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Q1RI04

- DNAB_RICBR

UniProt

Q1RI04 - DNAB_RICBR

Protein

Replicative DNA helicase

Gene

dnaB

Organism
Rickettsia bellii (strain RML369-C)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 57 (01 Oct 2014)
      Sequence version 1 (16 May 2006)
      Previous versions | rss
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    Functioni

    Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.By similarity

    Catalytic activityi

    ATP + H2O = ADP + phosphate.

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi228 – 2358ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: UniProtKB-KW
    3. DNA helicase activity Source: InterPro

    GO - Biological processi

    1. DNA replication, synthesis of RNA primer Source: UniProtKB-KW

    Keywords - Molecular functioni

    Helicase, Hydrolase

    Keywords - Biological processi

    DNA replication

    Keywords - Ligandi

    ATP-binding, DNA-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciRBEL336407:GJCY-954-MONOMER.
    RETL1328306-WGS:GSTH-1448-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Replicative DNA helicase (EC:3.6.4.12)
    Gene namesi
    Name:dnaB
    Ordered Locus Names:RBE_0929
    OrganismiRickettsia bellii (strain RML369-C)
    Taxonomic identifieri336407 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group
    ProteomesiUP000001951: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. primosome complex Source: UniProtKB-KW

    Keywords - Cellular componenti

    Primosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 498498Replicative DNA helicasePRO_0000281066Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi336407.RBE_0929.

    Structurei

    3D structure databases

    ProteinModelPortaliQ1RI04.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini197 – 493297SF4 helicasePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the helicase family. DnaB subfamily.Curated
    Contains 1 SF4 helicase domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0305.
    HOGENOMiHOG000113195.
    KOiK02314.
    OMAiVFFDPLH.
    OrthoDBiEOG6T4RW5.

    Family and domain databases

    Gene3Di1.10.860.10. 1 hit.
    3.40.50.300. 1 hit.
    InterProiIPR007692. DNA_helicase_DnaB.
    IPR007694. DNA_helicase_DnaB-like_C.
    IPR007693. DNA_helicase_DnaB-like_N.
    IPR016136. DNA_helicase_N/primase_C.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF00772. DnaB. 1 hit.
    PF03796. DnaB_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF48024. SSF48024. 1 hit.
    SSF52540. SSF52540. 2 hits.
    TIGRFAMsiTIGR00665. DnaB. 1 hit.
    PROSITEiPS51199. SF4_HELICASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q1RI04-1 [UniParc]FASTAAdd to Basket

    « Hide

    MARNKTNNDK NIANDEASTV LARVLPSNVQ AEQMLLGAIL TNNELLNYVS    50
    EFLRSEHFFE PIHQKIYNGI EVITEKGLIA TPITLRSMLA NDELFHEMEG 100
    AEYLAKLVTM SMMVINPIDY GKIIYDLAIK RYLINIGEEV VNDAYNSSLE 150
    FEAKEQIERA ESKLYDLASE GINEKSFTKI AIPISESIAS INRAMKNNDH 200
    VIGISTGLID LDSKLFGFHN SDLVILAGRP AMGKTAFALN LALNACNNML 250
    IKNKRDNEEV QSVGFFSLEM SSEQLTTRLL SMSAGIDSTT LRTGMINEAN 300
    YNRLRKEAIA LSELSFFIDD TPALTISAIR TRARRMKRKH NLGILFVDYL 350
    QLIRGVSKSD NRVNEVSEIT QGLKAIAKEL NIPVIALSQL SRAVELREDK 400
    RPMLSDLRES GSIEQDADIV MFIYREEYYL SRKEPAASDP KHAEKYAEWQ 450
    DNMSKAHNIT DIIIAKHRSG PVGNVQLFYD SQYSKFVNLE TKYPVHPR 498
    Length:498
    Mass (Da):56,183
    Last modified:May 16, 2006 - v1
    Checksum:i6E0500E572F93C08
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000087 Genomic DNA. Translation: ABE05010.1.
    RefSeqiYP_538099.1. NC_007940.1.

    Genome annotation databases

    EnsemblBacteriaiABE05010; ABE05010; RBE_0929.
    GeneIDi3994940.
    KEGGirbe:RBE_0929.
    PATRICi17883391. VBIRicBel102610_1056.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000087 Genomic DNA. Translation: ABE05010.1 .
    RefSeqi YP_538099.1. NC_007940.1.

    3D structure databases

    ProteinModelPortali Q1RI04.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 336407.RBE_0929.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABE05010 ; ABE05010 ; RBE_0929 .
    GeneIDi 3994940.
    KEGGi rbe:RBE_0929.
    PATRICi 17883391. VBIRicBel102610_1056.

    Phylogenomic databases

    eggNOGi COG0305.
    HOGENOMi HOG000113195.
    KOi K02314.
    OMAi VFFDPLH.
    OrthoDBi EOG6T4RW5.

    Enzyme and pathway databases

    BioCyci RBEL336407:GJCY-954-MONOMER.
    RETL1328306-WGS:GSTH-1448-MONOMER.

    Family and domain databases

    Gene3Di 1.10.860.10. 1 hit.
    3.40.50.300. 1 hit.
    InterProi IPR007692. DNA_helicase_DnaB.
    IPR007694. DNA_helicase_DnaB-like_C.
    IPR007693. DNA_helicase_DnaB-like_N.
    IPR016136. DNA_helicase_N/primase_C.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF00772. DnaB. 1 hit.
    PF03796. DnaB_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48024. SSF48024. 1 hit.
    SSF52540. SSF52540. 2 hits.
    TIGRFAMsi TIGR00665. DnaB. 1 hit.
    PROSITEi PS51199. SF4_HELICASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
      Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
      PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: RML369-C.

    Entry informationi

    Entry nameiDNAB_RICBR
    AccessioniPrimary (citable) accession number: Q1RI04
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 20, 2007
    Last sequence update: May 16, 2006
    Last modified: October 1, 2014
    This is version 57 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia bellii strain RML369-C
      Rickettsia bellii (strain RML369-C): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3