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Protein

DNA-directed RNA polymerase subunit beta

Gene

rpoB

Organism
Rickettsia bellii (strain RML369-C)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Enzyme and pathway databases

BioCyciRBEL336407:GJCY-1187-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit betaUniRule annotation (EC:2.7.7.6UniRule annotation)
Short name:
RNAP subunit betaUniRule annotation
Alternative name(s):
RNA polymerase subunit betaUniRule annotation
Transcriptase subunit betaUniRule annotation
Gene namesi
Name:rpoBUniRule annotation
Ordered Locus Names:RBE_1153
OrganismiRickettsia bellii (strain RML369-C)
Taxonomic identifieri336407 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group
ProteomesiUP000001951 Componenti: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 13721372DNA-directed RNA polymerase subunit betaPRO_0000272393Add
BLAST

Interactioni

Subunit structurei

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ1RHD0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA polymerase beta chain family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0085.
HOGENOMiHOG000218612.
KOiK03043.
OMAiYFNPKRY.
OrthoDBiEOG6M9DS6.

Family and domain databases

Gene3Di2.30.150.10. 1 hit.
2.40.270.10. 2 hits.
2.40.50.150. 2 hits.
3.90.1110.10. 2 hits.
HAMAPiMF_01321. RNApol_bact_RpoB.
InterProiIPR010243. DNA-dir_RNA_pol_bsu.
IPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view]
PANTHERiPTHR20856. PTHR20856. 1 hit.
PfamiPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 2 hits.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02013. rpoB. 1 hit.
PROSITEiPS01166. RNA_POL_BETA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1RHD0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSLRDNIEV QPLSHNKRVR KNFGHINLVA DIPNLIEIQK NSYEKNFLQL
60 70 80 90 100
DTKDSERKNK GLQSILNSIF PISDPSNIAN LEFVKYEFDT PKYDVEECTQ
110 120 130 140 150
RSLSYDSALK VTLRLSIWDI DEDTGSREIK GIKEQQVYMG NIPLMTKNGT
160 170 180 190 200
FIINGTERVV VSQMHRSPGV FFYHDEGKVH SSRKLLYSAR VIPYRGSWLD
210 220 230 240 250
LEFDAKDIIY FRIDRKRKLY ATTLLKAIGM STEEIIKFYY DSVNYKVVKN
260 270 280 290 300
KGWAVKFMPS HITAHRLTSD LIDADTGNVL LKAGQKITPR LAKKYAGEGL
310 320 330 340 350
NNILVSHKAL IGKYLSEDLK DPESDEILAK IGEMITVELL SVISDLKIKN
360 370 380 390 400
ISVLVINPQS GPYIRNTLFS DKNQDRESAL FDIFRVLRPG EPANIEAAES
410 420 430 440 450
LFYNLFFDPE RYDLSEVGRI KMNSRLELNI SDETTVLTTD DIKNILRVLV
460 470 480 490 500
ELKDRKGIID DIDHLGNRRV RSVGELIENQ FRIGLVRMEK SVVERMSAGD
510 520 530 540 550
IDTVMPHDLV NSKILVSVVK EFFSTSQLSQ FMDQTNPLSE ITHKRRLSAL
560 570 580 590 600
GPGGLSRDRA GFEVRDVHPT HYGRICPIET PEGQNIGLIN SMATYARINK
610 620 630 640 650
HGFIESPYRK VKDGHVTDEV VYLSAIEEGK YKIGQANSKV DKDGILQGEF
660 670 680 690 700
INCRVEGGNF VMVEPHEVDF IDVTPMQVVS VAASLIPFLE NDDANRALMG
710 720 730 740 750
SNMQRQAVPL IKTDAPFVGT GVEGVVAKDS GASVLALNDG IVEQVDSNRI
760 770 780 790 800
VIRAIAQKTE SAPSVDIYNL LKFQKSNHNT CINQKPLVKV GHYVKKNDII
810 820 830 840 850
ADGPSTDNGE IALGRNVLVA FLPWNGYNFE DSILISERIV KEDVFTSVHI
860 870 880 890 900
EEFEVIARDT RLGPEEITRD IPNVSEEALR HLDEVGIIYV GAEVKAGDIL
910 920 930 940 950
VGKVTPKSES PITPEEKLLR AIFGEKAFDV KDSSLHVPSG VSGTVVEVRV
960 970 980 990 1000
FSRRGVEKDQ RAIAIEKQQI EKLAKDRDDE LEIIEHFVFS WLEKLLVGQV
1010 1020 1030 1040 1050
SINGPKTVKT GQTITSEILK GLSKGQLWQF TVEDANVMNE IEQLKGHYDG
1060 1070 1080 1090 1100
KKEALNKRFA TKVEKLQSGD DLPQGALKVV KVFIATKHKL QPGDKMAGRH
1110 1120 1130 1140 1150
GNKGVISRIV PEEDMPFLED GTVVDIVLNP LGLPSRMNIG QVLETHLGWA
1160 1170 1180 1190 1200
SVNLAKKIAG LVEEHKTKHA SIEKIKKFLI ELYGENINHI LEKSDEEIIS
1210 1220 1230 1240 1250
FCNEAAKGVY FATPVFDGAK VEDVKDMLRL AGQDLSGQVK LIDGRTGEYF
1260 1270 1280 1290 1300
DRLVTVGQKY LLKLHHLVDN KIHSRSIGPY SLVTQQPLGG KSHFGGQRFG
1310 1320 1330 1340 1350
EMECWALQAY GAAYTLQEML TVKSDDVNGR IKIYDSIVRG ENNFESGIPE
1360 1370
SFNVMIKEFR SLCLNVKLEV TS
Length:1,372
Mass (Da):153,845
Last modified:May 16, 2006 - v1
Checksum:i72431578B8F20B58
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000087 Genomic DNA. Translation: ABE05234.1.
RefSeqiWP_011477812.1. NC_007940.1.

Genome annotation databases

EnsemblBacteriaiABE05234; ABE05234; RBE_1153.
KEGGirbe:RBE_1153.
PATRICi17883903. VBIRicBel102610_1303.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000087 Genomic DNA. Translation: ABE05234.1.
RefSeqiWP_011477812.1. NC_007940.1.

3D structure databases

ProteinModelPortaliQ1RHD0.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABE05234; ABE05234; RBE_1153.
KEGGirbe:RBE_1153.
PATRICi17883903. VBIRicBel102610_1303.

Phylogenomic databases

eggNOGiCOG0085.
HOGENOMiHOG000218612.
KOiK03043.
OMAiYFNPKRY.
OrthoDBiEOG6M9DS6.

Enzyme and pathway databases

BioCyciRBEL336407:GJCY-1187-MONOMER.

Family and domain databases

Gene3Di2.30.150.10. 1 hit.
2.40.270.10. 2 hits.
2.40.50.150. 2 hits.
3.90.1110.10. 2 hits.
HAMAPiMF_01321. RNApol_bact_RpoB.
InterProiIPR010243. DNA-dir_RNA_pol_bsu.
IPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view]
PANTHERiPTHR20856. PTHR20856. 1 hit.
PfamiPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 2 hits.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02013. rpoB. 1 hit.
PROSITEiPS01166. RNA_POL_BETA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
    Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
    PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RML369-C.

Entry informationi

Entry nameiRPOB_RICBR
AccessioniPrimary (citable) accession number: Q1RHD0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: May 16, 2006
Last modified: July 22, 2015
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia bellii strain RML369-C
    Rickettsia bellii (strain RML369-C): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.