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Protein

GTPase Obg

Gene

obg

Organism
Rickettsia bellii (strain RML369-C)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.UniRule annotation

Cofactori

Mg2+UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi166 – 1738GTPUniRule annotation
Nucleotide bindingi212 – 2165GTPUniRule annotation
Nucleotide bindingi279 – 2824GTPUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: UniProtKB-HAMAP
  2. GTP binding Source: UniProtKB-HAMAP
  3. magnesium ion binding Source: InterPro
Complete GO annotation...

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciRBEL336407:GJCY-1362-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
GTPase ObgUniRule annotation
Alternative name(s):
GTP-binding protein ObgUniRule annotation
Gene namesi
Name:obgUniRule annotation
Ordered Locus Names:RBE_1324
OrganismiRickettsia bellii (strain RML369-C)
Taxonomic identifieri336407 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group
ProteomesiUP000001951: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 328328GTPase ObgPRO_0000386200Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi336407.RBE_1324.

Structurei

3D structure databases

ProteinModelPortaliQ1RGV9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini160 – 327168OBG-type GAdd
BLAST

Sequence similaritiesi

Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0536.
HOGENOMiHOG000019084.
KOiK03979.
OMAiAPKFAQP.
OrthoDBiEOG6H1Q1M.

Family and domain databases

Gene3Di2.70.210.12. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_01454. GTPase_Obg.
InterProiIPR014100. GTP-bd_Obg/CgtA.
IPR006074. GTP1-OBG_CS.
IPR006169. GTP1_OBG_dom.
IPR006073. GTP_binding_domain.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
[Graphical view]
PfamiPF01018. GTP1_OBG. 1 hit.
PF01926. MMR_HSR1. 1 hit.
[Graphical view]
PIRSFiPIRSF002401. GTP_bd_Obg/CgtA. 1 hit.
PRINTSiPR00326. GTP1OBG.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF82051. SSF82051. 1 hit.
TIGRFAMsiTIGR02729. Obg_CgtA. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS51710. G_OBG. 1 hit.
PS00905. GTP1_OBG. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1RGV9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNFIDEVKIY IKGGNGGNGC VSFHREKFID RGGPDGGDGG RGGSIIFRSN
60 70 80 90 100
HHLNTLVNYR YKQHFIADSG ENGKGSNKSG KSGKSLTLDV PIGTQIFAED
110 120 130 140 150
SDILLHDFTE DDQTFEIIKG GNGGLGNSHF KTSVNQAPRR RTEGEIAEEM
160 170 180 190 200
WVQLSLKLLS DVGLVGLPNA GKSTFLSVVS AAKPKIADYP FTTLVPNLGV
210 220 230 240 250
VYIDDEEFVI ADIPGLIEGA SQGHGLGDKF LKHIERCNVL IHLIDGSSED
260 270 280 290 300
VVADYNIVRT ELESYSDYLK DKTQIICLNK IDVLTDEEIA EKTTQLQKIT
310 320
GKEIFPISTY TNTGITKIIK LALQTIKD
Length:328
Mass (Da):35,849
Last modified:May 16, 2006 - v1
Checksum:iE7B74841DD9E23DE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000087 Genomic DNA. Translation: ABE05405.1.
RefSeqiWP_011477975.1. NC_007940.1.
YP_538494.1. NC_007940.1.

Genome annotation databases

EnsemblBacteriaiABE05405; ABE05405; RBE_1324.
GeneIDi3996132.
KEGGirbe:RBE_1324.
PATRICi17884292. VBIRicBel102610_1494.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000087 Genomic DNA. Translation: ABE05405.1.
RefSeqiWP_011477975.1. NC_007940.1.
YP_538494.1. NC_007940.1.

3D structure databases

ProteinModelPortaliQ1RGV9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi336407.RBE_1324.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABE05405; ABE05405; RBE_1324.
GeneIDi3996132.
KEGGirbe:RBE_1324.
PATRICi17884292. VBIRicBel102610_1494.

Phylogenomic databases

eggNOGiCOG0536.
HOGENOMiHOG000019084.
KOiK03979.
OMAiAPKFAQP.
OrthoDBiEOG6H1Q1M.

Enzyme and pathway databases

BioCyciRBEL336407:GJCY-1362-MONOMER.

Family and domain databases

Gene3Di2.70.210.12. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_01454. GTPase_Obg.
InterProiIPR014100. GTP-bd_Obg/CgtA.
IPR006074. GTP1-OBG_CS.
IPR006169. GTP1_OBG_dom.
IPR006073. GTP_binding_domain.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
[Graphical view]
PfamiPF01018. GTP1_OBG. 1 hit.
PF01926. MMR_HSR1. 1 hit.
[Graphical view]
PIRSFiPIRSF002401. GTP_bd_Obg/CgtA. 1 hit.
PRINTSiPR00326. GTP1OBG.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF82051. SSF82051. 1 hit.
TIGRFAMsiTIGR02729. Obg_CgtA. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS51710. G_OBG. 1 hit.
PS00905. GTP1_OBG. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
    Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
    PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RML369-C.

Entry informationi

Entry nameiOBG_RICBR
AccessioniPrimary (citable) accession number: Q1RGV9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 13, 2009
Last sequence update: May 16, 2006
Last modified: February 4, 2015
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia bellii strain RML369-C
    Rickettsia bellii (strain RML369-C): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.