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Q1RH58 (GPDA_RICBR) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glycerol-3-phosphate dehydrogenase [NAD(P)+]
EC=1.1.1.94
Alternative name(s):
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase
Gene names
Name:gpsA
Ordered Locus Names:RBE_1225
OrganismRickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]
Taxonomic identifier336407 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › belli group ›

Protein attributes

Sequence length314 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

sn-glycerol 3-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H. HAMAP-Rule MF_00394

Pathway

Membrane lipid metabolism; glycerophospholipid metabolism. HAMAP-Rule MF_00394

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 314314Glycerol-3-phosphate dehydrogenase [NAD(P)+] HAMAP-Rule MF_00394
PRO_0000255361

Regions

Nucleotide binding11 – 166NAD By similarity
Region258 – 2592Substrate binding By similarity

Sites

Active site1911Proton acceptor By similarity
Binding site1081NAD; via amide nitrogen By similarity
Binding site1081Substrate By similarity
Binding site1401NAD; via amide nitrogen By similarity
Binding site2581NAD By similarity
Binding site2841NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q1RH58 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: B6DCA89E4070CC51

FASTA31434,243
        10         20         30         40         50         60 
MKRFKNIAVY GGGSFGTSLA AIAARVCENV TLFLRDEEIA KEITDKKTNT KYLGNIKLPS 

        70         80         90        100        110        120 
NLQATTNLDK IKDFELIIIA VPSYAFDEAI KLLKTHISND NILLIATKGF ARNPTELFSD 

       130        140        150        160        170        180 
RLKTLLSNNP IAFLSGPNLA KDLAKGLPAS ATIASLDIDL ANKISYNLSS EAFVASTIND 

       190        200        210        220        230        240 
VITLQVAGAL KNIFAIKSGI DMAKEQGENA KATLIVSALK EIAILSKALG GMKNNMDILL 

       250        260        270        280        290        300 
EAGVVGDLVL TCYSRSSRNT KFGYEFGISK DKQKFLQEYK ELVEGREAIK LVLELIERYD 

       310 
LDMPIVSSLG NVIR

« Hide

References

[1]"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RML369-C.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000087 Genomic DNA. Translation: ABE05306.1.
RefSeqYP_538395.1. NC_007940.1.

3D structure databases

ProteinModelPortalQ1RH58.
ModBaseSearch...

Protein-protein interaction databases

STRING336407.RBE_1225.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE05306; ABE05306; RBE_1225.
GeneID3995493.
KEGGrbe:RBE_1225.
PATRIC17884068. VBIRicBel102610_1383.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0240.
HOGENOMHOG000246854.
KOK00057.
OMAFHVNVIE.
ProtClustDBPRK00094.

Enzyme and pathway databases

BioCycRBEL336407:GJCY-1262-MONOMER.
UniPathwayUPA00940.

Family and domain databases

Gene3D1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
HAMAPMF_00394. NAD_Glyc3P_dehydrog.
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERPTHR11728. PTHR11728. 1 hit.
PfamPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSPR00077. GPDHDRGNASE.
SUPFAMSSF48179. 6DGDH_C_like. 1 hit.
PROSITEPS00957. NAD_G3PDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGPDA_RICBR
AccessionPrimary (citable) accession number: Q1RH58
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: May 16, 2006
Last modified: May 1, 2013
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Rickettsia bellii strain RML369-C

Rickettsia bellii (strain RML369-C): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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