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Protein

Superoxide dismutase [Mn/Fe]

Gene

sodB

Organism
Rickettsia bellii (strain RML369-C)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.

Cofactori

Mn2+By similarity, Fe2+By similarityNote: Binds 1 Mn(2+) or Fe2+ ion per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi38 – 381Manganese or ironBy similarity
Metal bindingi90 – 901Manganese or ironBy similarity
Metal bindingi172 – 1721Manganese or ironBy similarity
Metal bindingi176 – 1761Manganese or ironBy similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. superoxide dismutase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

Iron, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciRBEL336407:GJCY-1230-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Mn/Fe] (EC:1.15.1.1)
Gene namesi
Name:sodB
Ordered Locus Names:RBE_1195
OrganismiRickettsia bellii (strain RML369-C)
Taxonomic identifieri336407 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group
ProteomesiUP000001951 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 209209Superoxide dismutase [Mn/Fe]PRO_0000286501Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi336407.RBE_1195.

Structurei

3D structure databases

ProteinModelPortaliQ1RH88.
SMRiQ1RH88. Positions 14-208.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0605.
HOGENOMiHOG000013584.
KOiK04564.
OMAiGGGNKLP.
OrthoDBiEOG63NMNT.

Family and domain databases

InterProiIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERiPTHR11404. PTHR11404. 1 hit.
PfamiPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiPS00088. SOD_MN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1RH88-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTYCDKSNQT SYPFVLPNLP YEKESFKPHF TAETFEYHHG KHHNAYVQNL
60 70 80 90 100
NNLLKDKEEL QKKNLEEIID WSSQNQNIAI FNNAAQVWNH TFFWHSIKPN
110 120 130 140 150
GGGKPSGKIL KQINEDFGSF EEFCEQFKAE ATGQFGSGWA WLVYHNNRLQ
160 170 180 190 200
IVKTANAGTP IANGMQPLLA CDVWEHAYYI DYRNKRPDYV DIFIKHMINW

EFVENNLTK
Length:209
Mass (Da):24,496
Last modified:May 15, 2006 - v1
Checksum:i95241EDC5FE971FD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000087 Genomic DNA. Translation: ABE05276.1.
RefSeqiWP_011477854.1. NC_007940.1.
YP_538365.1. NC_007940.1.

Genome annotation databases

EnsemblBacteriaiABE05276; ABE05276; RBE_1195.
KEGGirbe:RBE_1195.
PATRICi17883995. VBIRicBel102610_1348.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000087 Genomic DNA. Translation: ABE05276.1.
RefSeqiWP_011477854.1. NC_007940.1.
YP_538365.1. NC_007940.1.

3D structure databases

ProteinModelPortaliQ1RH88.
SMRiQ1RH88. Positions 14-208.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi336407.RBE_1195.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABE05276; ABE05276; RBE_1195.
KEGGirbe:RBE_1195.
PATRICi17883995. VBIRicBel102610_1348.

Phylogenomic databases

eggNOGiCOG0605.
HOGENOMiHOG000013584.
KOiK04564.
OMAiGGGNKLP.
OrthoDBiEOG63NMNT.

Enzyme and pathway databases

BioCyciRBEL336407:GJCY-1230-MONOMER.

Family and domain databases

InterProiIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERiPTHR11404. PTHR11404. 1 hit.
PfamiPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiPS00088. SOD_MN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
    Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
    PLoS Genet. 2:733-744(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RML369-C.

Entry informationi

Entry nameiSODF_RICBR
AccessioniPrimary (citable) accession number: Q1RH88
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 14, 2007
Last sequence update: May 15, 2006
Last modified: March 31, 2015
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia bellii strain RML369-C
    Rickettsia bellii (strain RML369-C): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.