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Q1RI04 (DNAB_RICBR) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Replicative DNA helicase

EC=3.6.4.12
Gene names
Name:dnaB
Ordered Locus Names:RBE_0929
OrganismRickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]
Taxonomic identifier336407 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group

Protein attributes

Sequence length498 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins By similarity.

Catalytic activity

ATP + H2O = ADP + phosphate.

Sequence similarities

Belongs to the helicase family. DnaB subfamily.

Contains 1 SF4 helicase domain.

Ontologies

Keywords
   Biological processDNA replication
   Cellular componentPrimosome
   LigandATP-binding
DNA-binding
Nucleotide-binding
   Molecular functionHelicase
Hydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processDNA replication, synthesis of RNA primer

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentprimosome complex

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

DNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

DNA helicase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 498498Replicative DNA helicase
PRO_0000281066

Regions

Domain197 – 493297SF4 helicase
Nucleotide binding228 – 2358ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q1RI04 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: 6E0500E572F93C08

FASTA49856,183
        10         20         30         40         50         60 
MARNKTNNDK NIANDEASTV LARVLPSNVQ AEQMLLGAIL TNNELLNYVS EFLRSEHFFE 

        70         80         90        100        110        120 
PIHQKIYNGI EVITEKGLIA TPITLRSMLA NDELFHEMEG AEYLAKLVTM SMMVINPIDY 

       130        140        150        160        170        180 
GKIIYDLAIK RYLINIGEEV VNDAYNSSLE FEAKEQIERA ESKLYDLASE GINEKSFTKI 

       190        200        210        220        230        240 
AIPISESIAS INRAMKNNDH VIGISTGLID LDSKLFGFHN SDLVILAGRP AMGKTAFALN 

       250        260        270        280        290        300 
LALNACNNML IKNKRDNEEV QSVGFFSLEM SSEQLTTRLL SMSAGIDSTT LRTGMINEAN 

       310        320        330        340        350        360 
YNRLRKEAIA LSELSFFIDD TPALTISAIR TRARRMKRKH NLGILFVDYL QLIRGVSKSD 

       370        380        390        400        410        420 
NRVNEVSEIT QGLKAIAKEL NIPVIALSQL SRAVELREDK RPMLSDLRES GSIEQDADIV 

       430        440        450        460        470        480 
MFIYREEYYL SRKEPAASDP KHAEKYAEWQ DNMSKAHNIT DIIIAKHRSG PVGNVQLFYD 

       490 
SQYSKFVNLE TKYPVHPR 

« Hide

References

[1]"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RML369-C.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000087 Genomic DNA. Translation: ABE05010.1.
RefSeqYP_538099.1. NC_007940.1.

3D structure databases

ProteinModelPortalQ1RI04.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING336407.RBE_0929.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE05010; ABE05010; RBE_0929.
GeneID3994940.
KEGGrbe:RBE_0929.
PATRIC17883391. VBIRicBel102610_1056.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0305.
HOGENOMHOG000113195.
KOK02314.
OMAVFFDPLH.
OrthoDBEOG6T4RW5.

Enzyme and pathway databases

BioCycRBEL336407:GJCY-954-MONOMER.
RETL1328306-WGS:GSTH-1448-MONOMER.

Family and domain databases

Gene3D1.10.860.10. 1 hit.
3.40.50.300. 1 hit.
InterProIPR007692. DNA_helicase_DnaB.
IPR007694. DNA_helicase_DnaB-like_C.
IPR007693. DNA_helicase_DnaB-like_N.
IPR016136. DNA_helicase_N/primase_C.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF00772. DnaB. 1 hit.
PF03796. DnaB_C. 1 hit.
[Graphical view]
SUPFAMSSF48024. SSF48024. 1 hit.
SSF52540. SSF52540. 2 hits.
TIGRFAMsTIGR00665. DnaB. 1 hit.
PROSITEPS51199. SF4_HELICASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDNAB_RICBR
AccessionPrimary (citable) accession number: Q1RI04
Entry history
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: May 16, 2006
Last modified: July 9, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia bellii strain RML369-C

Rickettsia bellii (strain RML369-C): entries and gene names