 hit.
PROSITEi PS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
    Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
    PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RML369-C.

Entry informationi

Entry nameiSYP_RICBR
AccessioniPrimary (citable) accession number: Q1RIC9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: May 16, 2006
Last modified: October 29, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. Rickettsia bellii strain RML369-C
    Rickettsia bellii (strain RML369-C): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3