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Q1RI36 (SECA_RICBR) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein translocase subunit SecA
Gene names
Name:secA
Ordered Locus Names:RBE_0897
OrganismRickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]
Taxonomic identifier336407 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group

Protein attributes

Sequence length910 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane By similarity. HAMAP-Rule MF_01382

Cofactor

May bind 1 zinc ion per subunit Potential.

Subunit structure

Monomer and homodimer By similarity. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC By similarity. HAMAP-Rule MF_01382

Subcellular location

Cell inner membrane; Peripheral membrane protein; Cytoplasmic side By similarity. Cytoplasm By similarity. Note: Distribution is 50-50 By similarity. HAMAP-Rule MF_01382

Sequence similarities

Belongs to the SecA family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 910910Protein translocase subunit SecA HAMAP-Rule MF_01382
PRO_0000277299

Regions

Nucleotide binding101 – 1088ATP Potential

Sites

Metal binding8941Zinc Potential
Metal binding8961Zinc Potential
Metal binding9051Zinc Potential
Metal binding9061Zinc Potential

Sequences

Sequence LengthMass (Da)Tools
Q1RI36 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: C4FD4D044614D91F

FASTA910103,716
        10         20         30         40         50         60 
MFSILKKIFG TANDRTIKKL FSDIAKINSL EPAIQKLSDE ELKNKTVEFK KKLKNGATLD 

        70         80         90        100        110        120 
DIAYEAFAVV REASRRVYGM RHFDVQLIGG LVLHRGMITE MRTGEGKTLV ATLPAYLNAL 

       130        140        150        160        170        180 
AEKGVHVVTV NDYLVSRDSA SMGKIYNFLG LSVGCIVAGM TDEAKREAYN SDITYATNNE 

       190        200        210        220        230        240 
LGFDYLRDNM KYSLQERVLR PFNFAIIDEV DSILIDEART PLVISGPVND NSELYGKVDK 

       250        260        270        280        290        300 
LVRMLNVSDF EKDEKLKTIN LTESGISHVE SLLSQADIIK PNSGLYDFEN LSLVHYVNQA 

       310        320        330        340        350        360 
LRAHNMFMID VDYLVRDGKV MIIDEFTGRV MEGRRYSEGL HQALEAKENV KIQNENQTLA 

       370        380        390        400        410        420 
SITFQNYFRN YPKLSGMTGT AMTEAPELKD IYNLDVVAVP THNKVTRRDL DDEIYGSKKE 

       430        440        450        460        470        480 
KYDAILKLIK DCYDRGQPVL VGTVSIEKSE EISNVLNKNK IPHKVLNAKF HEQEAFIIAQ 

       490        500        510        520        530        540 
AGRFKAVTIA TNMAGRGTDI MLGGNPEMLI EQIDRKSLTN AAYKEKVNEI KAQTAEEKKQ 

       550        560        570        580        590        600 
VIAAGGLFVI GTERHESRRI DNQLRGRSGR QGDPGNTKFF LSLDDDLMRI FASERISGVL 

       610        620        630        640        650        660 
RTLGLKDGEA IHHPMISRSL EKAQQKVEGH NYEIRKNLLR FDDVMNDQRK IIYEQRTEII 

       670        680        690        700        710        720 
KSKDSYDFLS STTEELAKKI VLTFMPAGSY REDWDIENLS VELHRTFAIK LDQNLISKND 

       730        740        750        760        770        780 
VTEEEVTKIV IQTADSIYKS KEEAYSPDLM HNAVKYILLT TLDQVWKDHL HSLDHLRQGI 

       790        800        810        820        830        840 
SLRAYAQKDP LSEYKREAFN LFEHMLNNLK ELFIQTVYHF HIDLKHIQKE DISLENKKLQ 

       850        860        870        880        890        900 
NNMHESREDP AFSKYNAGSN LETDLRPVIS RINPEDRDPK NPTSWGKVSR NELCPCGSGK 

       910 
KYKYCHGLNE 

« Hide

References

[1]"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RML369-C.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000087 Genomic DNA. Translation: ABE04978.1.
RefSeqYP_538067.1. NC_007940.1.

3D structure databases

ProteinModelPortalQ1RI36.
SMRQ1RI36. Positions 13-231.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING336407.RBE_0897.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE04978; ABE04978; RBE_0897.
GeneID3995264.
KEGGrbe:RBE_0897.
PATRIC17883315. VBIRicBel102610_1021.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0653.
HOGENOMHOG000218168.
KOK03070.
OMAEAYEFQQ.
OrthoDBEOG654P48.

Enzyme and pathway databases

BioCycRBEL336407:GJCY-919-MONOMER.

Family and domain databases

Gene3D1.10.3060.10. 1 hit.
3.40.50.300. 3 hits.
3.90.1440.10. 1 hit.
HAMAPMF_01382. SecA.
InterProIPR027417. P-loop_NTPase.
IPR004027. SEC_C_motif.
IPR000185. SecA.
IPR020937. SecA_CS.
IPR011115. SecA_DEAD.
IPR014018. SecA_motor_DEAD.
IPR011130. SecA_preprotein_X-link_dom.
IPR011116. SecA_Wing/Scaffold.
[Graphical view]
PfamPF02810. SEC-C. 1 hit.
PF07517. SecA_DEAD. 1 hit.
PF01043. SecA_PP_bind. 1 hit.
PF07516. SecA_SW. 1 hit.
[Graphical view]
PRINTSPR00906. SECA.
SMARTSM00957. SecA_DEAD. 1 hit.
SM00958. SecA_PP_bind. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 3 hits.
SSF81767. SSF81767. 1 hit.
SSF81886. SSF81886. 2 hits.
TIGRFAMsTIGR00963. secA. 1 hit.
PROSITEPS01312. SECA. 1 hit.
PS51196. SECA_MOTOR_DEAD. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSECA_RICBR
AccessionPrimary (citable) accession number: Q1RI36
Entry history
Integrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: May 16, 2006
Last modified: May 14, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia bellii strain RML369-C

Rickettsia bellii (strain RML369-C): entries and gene names