Q1RI35 (PLP_RICBR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Parvulin-like PPIase
EC=5.2.1.8

Alternative name(s):
Peptidyl-prolyl cis-trans isomerase plp
Rotamase plp

Gene names

Name:	plp
Ordered Locus Names:	RBE_0898

Organism

Rickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]

Taxonomic identifier

336407 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › belli group › Rickettsia bellii

Protein attributes

Sequence length	284 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Peptidylproline (omega=180) = peptidylproline (omega=0).
Subcellular location	Cell outer membrane By similarity.
Sequence similarities	Belongs to the PpiC/parvulin rotamase family. Contains 1 PpiC domain.

Ontologies

Keywords
Cellular component	Cell membrane Cell outer membrane Membrane
Domain	Signal
Molecular function	Isomerase Rotamase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	protein folding Inferred from electronic annotation. Source: UniProtKB-KW protein peptidyl-prolyl isomerization Inferred from electronic annotation. Source: GOC
Cellular_component	cell outer membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	peptidyl-prolyl cis-trans isomerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 20	20	Potential
	Chain	21 – 284	264	Parvulin-like PPIase		PRO_0000289284
Regions
	Domain	139 – 232	94	PpiC

Sequences

	Sequence		Length	Mass (Da)
	Q1RI35 [UniParc]. Last modified May 16, 2006. Version 1. Checksum: 4D33940EA0421305	FASTA	284	31,790
	10 20 30 40 50 60 MKKLSIVLLS VSMLSSIAFA DNSDRVVATY TGGEVRESQI MKEFKPQLNL PSGETIKNFD 70 80 90 100 110 120 DFPPQDQDKL IRIYVNNILL KKEVEKSNIT SSKEFQEKLE NAKNQLAQKE LLENYVKSNL 130 140 150 160 170 180 TDKMFDDEYN KYVTSLKGKE QIKVAHILVK SEKEANDLKN KLNKGADFAK LAGESSLDKA 190 200 210 220 230 240 SATNGGVIGY ILLNQPGQLV PEFENKAFAL KVNEVSTPVK TDYGWHIIKV LEKKPVPIPT 250 260 270 280 KEEAKMTIDN VLAAEILKKY ISDLEAKADL KIMLPPAANN EAKK

References

[1]

"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens." Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D. PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RML369-C.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000087 Genomic DNA. Translation: ABE04979.1.
RefSeq	YP_538068.1. NC_007940.1.
3D structure databases
ProteinModelPortal	Q1RI35.
ModBase	Search...
Protein-protein interaction databases
STRING	336407.RBE_0898.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABE04979; ABE04979; RBE_0898.
GeneID	3995265.
KEGG	rbe:RBE_0898.
PATRIC	17883317. VBIRicBel102610_1022.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0760.
HOGENOM	HOG000014031.
KO	K01802.
OMA	SNITDKM.
ProtClustDB	CLSK870998.
Enzyme and pathway databases
BioCyc	RBEL336407:GJCY-920-MONOMER.
Family and domain databases
InterPro	IPR000297. PPIase_PpiC. IPR023058. PPIase_PpiC_CS. IPR027304. Trigger_fact/SurA_dom. [Graphical view]
SUPFAM	SSF109998. Trigger_fac_C_bac. 1 hit.
PROSITE	PS01096. PPIC_PPIASE_1. 1 hit. PS50198. PPIC_PPIASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PLP_RICBR

Accession

Primary (citable) accession number: Q1RI35

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 29, 2007
Last sequence update:	May 16, 2006
Last modified:	May 1, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program