Q1RGZ5 (DSB_RICBR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative protein-disulfide oxidoreductase RBE_1288
EC=1.8.-.-

Gene names

Ordered Locus Names:

RBE_1288

Organism

Rickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]

Taxonomic identifier

336407 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › belli group › Rickettsia bellii

Protein attributes

Sequence length	259 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May be required for disulfide bond formation in some proteins By similarity.
Subcellular location	Periplasm By similarity.
Sequence similarities	Belongs to the thioredoxin family. DsbA subfamily. Contains 1 thioredoxin domain.

Ontologies

Keywords
Cellular component	Periplasm
Domain	Redox-active center Signal
Molecular function	Oxidoreductase
PTM	Disulfide bond
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	cell redox homeostasis Inferred from electronic annotation. Source: InterPro
Cellular_component	periplasmic space Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 20	20	Potential
	Chain	21 – 259	239	Putative protein-disulfide oxidoreductase RBE_1288		PRO_0000259989
Regions
	Domain	47 – 251	205	Thioredoxin
Amino acid modifications
	Disulfide bond	104 ↔ 107		Redox-active Potential

Sequences

	Sequence		Length	Mass (Da)
	Q1RGZ5 [UniParc]. Last modified May 16, 2006. Version 1. Checksum: 2CDE8B088FB49701	FASTA	259	29,178
	10 20 30 40 50 60 MRNSFITLIF LLLLSGCSEE KEKVVEQESS ESITPAQAST SDENNNQTTE TTTPAVITPA 70 80 90 100 110 120 VQEQIEQKPE VKTFKVTFKI DENDMVLGNK DSKIVVVEYF SPTCPHCAYY HSTIFPELKQ 130 140 150 160 170 180 KYIDTNKIAY VTREFIATKQ DLDASILARC KGDINSFMLF HDIILKQQDK WSVSNKYREL 190 200 210 220 230 240 LTDIGQLGGV TPEEYKKCLS DDKITETLIA NTNFITKAPK FIGTPSFFVN GVQTENYSIN 250 SISAAIDKAI EESKNKIDL

References

[1]

"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens." Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D. PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RML369-C.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000087 Genomic DNA. Translation: ABE05369.1.
RefSeq	YP_538458.1. NC_007940.1.
3D structure databases
ProteinModelPortal	Q1RGZ5.
ModBase	Search...
Protein-protein interaction databases
STRING	336407.RBE_1288.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABE05369; ABE05369; RBE_1288.
GeneID	3995977.
KEGG	rbe:RBE_1288.
PATRIC	17884208. VBIRicBel102610_1452.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1651.
HOGENOM	HOG000272918.
OMA	AYYHQTI.
ProtClustDB	CLSK870708.
Enzyme and pathway databases
BioCyc	RBEL336407:GJCY-1326-MONOMER.
Family and domain databases
Gene3D	3.40.30.10. 1 hit.
InterPro	IPR012336. Thioredoxin-like_fold. IPR017937. Thioredoxin_CS. [Graphical view]
SUPFAM	SSF52833. Thiordxn-like_fd. 1 hit.
PROSITE	PS00194. THIOREDOXIN_1. 1 hit. PS51352. THIOREDOXIN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DSB_RICBR

Accession

Primary (citable) accession number: Q1RGZ5

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 14, 2006
Last sequence update:	May 16, 2006
Last modified:	May 1, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program