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Q1RH55 (SUCC_RICBR) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Succinyl-CoA ligase [ADP-forming] subunit beta

EC=6.2.1.5
Alternative name(s):
Succinyl-CoA synthetase subunit beta
Short name=SCS-beta
Gene names
Name:sucC
Ordered Locus Names:RBE_1228
OrganismRickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]
Taxonomic identifier336407 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group

Protein attributes

Sequence length385 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + succinate + CoA = ADP + phosphate + succinyl-CoA. HAMAP-Rule MF_00558

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity.

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1. HAMAP-Rule MF_00558

Subunit structure

Heterotetramer of two alpha and two beta subunits By similarity.

Sequence similarities

Belongs to the succinate/malate CoA ligase beta subunit family.

Contains 1 ATP-grasp domain.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 385385Succinyl-CoA ligase [ADP-forming] subunit beta HAMAP-Rule MF_00558
PRO_0000277952

Regions

Domain9 – 244236ATP-grasp
Nucleotide binding35 – 10874ATP By similarity

Sites

Metal binding1971Magnesium or manganese By similarity
Metal binding1991Magnesium or manganese By similarity

Sequences

Sequence LengthMass (Da)Tools
Q1RH55 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: 6A29DEB9E686CA57

FASTA38541,594
        10         20         30         40         50         60 
MNIHEYQAKE ILRKYGVPTS TGVVVTKTES INAAIDELNT KVYVVKAQIH AGGRGKAGGV 

        70         80         90        100        110        120 
KVVKSKEEAK KVAHDMFGIN LVTHQTGPQG QKVNRLYIES GCDILKEYYF SVVFDRSASC 

       130        140        150        160        170        180 
ITFIASTEGG VDIEEVAEKT PEKIIKFSVD PATGLQNFHA QGIAYELGFK DHQVKQMKEI 

       190        200        210        220        230        240 
VKATYKAFIE TDAAQIEINP LIVNKEGNLL ALDAKFTFDD NGLFKHPEIM ALRDQDEEDP 

       250        260        270        280        290        300 
LETRAADAGL SYVKMDGSIG CMVNGAGLAM ATMDIIKLYG ATPANFLDVG GGADRERVKE 

       310        320        330        340        350        360 
ALKIILSDKE VKGILVNIFG GIMRCDIIAE GIIAAAKDIG IKVPLVVRLA GTNVEKGKEI 

       370        380 
LSNSGLEIIP AHDLADAASK IVEAI 

« Hide

References

[1]"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RML369-C.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000087 Genomic DNA. Translation: ABE05309.1.
RefSeqYP_538398.1. NC_007940.1.

3D structure databases

ProteinModelPortalQ1RH55.
SMRQ1RH55. Positions 1-385.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING336407.RBE_1228.

Proteomic databases

PRIDEQ1RH55.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE05309; ABE05309; RBE_1228.
GeneID3995496.
KEGGrbe:RBE_1228.
PATRIC17884076. VBIRicBel102610_1387.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0045.
HOGENOMHOG000007059.
KOK01903.
OMAKVVFMAS.
OrthoDBEOG644ZT0.

Enzyme and pathway databases

BioCycRBEL336407:GJCY-1265-MONOMER.
UniPathwayUPA00223; UER00999.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.261. 1 hit.
HAMAPMF_00558. Succ_CoA_beta.
InterProIPR011761. ATP-grasp.
IPR013650. ATP-grasp_succ-CoA_synth-type.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR005811. CoA_ligase.
IPR017866. Succ-CoA_synthase_bsu_CS.
IPR005809. Succ_CoA_synthase_bsu.
IPR016102. Succinyl-CoA_synth-like.
[Graphical view]
PANTHERPTHR11815. PTHR11815. 1 hit.
PfamPF08442. ATP-grasp_2. 1 hit.
PF00549. Ligase_CoA. 1 hit.
[Graphical view]
PIRSFPIRSF001554. SucCS_beta. 1 hit.
SUPFAMSSF52210. SSF52210. 1 hit.
TIGRFAMsTIGR01016. sucCoAbeta. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS01217. SUCCINYL_COA_LIG_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSUCC_RICBR
AccessionPrimary (citable) accession number: Q1RH55
Entry history
Integrated into UniProtKB/Swiss-Prot: February 20, 2007
Last sequence update: May 16, 2006
Last modified: May 14, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia bellii strain RML369-C

Rickettsia bellii (strain RML369-C): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways