Q1RHB5 (DHSC_RICBR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Succinate dehydrogenase cytochrome b556 subunit
Short name=Cytochrome b-556

Gene names

Name:	sdhC
Ordered Locus Names:	RBE_1168

Organism

Rickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]

Taxonomic identifier

336407 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › belli group › Rickettsia bellii

Protein attributes

Sequence length	125 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Membrane-anchoring subunit of succinate dehydrogenase (SDH) By similarity.
Cofactor	Heme group. The heme is bound between the two transmembrane subunits By similarity.
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle.
Subunit structure	Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers By similarity.
Subcellular location	Cell inner membrane; Multi-pass membrane protein.
Sequence similarities	Belongs to the cytochrome b560 family.

Ontologies

Keywords
Biological process	Electron transport Transport Tricarboxylic acid cycle
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Ligand	Heme Iron Metal-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-UniPathway
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell succinate dehydrogenase complex Inferred from electronic annotation. Source: InterPro
Molecular_function	electron carrier activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW succinate dehydrogenase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 125	125	Succinate dehydrogenase cytochrome b556 subunit		PRO_0000281050
Regions
	Topological domain	1 – 29	29	Cytoplasmic By similarity
	Transmembrane	30 – 55	26	Helical; By similarity
	Topological domain	56 – 68	13	Periplasmic By similarity
	Transmembrane	69 – 89	21	Helical; By similarity
	Topological domain	90 – 104	15	Cytoplasmic By similarity
	Transmembrane	105 – 125	21	Helical; By similarity
Sites
	Metal binding	84	1	Iron (heme axial ligand); shared with second transmembrane subunit By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q1RHB5 [UniParc]. Last modified May 16, 2006. Version 1. Checksum: A9FD375B6905EF3E	FASTA	125	14,408
	10 20 30 40 50 60 MTKTKQEIYN KRPTSPHLTI YKPQISSTLS ILHRMTGVAL FFAVSILAWW FILSKFDSNY 70 80 90 100 110 120 IKLANCCCII KICLILTSFA WFYHLCNGIR HLFWDIGLGF SIKAVNLTGW SVVICSVLFT ILLWV

References

[1]

"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens." Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D. PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RML369-C.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000087 Genomic DNA. Translation: ABE05249.1.
RefSeq	YP_538338.1. NC_007940.1.
3D structure databases
ProteinModelPortal	Q1RHB5.
ModBase	Search...
Protein-protein interaction databases
STRING	336407.RBE_1168.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABE05249; ABE05249; RBE_1168.
GeneID	3995946.
KEGG	rbe:RBE_1168.
PATRIC	17883935. VBIRicBel102610_1318.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2009.
HOGENOM	HOG000160253.
KO	K00241.
OMA	WALMHHM.
ProtClustDB	CLSK870757.
Enzyme and pathway databases
BioCyc	RBEL336407:GJCY-1203-MONOMER.
UniPathway	UPA00223.
Family and domain databases
InterPro	IPR018495. Succ_DH_cyt_bsu_CS. IPR014314. Succ_DH_cytb556. IPR014361. Succ_DH_cytb560. IPR000701. Succ_DH_Fumarate_Rdtase_TM-su. [Graphical view]
Pfam	PF01127. Sdh_cyt. 1 hit. [Graphical view]
PIRSF	PIRSF000178. SDH_cyt_b560. 1 hit.
TIGRFAMs	TIGR02970. succ_dehyd_cytB. 1 hit.
PROSITE	PS01000. SDH_CYT_1. 1 hit. PS01001. SDH_CYT_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DHSC_RICBR

Accession

Primary (citable) accession number: Q1RHB5

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 20, 2007
Last sequence update:	May 16, 2006
Last modified:	May 1, 2013
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program