Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Tyrosine recombinase XerD

Gene

xerD

Organism
Rickettsia bellii (strain RML369-C)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei145UniRule annotation1
Active sitei175UniRule annotation1
Active sitei250UniRule annotation1
Active sitei253UniRule annotation1
Active sitei276UniRule annotation1
Active sitei285O-(3'-phospho-DNA)-tyrosine intermediateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division, Chromosome partition, DNA integration, DNA recombination

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Tyrosine recombinase XerDUniRule annotation
Gene namesi
Name:xerDUniRule annotation
Ordered Locus Names:RBE_1002
OrganismiRickettsia bellii (strain RML369-C)
Taxonomic identifieri336407 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group
Proteomesi
  • UP000001951 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002723681 – 305Tyrosine recombinase XerDAdd BLAST305

Interactioni

Subunit structurei

Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ1RHT1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the 'phage' integrase family. XerD subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000045296.
KOiK04763.
OMAiYLAFRVE.
OrthoDBiPOG091H00PN.

Family and domain databases

Gene3Di1.10.150.130. 1 hit.
1.10.443.10. 1 hit.
HAMAPiMF_01808. Recomb_XerC_XerD. 1 hit.
MF_01807. Recomb_XerD. 1 hit.
InterProiIPR011010. DNA_brk_join_enz.
IPR013762. Integrase-like_cat.
IPR002104. Integrase_catalytic.
IPR023109. Integrase_recombinase_N.
IPR004107. Integrase_SAM-like_N.
IPR011932. Recomb_XerD.
IPR023009. Tyrosine_recombinase_XerC/XerD.
[Graphical view]
PfamiPF02899. Phage_int_SAM_1. 1 hit.
PF00589. Phage_integrase. 1 hit.
[Graphical view]
SUPFAMiSSF56349. SSF56349. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1RHT1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEFISQFLEM LLAERALSKN SILSYKRDLL DFHNYLAKQK LSELNITTDN
60 70 80 90 100
IRNWVEYLAE NSLQARSINR KISTIKSYYE FLISENHTNL NPLLNIDLPK
110 120 130 140 150
YQNKLPEILS IDDIKSLLEY CSQDISPEGA RLNAMIHLLY ASGLRVSELV
160 170 180 190 200
SLKLSDILSN KVSREVKKIF SVLGKGNKER IIVINEPAIN SLVKYLVVRD
210 220 230 240 250
NFVNKTKPKN LIYLFPSSAA AGYMTRQNFA ILLKSAALYA GLNPEHISPH
260 270 280 290 300
VLRHSFASHL LEGGADLRVI QELLGHADIS TTQIYTHLQT NHLKKALLHH

PLSKN
Length:305
Mass (Da):34,689
Last modified:May 16, 2006 - v1
Checksum:iB98383395AFBC544
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000087 Genomic DNA. Translation: ABE05083.1.
RefSeqiWP_011477663.1. NC_007940.1.

Genome annotation databases

EnsemblBacteriaiABE05083; ABE05083; RBE_1002.
KEGGirbe:RBE_1002.
PATRICi17883555. VBIRicBel102610_1135.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000087 Genomic DNA. Translation: ABE05083.1.
RefSeqiWP_011477663.1. NC_007940.1.

3D structure databases

ProteinModelPortaliQ1RHT1.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABE05083; ABE05083; RBE_1002.
KEGGirbe:RBE_1002.
PATRICi17883555. VBIRicBel102610_1135.

Phylogenomic databases

HOGENOMiHOG000045296.
KOiK04763.
OMAiYLAFRVE.
OrthoDBiPOG091H00PN.

Family and domain databases

Gene3Di1.10.150.130. 1 hit.
1.10.443.10. 1 hit.
HAMAPiMF_01808. Recomb_XerC_XerD. 1 hit.
MF_01807. Recomb_XerD. 1 hit.
InterProiIPR011010. DNA_brk_join_enz.
IPR013762. Integrase-like_cat.
IPR002104. Integrase_catalytic.
IPR023109. Integrase_recombinase_N.
IPR004107. Integrase_SAM-like_N.
IPR011932. Recomb_XerD.
IPR023009. Tyrosine_recombinase_XerC/XerD.
[Graphical view]
PfamiPF02899. Phage_int_SAM_1. 1 hit.
PF00589. Phage_integrase. 1 hit.
[Graphical view]
SUPFAMiSSF56349. SSF56349. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiXERD_RICBR
AccessioniPrimary (citable) accession number: Q1RHT1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: May 16, 2006
Last modified: November 2, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia bellii strain RML369-C
    Rickettsia bellii (strain RML369-C): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.