Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q1RHD0

- RPOB_RICBR

UniProt

Q1RHD0 - RPOB_RICBR

Protein

DNA-directed RNA polymerase subunit beta

Gene

rpoB

Organism
Rickettsia bellii (strain RML369-C)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 60 (01 Oct 2014)
      Sequence version 1 (16 May 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.UniRule annotation

    Catalytic activityi

    Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-HAMAP
    2. DNA-directed RNA polymerase activity Source: UniProtKB-HAMAP
    3. ribonucleoside binding Source: InterPro

    GO - Biological processi

    1. transcription, DNA-templated Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Nucleotidyltransferase, Transferase

    Keywords - Biological processi

    Transcription

    Enzyme and pathway databases

    BioCyciRBEL336407:GJCY-1187-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA-directed RNA polymerase subunit betaUniRule annotation (EC:2.7.7.6UniRule annotation)
    Short name:
    RNAP subunit betaUniRule annotation
    Alternative name(s):
    RNA polymerase subunit betaUniRule annotation
    Transcriptase subunit betaUniRule annotation
    Gene namesi
    Name:rpoBUniRule annotation
    Ordered Locus Names:RBE_1153
    OrganismiRickettsia bellii (strain RML369-C)
    Taxonomic identifieri336407 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group
    ProteomesiUP000001951: Chromosome

    Subcellular locationi

    Keywords - Cellular componenti

    DNA-directed RNA polymerase

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 13721372DNA-directed RNA polymerase subunit betaPRO_0000272393Add
    BLAST

    Interactioni

    Subunit structurei

    The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.UniRule annotation

    Protein-protein interaction databases

    STRINGi336407.RBE_1153.

    Structurei

    3D structure databases

    ProteinModelPortaliQ1RHD0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the RNA polymerase beta chain family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0085.
    HOGENOMiHOG000218612.
    KOiK03043.
    OMAiICPANME.
    OrthoDBiEOG6M9DS6.

    Family and domain databases

    Gene3Di2.30.150.10. 1 hit.
    2.40.270.10. 2 hits.
    2.40.50.150. 2 hits.
    3.90.1110.10. 2 hits.
    HAMAPiMF_01321. RNApol_bact_RpoB.
    InterProiIPR010243. DNA-dir_RNA_pol_bsu.
    IPR019462. DNA-dir_RNA_pol_bsu_external_1.
    IPR015712. DNA-dir_RNA_pol_su2.
    IPR007120. DNA-dir_RNA_pol_su2_6.
    IPR007121. RNA_pol_bsu_CS.
    IPR007644. RNA_pol_bsu_protrusion.
    IPR007642. RNA_pol_Rpb2_2.
    IPR007645. RNA_pol_Rpb2_3.
    IPR007641. RNA_pol_Rpb2_7.
    IPR014724. RNA_pol_RPB2_OB-fold.
    [Graphical view]
    PANTHERiPTHR20856. PTHR20856. 1 hit.
    PfamiPF04563. RNA_pol_Rpb2_1. 1 hit.
    PF04561. RNA_pol_Rpb2_2. 2 hits.
    PF04565. RNA_pol_Rpb2_3. 1 hit.
    PF10385. RNA_pol_Rpb2_45. 1 hit.
    PF00562. RNA_pol_Rpb2_6. 1 hit.
    PF04560. RNA_pol_Rpb2_7. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR02013. rpoB. 1 hit.
    PROSITEiPS01166. RNA_POL_BETA. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q1RHD0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVSLRDNIEV QPLSHNKRVR KNFGHINLVA DIPNLIEIQK NSYEKNFLQL     50
    DTKDSERKNK GLQSILNSIF PISDPSNIAN LEFVKYEFDT PKYDVEECTQ 100
    RSLSYDSALK VTLRLSIWDI DEDTGSREIK GIKEQQVYMG NIPLMTKNGT 150
    FIINGTERVV VSQMHRSPGV FFYHDEGKVH SSRKLLYSAR VIPYRGSWLD 200
    LEFDAKDIIY FRIDRKRKLY ATTLLKAIGM STEEIIKFYY DSVNYKVVKN 250
    KGWAVKFMPS HITAHRLTSD LIDADTGNVL LKAGQKITPR LAKKYAGEGL 300
    NNILVSHKAL IGKYLSEDLK DPESDEILAK IGEMITVELL SVISDLKIKN 350
    ISVLVINPQS GPYIRNTLFS DKNQDRESAL FDIFRVLRPG EPANIEAAES 400
    LFYNLFFDPE RYDLSEVGRI KMNSRLELNI SDETTVLTTD DIKNILRVLV 450
    ELKDRKGIID DIDHLGNRRV RSVGELIENQ FRIGLVRMEK SVVERMSAGD 500
    IDTVMPHDLV NSKILVSVVK EFFSTSQLSQ FMDQTNPLSE ITHKRRLSAL 550
    GPGGLSRDRA GFEVRDVHPT HYGRICPIET PEGQNIGLIN SMATYARINK 600
    HGFIESPYRK VKDGHVTDEV VYLSAIEEGK YKIGQANSKV DKDGILQGEF 650
    INCRVEGGNF VMVEPHEVDF IDVTPMQVVS VAASLIPFLE NDDANRALMG 700
    SNMQRQAVPL IKTDAPFVGT GVEGVVAKDS GASVLALNDG IVEQVDSNRI 750
    VIRAIAQKTE SAPSVDIYNL LKFQKSNHNT CINQKPLVKV GHYVKKNDII 800
    ADGPSTDNGE IALGRNVLVA FLPWNGYNFE DSILISERIV KEDVFTSVHI 850
    EEFEVIARDT RLGPEEITRD IPNVSEEALR HLDEVGIIYV GAEVKAGDIL 900
    VGKVTPKSES PITPEEKLLR AIFGEKAFDV KDSSLHVPSG VSGTVVEVRV 950
    FSRRGVEKDQ RAIAIEKQQI EKLAKDRDDE LEIIEHFVFS WLEKLLVGQV 1000
    SINGPKTVKT GQTITSEILK GLSKGQLWQF TVEDANVMNE IEQLKGHYDG 1050
    KKEALNKRFA TKVEKLQSGD DLPQGALKVV KVFIATKHKL QPGDKMAGRH 1100
    GNKGVISRIV PEEDMPFLED GTVVDIVLNP LGLPSRMNIG QVLETHLGWA 1150
    SVNLAKKIAG LVEEHKTKHA SIEKIKKFLI ELYGENINHI LEKSDEEIIS 1200
    FCNEAAKGVY FATPVFDGAK VEDVKDMLRL AGQDLSGQVK LIDGRTGEYF 1250
    DRLVTVGQKY LLKLHHLVDN KIHSRSIGPY SLVTQQPLGG KSHFGGQRFG 1300
    EMECWALQAY GAAYTLQEML TVKSDDVNGR IKIYDSIVRG ENNFESGIPE 1350
    SFNVMIKEFR SLCLNVKLEV TS 1372
    Length:1,372
    Mass (Da):153,845
    Last modified:May 16, 2006 - v1
    Checksum:i72431578B8F20B58
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000087 Genomic DNA. Translation: ABE05234.1.
    RefSeqiWP_011477812.1. NC_007940.1.
    YP_538323.1. NC_007940.1.

    Genome annotation databases

    EnsemblBacteriaiABE05234; ABE05234; RBE_1153.
    GeneIDi3995110.
    KEGGirbe:RBE_1153.
    PATRICi17883903. VBIRicBel102610_1303.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000087 Genomic DNA. Translation: ABE05234.1 .
    RefSeqi WP_011477812.1. NC_007940.1.
    YP_538323.1. NC_007940.1.

    3D structure databases

    ProteinModelPortali Q1RHD0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 336407.RBE_1153.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABE05234 ; ABE05234 ; RBE_1153 .
    GeneIDi 3995110.
    KEGGi rbe:RBE_1153.
    PATRICi 17883903. VBIRicBel102610_1303.

    Phylogenomic databases

    eggNOGi COG0085.
    HOGENOMi HOG000218612.
    KOi K03043.
    OMAi ICPANME.
    OrthoDBi EOG6M9DS6.

    Enzyme and pathway databases

    BioCyci RBEL336407:GJCY-1187-MONOMER.

    Family and domain databases

    Gene3Di 2.30.150.10. 1 hit.
    2.40.270.10. 2 hits.
    2.40.50.150. 2 hits.
    3.90.1110.10. 2 hits.
    HAMAPi MF_01321. RNApol_bact_RpoB.
    InterProi IPR010243. DNA-dir_RNA_pol_bsu.
    IPR019462. DNA-dir_RNA_pol_bsu_external_1.
    IPR015712. DNA-dir_RNA_pol_su2.
    IPR007120. DNA-dir_RNA_pol_su2_6.
    IPR007121. RNA_pol_bsu_CS.
    IPR007644. RNA_pol_bsu_protrusion.
    IPR007642. RNA_pol_Rpb2_2.
    IPR007645. RNA_pol_Rpb2_3.
    IPR007641. RNA_pol_Rpb2_7.
    IPR014724. RNA_pol_RPB2_OB-fold.
    [Graphical view ]
    PANTHERi PTHR20856. PTHR20856. 1 hit.
    Pfami PF04563. RNA_pol_Rpb2_1. 1 hit.
    PF04561. RNA_pol_Rpb2_2. 2 hits.
    PF04565. RNA_pol_Rpb2_3. 1 hit.
    PF10385. RNA_pol_Rpb2_45. 1 hit.
    PF00562. RNA_pol_Rpb2_6. 1 hit.
    PF04560. RNA_pol_Rpb2_7. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR02013. rpoB. 1 hit.
    PROSITEi PS01166. RNA_POL_BETA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
      Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
      PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: RML369-C.

    Entry informationi

    Entry nameiRPOB_RICBR
    AccessioniPrimary (citable) accession number: Q1RHD0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 23, 2007
    Last sequence update: May 16, 2006
    Last modified: October 1, 2014
    This is version 60 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia bellii strain RML369-C
      Rickettsia bellii (strain RML369-C): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3