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Q1RI36

- SECA_RICBR

UniProt

Q1RI36 - SECA_RICBR

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Protein

Protein translocase subunit SecA

Gene
secA, RBE_0897
Organism
Rickettsia bellii (strain RML369-C)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane By similarity.UniRule annotation

Cofactori

May bind 1 zinc ion per subunit Reviewed prediction.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi894 – 8941Zinc Reviewed prediction
Metal bindingi896 – 8961Zinc Reviewed prediction
Metal bindingi905 – 9051Zinc Reviewed prediction
Metal bindingi906 – 9061Zinc Reviewed prediction

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi101 – 1088ATP Reviewed prediction

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. intracellular protein transmembrane transport Source: UniProtKB-HAMAP
  2. protein import Source: InterPro
  3. protein targeting Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

Protein transport, Translocation, Transport

Keywords - Ligandi

ATP-binding, Metal-binding, Nucleotide-binding, Zinc

Enzyme and pathway databases

BioCyciRBEL336407:GJCY-919-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein translocase subunit SecA
Gene namesi
Name:secA
Ordered Locus Names:RBE_0897
OrganismiRickettsia bellii (strain RML369-C)
Taxonomic identifieri336407 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group
ProteomesiUP000001951: Chromosome

Subcellular locationi

Cell inner membrane; Peripheral membrane protein; Cytoplasmic side By similarity. Cytoplasm By similarity
Note: Distribution is 50-50 By similarity.UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Cytoplasm, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 910910Protein translocase subunit SecAUniRule annotationPRO_0000277299Add
BLAST

Interactioni

Subunit structurei

Monomer and homodimer By similarity. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi336407.RBE_0897.

Structurei

3D structure databases

ProteinModelPortaliQ1RI36.
SMRiQ1RI36. Positions 13-231.

Family & Domainsi

Sequence similaritiesi

Belongs to the SecA family.

Phylogenomic databases

eggNOGiCOG0653.
HOGENOMiHOG000218168.
KOiK03070.
OMAiEAYEFQQ.
OrthoDBiEOG654P48.

Family and domain databases

Gene3Di1.10.3060.10. 1 hit.
3.40.50.300. 3 hits.
3.90.1440.10. 1 hit.
HAMAPiMF_01382. SecA.
InterProiIPR027417. P-loop_NTPase.
IPR004027. SEC_C_motif.
IPR000185. SecA.
IPR020937. SecA_CS.
IPR011115. SecA_DEAD.
IPR014018. SecA_motor_DEAD.
IPR011130. SecA_preprotein_X-link_dom.
IPR011116. SecA_Wing/Scaffold.
[Graphical view]
PfamiPF02810. SEC-C. 1 hit.
PF07517. SecA_DEAD. 1 hit.
PF01043. SecA_PP_bind. 1 hit.
PF07516. SecA_SW. 1 hit.
[Graphical view]
PRINTSiPR00906. SECA.
SMARTiSM00957. SecA_DEAD. 1 hit.
SM00958. SecA_PP_bind. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 3 hits.
SSF81767. SSF81767. 1 hit.
SSF81886. SSF81886. 2 hits.
TIGRFAMsiTIGR00963. secA. 1 hit.
PROSITEiPS01312. SECA. 1 hit.
PS51196. SECA_MOTOR_DEAD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1RI36-1 [UniParc]FASTAAdd to Basket

« Hide

MFSILKKIFG TANDRTIKKL FSDIAKINSL EPAIQKLSDE ELKNKTVEFK    50
KKLKNGATLD DIAYEAFAVV REASRRVYGM RHFDVQLIGG LVLHRGMITE 100
MRTGEGKTLV ATLPAYLNAL AEKGVHVVTV NDYLVSRDSA SMGKIYNFLG 150
LSVGCIVAGM TDEAKREAYN SDITYATNNE LGFDYLRDNM KYSLQERVLR 200
PFNFAIIDEV DSILIDEART PLVISGPVND NSELYGKVDK LVRMLNVSDF 250
EKDEKLKTIN LTESGISHVE SLLSQADIIK PNSGLYDFEN LSLVHYVNQA 300
LRAHNMFMID VDYLVRDGKV MIIDEFTGRV MEGRRYSEGL HQALEAKENV 350
KIQNENQTLA SITFQNYFRN YPKLSGMTGT AMTEAPELKD IYNLDVVAVP 400
THNKVTRRDL DDEIYGSKKE KYDAILKLIK DCYDRGQPVL VGTVSIEKSE 450
EISNVLNKNK IPHKVLNAKF HEQEAFIIAQ AGRFKAVTIA TNMAGRGTDI 500
MLGGNPEMLI EQIDRKSLTN AAYKEKVNEI KAQTAEEKKQ VIAAGGLFVI 550
GTERHESRRI DNQLRGRSGR QGDPGNTKFF LSLDDDLMRI FASERISGVL 600
RTLGLKDGEA IHHPMISRSL EKAQQKVEGH NYEIRKNLLR FDDVMNDQRK 650
IIYEQRTEII KSKDSYDFLS STTEELAKKI VLTFMPAGSY REDWDIENLS 700
VELHRTFAIK LDQNLISKND VTEEEVTKIV IQTADSIYKS KEEAYSPDLM 750
HNAVKYILLT TLDQVWKDHL HSLDHLRQGI SLRAYAQKDP LSEYKREAFN 800
LFEHMLNNLK ELFIQTVYHF HIDLKHIQKE DISLENKKLQ NNMHESREDP 850
AFSKYNAGSN LETDLRPVIS RINPEDRDPK NPTSWGKVSR NELCPCGSGK 900
KYKYCHGLNE 910
Length:910
Mass (Da):103,716
Last modified:May 16, 2006 - v1
Checksum:iC4FD4D044614D91F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000087 Genomic DNA. Translation: ABE04978.1.
RefSeqiYP_538067.1. NC_007940.1.

Genome annotation databases

EnsemblBacteriaiABE04978; ABE04978; RBE_0897.
GeneIDi3995264.
KEGGirbe:RBE_0897.
PATRICi17883315. VBIRicBel102610_1021.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000087 Genomic DNA. Translation: ABE04978.1 .
RefSeqi YP_538067.1. NC_007940.1.

3D structure databases

ProteinModelPortali Q1RI36.
SMRi Q1RI36. Positions 13-231.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 336407.RBE_0897.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABE04978 ; ABE04978 ; RBE_0897 .
GeneIDi 3995264.
KEGGi rbe:RBE_0897.
PATRICi 17883315. VBIRicBel102610_1021.

Phylogenomic databases

eggNOGi COG0653.
HOGENOMi HOG000218168.
KOi K03070.
OMAi EAYEFQQ.
OrthoDBi EOG654P48.

Enzyme and pathway databases

BioCyci RBEL336407:GJCY-919-MONOMER.

Family and domain databases

Gene3Di 1.10.3060.10. 1 hit.
3.40.50.300. 3 hits.
3.90.1440.10. 1 hit.
HAMAPi MF_01382. SecA.
InterProi IPR027417. P-loop_NTPase.
IPR004027. SEC_C_motif.
IPR000185. SecA.
IPR020937. SecA_CS.
IPR011115. SecA_DEAD.
IPR014018. SecA_motor_DEAD.
IPR011130. SecA_preprotein_X-link_dom.
IPR011116. SecA_Wing/Scaffold.
[Graphical view ]
Pfami PF02810. SEC-C. 1 hit.
PF07517. SecA_DEAD. 1 hit.
PF01043. SecA_PP_bind. 1 hit.
PF07516. SecA_SW. 1 hit.
[Graphical view ]
PRINTSi PR00906. SECA.
SMARTi SM00957. SecA_DEAD. 1 hit.
SM00958. SecA_PP_bind. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 3 hits.
SSF81767. SSF81767. 1 hit.
SSF81886. SSF81886. 2 hits.
TIGRFAMsi TIGR00963. secA. 1 hit.
PROSITEi PS01312. SECA. 1 hit.
PS51196. SECA_MOTOR_DEAD. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
    Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
    PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RML369-C.

Entry informationi

Entry nameiSECA_RICBR
AccessioniPrimary (citable) accession number: Q1RI36
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: May 16, 2006
Last modified: May 14, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia bellii strain RML369-C
    Rickettsia bellii (strain RML369-C): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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