Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glycerol-3-phosphate dehydrogenase [NAD(P)+]

Gene

gpsA

Organism
Rickettsia bellii (strain RML369-C)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H.UniRule annotation

Pathwayi: glycerophospholipid metabolism

This protein is involved in the pathway glycerophospholipid metabolism, which is part of Membrane lipid metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway glycerophospholipid metabolism and in Membrane lipid metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei108NAD; via amide nitrogenUniRule annotation1
Binding sitei108SubstrateUniRule annotation1
Binding sitei140NAD; via amide nitrogenUniRule annotation1
Active sitei191Proton acceptorUniRule annotation1
Binding sitei258NADUniRule annotation1
Binding sitei284NADUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi11 – 16NADUniRule annotation6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processLipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism
LigandNAD

Enzyme and pathway databases

UniPathwayiUPA00940

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(P)+]UniRule annotation (EC:1.1.1.94UniRule annotation)
Alternative name(s):
NAD(P)H-dependent glycerol-3-phosphate dehydrogenaseUniRule annotation
Gene namesi
Name:gpsAUniRule annotation
Ordered Locus Names:RBE_1225
OrganismiRickettsia bellii (strain RML369-C)
Taxonomic identifieri336407 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group
Proteomesi
  • UP000001951 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002553611 – 314Glycerol-3-phosphate dehydrogenase [NAD(P)+]Add BLAST314

Structurei

3D structure databases

ProteinModelPortaliQ1RH58
SMRiQ1RH58
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni258 – 259Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000246854
KOiK00057
OMAiWLCKGFE
OrthoDBiPOG091H060E

Family and domain databases

Gene3Di1.10.1040.10, 1 hit
HAMAPiMF_00394 NAD_Glyc3P_dehydrog, 1 hit
InterProiView protein in InterPro
IPR008927 6-PGluconate_DH-like_C_sf
IPR013328 6PGD_dom2
IPR006168 G3P_DH_NAD-dep
IPR006109 G3P_DH_NAD-dep_C
IPR011128 G3P_DH_NAD-dep_N
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF07479 NAD_Gly3P_dh_C, 1 hit
PF01210 NAD_Gly3P_dh_N, 1 hit
PIRSFiPIRSF000114 Glycerol-3-P_dh, 1 hit
PRINTSiPR00077 GPDHDRGNASE
SUPFAMiSSF48179 SSF48179, 1 hit
SSF51735 SSF51735, 1 hit
PROSITEiView protein in PROSITE
PS00957 NAD_G3PDH, 1 hit

Sequencei

Sequence statusi: Complete.

Q1RH58-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRFKNIAVY GGGSFGTSLA AIAARVCENV TLFLRDEEIA KEITDKKTNT
60 70 80 90 100
KYLGNIKLPS NLQATTNLDK IKDFELIIIA VPSYAFDEAI KLLKTHISND
110 120 130 140 150
NILLIATKGF ARNPTELFSD RLKTLLSNNP IAFLSGPNLA KDLAKGLPAS
160 170 180 190 200
ATIASLDIDL ANKISYNLSS EAFVASTIND VITLQVAGAL KNIFAIKSGI
210 220 230 240 250
DMAKEQGENA KATLIVSALK EIAILSKALG GMKNNMDILL EAGVVGDLVL
260 270 280 290 300
TCYSRSSRNT KFGYEFGISK DKQKFLQEYK ELVEGREAIK LVLELIERYD
310
LDMPIVSSLG NVIR
Length:314
Mass (Da):34,243
Last modified:May 16, 2006 - v1
Checksum:iB6DCA89E4070CC51
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000087 Genomic DNA Translation: ABE05306.1
RefSeqiWP_011477882.1, NC_007940.1

Genome annotation databases

EnsemblBacteriaiABE05306; ABE05306; RBE_1225
KEGGirbe:RBE_1225

Similar proteinsi

Entry informationi

Entry nameiGPDA_RICBR
AccessioniPrimary (citable) accession number: Q1RH58
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: May 16, 2006
Last modified: March 28, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health