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Protein

Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C

Gene

gatC

Organism
Rickettsia bellii (strain RML369-C)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).UniRule annotation

Catalytic activityi

ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate.UniRule annotation
ATP + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + phosphate + L-asparaginyl-tRNA(Asn) + L-glutamate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. regulation of translational fidelity Source: InterPro
  2. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciRBEL336407:GJCY-1167-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit CUniRule annotation (EC:6.3.5.-UniRule annotation)
Short name:
Asp/Glu-ADT subunit CUniRule annotation
Gene namesi
Name:gatCUniRule annotation
Ordered Locus Names:RBE_1133
OrganismiRickettsia bellii (strain RML369-C)
Taxonomic identifieri336407 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group
ProteomesiUP000001951 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 100100Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit CPRO_0000274842Add
BLAST

Interactioni

Subunit structurei

Heterotrimer of A, B and C subunits.UniRule annotation

Protein-protein interaction databases

STRINGi336407.RBE_1133.

Family & Domainsi

Sequence similaritiesi

Belongs to the GatC family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0721.
HOGENOMiHOG000017523.
KOiK02435.
OMAiMITKEEV.
OrthoDBiEOG61S35Z.

Family and domain databases

HAMAPiMF_00122. GatC.
InterProiIPR003837. Asp/Glu-ADT_csu.
[Graphical view]
PfamiPF02686. Glu-tRNAGln. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00135. gatC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1RHF0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MITKEEVKKI AKLARLKFEE DKVEEFSSRL SSIMDMIDIL NEIDCTDVKP
60 70 80 90 100
LTSVCDMQAR MRPDEVTSKD HSNELFDNVQ GASQQLAKEV KYFITPKVVE
Length:100
Mass (Da):11,497
Last modified:May 16, 2006 - v1
Checksum:i216C1D8332481DBF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000087 Genomic DNA. Translation: ABE05214.1.
RefSeqiYP_538303.1. NC_007940.1.

Genome annotation databases

EnsemblBacteriaiABE05214; ABE05214; RBE_1133.
KEGGirbe:RBE_1133.
PATRICi17883855. VBIRicBel102610_1279.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000087 Genomic DNA. Translation: ABE05214.1.
RefSeqiYP_538303.1. NC_007940.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi336407.RBE_1133.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABE05214; ABE05214; RBE_1133.
KEGGirbe:RBE_1133.
PATRICi17883855. VBIRicBel102610_1279.

Phylogenomic databases

eggNOGiCOG0721.
HOGENOMiHOG000017523.
KOiK02435.
OMAiMITKEEV.
OrthoDBiEOG61S35Z.

Enzyme and pathway databases

BioCyciRBEL336407:GJCY-1167-MONOMER.

Family and domain databases

HAMAPiMF_00122. GatC.
InterProiIPR003837. Asp/Glu-ADT_csu.
[Graphical view]
PfamiPF02686. Glu-tRNAGln. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00135. gatC. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
    Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
    PLoS Genet. 2:733-744(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RML369-C.

Entry informationi

Entry nameiGATC_RICBR
AccessioniPrimary (citable) accession number: Q1RHF0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: May 16, 2006
Last modified: April 1, 2015
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia bellii strain RML369-C
    Rickettsia bellii (strain RML369-C): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.