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Q1RI93

- COXX_RICBR

UniProt

Q1RI93 - COXX_RICBR

Protein

Protoheme IX farnesyltransferase

Gene

ctaB

Organism
Rickettsia bellii (strain RML369-C)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (16 May 2006)
      Previous versions | rss
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    Functioni

    Converts protoheme IX and farnesyl diphosphate to heme O.By similarity

    Pathwayi

    GO - Molecular functioni

    1. protoheme IX farnesyltransferase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. heme O biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    Heme biosynthesis

    Enzyme and pathway databases

    BioCyciRBEL336407:GJCY-862-MONOMER.
    UniPathwayiUPA00834; UER00712.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protoheme IX farnesyltransferaseUniRule annotation (EC:2.5.1.-UniRule annotation)
    Alternative name(s):
    Heme O synthaseUniRule annotation
    Gene namesi
    Name:ctaBUniRule annotation
    Ordered Locus Names:RBE_0840
    OrganismiRickettsia bellii (strain RML369-C)
    Taxonomic identifieri336407 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group
    ProteomesiUP000001951: Chromosome

    Subcellular locationi

    Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 300300Protoheme IX farnesyltransferasePRO_0000274892Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi336407.RBE_0840.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei31 – 5121HelicalUniRule annotationAdd
    BLAST
    Transmembranei52 – 7221HelicalUniRule annotationAdd
    BLAST
    Transmembranei92 – 11221HelicalUniRule annotationAdd
    BLAST
    Transmembranei123 – 14523HelicalUniRule annotationAdd
    BLAST
    Transmembranei152 – 17221HelicalUniRule annotationAdd
    BLAST
    Transmembranei179 – 19921HelicalUniRule annotationAdd
    BLAST
    Transmembranei225 – 24521HelicalUniRule annotationAdd
    BLAST
    Transmembranei247 – 26721HelicalUniRule annotationAdd
    BLAST
    Transmembranei280 – 30021HelicalUniRule annotationAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the UbiA prenyltransferase family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0109.
    HOGENOMiHOG000237291.
    KOiK02301.
    OMAiFKYSIGY.
    OrthoDBiEOG6DVJQB.

    Family and domain databases

    HAMAPiMF_00154. CyoE_CtaB.
    InterProiIPR006369. Protohaem_IX_farnesylTrfase.
    IPR000537. UbiA_prenyltransferase.
    [Graphical view]
    PfamiPF01040. UbiA. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01473. cyoE_ctaB. 1 hit.
    PROSITEiPS00943. UBIA. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q1RI93-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNSLTKSINL DKVSYPQSTV KDYILLMKPR VMSLVVFTGF SGMWLAPNSL    50
    HPFISVIALI CIAIGAGSAG AINMWYDRDI DALMKRTQKR PIVRGAIEAD 100
    EALSFGLIMA FFSVFFMALC VNFLSALLLL FTIFYYICIY TMWLKRSSIQ 150
    NIVIGGAAGA LPPVIGYASV SGSVSLDSVI LFLIIFIWTP PHSWALALFC 200
    NDDYKNCKVP MMPVIKGALY TKKQILIYSV LLFLTSLKPF FVGMSNIIYL 250
    VIAAVLGLVF LYYSISLFYD NADNKQAKRF FAYSIFYLFF IFLLLDFCRV 300
    Length:300
    Mass (Da):33,748
    Last modified:May 16, 2006 - v1
    Checksum:iAB1F8546D86ECB68
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000087 Genomic DNA. Translation: ABE04921.1.
    RefSeqiYP_538010.1. NC_007940.1.

    Genome annotation databases

    EnsemblBacteriaiABE04921; ABE04921; RBE_0840.
    GeneIDi3995135.
    KEGGirbe:RBE_0840.
    PATRICi17883185. VBIRicBel102610_0956.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000087 Genomic DNA. Translation: ABE04921.1 .
    RefSeqi YP_538010.1. NC_007940.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 336407.RBE_0840.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABE04921 ; ABE04921 ; RBE_0840 .
    GeneIDi 3995135.
    KEGGi rbe:RBE_0840.
    PATRICi 17883185. VBIRicBel102610_0956.

    Phylogenomic databases

    eggNOGi COG0109.
    HOGENOMi HOG000237291.
    KOi K02301.
    OMAi FKYSIGY.
    OrthoDBi EOG6DVJQB.

    Enzyme and pathway databases

    UniPathwayi UPA00834 ; UER00712 .
    BioCyci RBEL336407:GJCY-862-MONOMER.

    Family and domain databases

    HAMAPi MF_00154. CyoE_CtaB.
    InterProi IPR006369. Protohaem_IX_farnesylTrfase.
    IPR000537. UbiA_prenyltransferase.
    [Graphical view ]
    Pfami PF01040. UbiA. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01473. cyoE_ctaB. 1 hit.
    PROSITEi PS00943. UBIA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
      Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
      PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: RML369-C.

    Entry informationi

    Entry nameiCOXX_RICBR
    AccessioniPrimary (citable) accession number: Q1RI93
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 6, 2007
    Last sequence update: May 16, 2006
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. Rickettsia bellii strain RML369-C
      Rickettsia bellii (strain RML369-C): entries and gene names
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3