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Q1RHZ6 (RUVA_RICBR) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Holliday junction ATP-dependent DNA helicase RuvA

EC=3.6.4.12
Gene names
Name:ruvA
Ordered Locus Names:RBE_0937
OrganismRickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]
Taxonomic identifier336407 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group

Protein attributes

Sequence length203 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB By similarity. HAMAP-Rule MF_00031

Catalytic activity

ATP + H2O = ADP + phosphate. HAMAP-Rule MF_00031

Subunit structure

Forms a complex with RuvB By similarity. HAMAP-Rule MF_00031

Sequence similarities

Belongs to the RuvA family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 203203Holliday junction ATP-dependent DNA helicase RuvA HAMAP-Rule MF_00031
PRO_0000278071

Sequences

Sequence LengthMass (Da)Tools
Q1RHZ6 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: 4ECADDE77A67A7B8

FASTA20322,279
        10         20         30         40         50         60 
MIGKLSGRVD SSYDDYVIID VSGVGYRVFA SAKTLSKLSE GESYKLFIET HVREDHINLY 

        70         80         90        100        110        120 
GFLSLEEKSF FNLLQSVNGI GTRMALSILS TLTPTDIQIA INNEDKNIFK AISGVGAKLA 

       130        140        150        160        170        180 
ERIVRELSDK VAKISSSSAA IKDSLNIKGI TPVASSEVIK ALINMGFSRF EAQNAVQEII 

       190        200 
TKNPEISIDE LIRTALKNRN SNF 

« Hide

References

[1]"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RML369-C.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000087 Genomic DNA. Translation: ABE05018.1.
RefSeqYP_538107.1. NC_007940.1.

3D structure databases

ProteinModelPortalQ1RHZ6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING336407.RBE_0937.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE05018; ABE05018; RBE_0937.
GeneID3994948.
KEGGrbe:RBE_0937.
PATRIC17883409. VBIRicBel102610_1065.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0632.
HOGENOMHOG000057115.
KOK03550.
OMAVGYQVHC.
OrthoDBEOG679THG.
ProtClustDBPRK00116.

Enzyme and pathway databases

BioCycRBEL336407:GJCY-962-MONOMER.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
HAMAPMF_00031. DNA_helic_RuvA.
InterProIPR011114. DNA_helicas_Holl-junc_RuvA_C.
IPR013849. DNA_helicase_Holl-junc_RuvA_I.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR012340. NA-bd_OB-fold.
IPR000085. RuvA.
IPR010994. RuvA_2-like.
[Graphical view]
PfamPF07499. RuvA_C. 1 hit.
PF01330. RuvA_N. 1 hit.
[Graphical view]
SMARTSM00278. HhH1. 2 hits.
[Graphical view]
SUPFAMSSF46929. SSF46929. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00084. ruvA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRUVA_RICBR
AccessionPrimary (citable) accession number: Q1RHZ6
Entry history
Integrated into UniProtKB/Swiss-Prot: February 20, 2007
Last sequence update: May 16, 2006
Last modified: April 16, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia bellii strain RML369-C

Rickettsia bellii (strain RML369-C): entries and gene names