Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein translocase subunit SecF

Gene

secF

Organism
Rickettsia bellii (strain RML369-C)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.UniRule annotation

GO - Molecular functioni

  1. P-P-bond-hydrolysis-driven protein transmembrane transporter activity Source: InterPro

GO - Biological processi

  1. intracellular protein transmembrane transport Source: UniProtKB-HAMAP
  2. protein targeting Source: UniProtKB-HAMAP
  3. protein transport by the Sec complex Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

Protein transport, Translocation, Transport

Enzyme and pathway databases

BioCyciRBEL336407:GJCY-1219-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein translocase subunit SecF
Gene namesi
Name:secFUniRule annotation
Ordered Locus Names:RBE_1184
OrganismiRickettsia bellii (strain RML369-C)
Taxonomic identifieri336407 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group
ProteomesiUP000001951: Chromosome

Subcellular locationi

Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei28 – 4821HelicalUniRule annotationAdd
BLAST
Transmembranei140 – 16021HelicalUniRule annotationAdd
BLAST
Transmembranei164 – 18421HelicalUniRule annotationAdd
BLAST
Transmembranei194 – 21421HelicalUniRule annotationAdd
BLAST
Transmembranei246 – 26621HelicalUniRule annotationAdd
BLAST
Transmembranei272 – 29221HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. intracellular Source: GOC
  3. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 303303Protein translocase subunit SecFPRO_0000272637Add
BLAST

Interactioni

Subunit structurei

Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.UniRule annotation

Protein-protein interaction databases

STRINGi336407.RBE_1184.

Structurei

3D structure databases

ProteinModelPortaliQ1RH99.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SecD/SecF family. SecF subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0341.
HOGENOMiHOG000245916.
KOiK03074.
OMAiIDMNLEV.
OrthoDBiEOG676Z5R.

Family and domain databases

HAMAPiMF_01464_B. SecF_B.
InterProiIPR022813. SecD/SecF_arch_bac.
IPR022645. SecD/SecF_bac.
IPR022646. SecD/SecF_CS.
IPR005665. SecF_bac.
IPR000731. SSD.
[Graphical view]
PfamiPF07549. Sec_GG. 1 hit.
PF02355. SecD_SecF. 1 hit.
[Graphical view]
PRINTSiPR01755. SECFTRNLCASE.
TIGRFAMsiTIGR00916. 2A0604s01. 1 hit.
TIGR00966. 3a0501s07. 1 hit.
PROSITEiPS50156. SSD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1RH99-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQIYPLRLLP NKIDFDFMNF KKVSYTFSII LSLISFIWIG MYKFNFGIDF
60 70 80 90 100
AGGIVIEVRL DQTPDLPKMR QVLGELGIGE VVLQNFGSER DLSIRFGSSS
110 120 130 140 150
EDNLMKNIEL IKSTLQNNFP YNFEYRKVDF VGPQVGRQLI EAGTMAMLFS
160 170 180 190 200
FAAIMIYIWV RFEWYFGLGI LIALVHDVIL ALGFMSITKL DFNLSTIAAV
210 220 230 240 250
LTIIGYSVND SVVIYDRIRE NLRKYHKKGI TEIINLSINE TLSRTILTVV
260 270 280 290 300
TTLLANLALV LFGGEAIRSF SVLVFFGIIA GTYSSIFISA PILTIFANKK

FEK
Length:303
Mass (Da):34,349
Last modified:May 16, 2006 - v1
Checksum:i5016D954487DA3E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000087 Genomic DNA. Translation: ABE05265.1.
RefSeqiWP_011477843.1. NC_007940.1.
YP_538354.1. NC_007940.1.

Genome annotation databases

EnsemblBacteriaiABE05265; ABE05265; RBE_1184.
GeneIDi3995270.
KEGGirbe:RBE_1184.
PATRICi17883973. VBIRicBel102610_1337.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000087 Genomic DNA. Translation: ABE05265.1.
RefSeqiWP_011477843.1. NC_007940.1.
YP_538354.1. NC_007940.1.

3D structure databases

ProteinModelPortaliQ1RH99.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi336407.RBE_1184.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABE05265; ABE05265; RBE_1184.
GeneIDi3995270.
KEGGirbe:RBE_1184.
PATRICi17883973. VBIRicBel102610_1337.

Phylogenomic databases

eggNOGiCOG0341.
HOGENOMiHOG000245916.
KOiK03074.
OMAiIDMNLEV.
OrthoDBiEOG676Z5R.

Enzyme and pathway databases

BioCyciRBEL336407:GJCY-1219-MONOMER.

Family and domain databases

HAMAPiMF_01464_B. SecF_B.
InterProiIPR022813. SecD/SecF_arch_bac.
IPR022645. SecD/SecF_bac.
IPR022646. SecD/SecF_CS.
IPR005665. SecF_bac.
IPR000731. SSD.
[Graphical view]
PfamiPF07549. Sec_GG. 1 hit.
PF02355. SecD_SecF. 1 hit.
[Graphical view]
PRINTSiPR01755. SECFTRNLCASE.
TIGRFAMsiTIGR00916. 2A0604s01. 1 hit.
TIGR00966. 3a0501s07. 1 hit.
PROSITEiPS50156. SSD. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
    Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
    PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RML369-C.

Entry informationi

Entry nameiSECF_RICBR
AccessioniPrimary (citable) accession number: Q1RH99
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: May 16, 2006
Last modified: March 4, 2015
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia bellii strain RML369-C
    Rickettsia bellii (strain RML369-C): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.