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Q1RGV8 (CISY_RICBR) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Citrate synthase
EC=2.3.3.1
Gene names
Name:gltA
Ordered Locus Names:RBE_1325
OrganismRickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]
Taxonomic identifier336407 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › belli group ›

Protein attributes

Sequence length435 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Acetyl-CoA + H2O + oxaloacetate = citrate + CoA.

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 1/2.

Miscellaneous

Citrate synthase is found in nearly all cells capable of oxidative metabolism.

Sequence similarities

Belongs to the citrate synthase family.

Ontologies

Keywords
   Biological processTricarboxylic acid cycle
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcellular carbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

tricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: InterPro

   Molecular_functioncitrate (Si)-synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 435435Citrate synthase
PRO_0000273146

Sites

Active site3111 By similarity
Active site3701 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q1RGV8 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: 915B621AB5C5154F

FASTA43549,385
        10         20         30         40         50         60 
MTSENNNTEF AELKIRDKIF KLPILKASIG QDVIDISKVY SEADCFTYDP GFMSTASCRS 

        70         80         90        100        110        120 
TITYIDGDQG ILRHRGYDIK DLAEKSDFLE VAYLLIYGEL PNNKQYNDFT KKVAHHALVN 

       130        140        150        160        170        180 
ERLHYLFQTF CSSSHPMAIM LAAVGSLSAF YPDLLNFFKE ADYELTAIRM IAKIPTIAAM 

       190        200        210        220        230        240 
SYKYSIGQPF VYPDNSLDFT ENFLHMMFAT PCEKYKVNPV IKNALNKIFI LHADHEQNAS 

       250        260        270        280        290        300 
TSTVRIAGSS GANPFACVST GIASLWGPAH GGANEAVINM LKEIGSVENI PKYIAKAKDK 

       310        320        330        340        350        360 
NDNFRLMGFG HRVYKNYDPR AAVLKETCKE VLKELGQLDN NPLLQIAIEL EAIALKDEYF 

       370        380        390        400        410        420 
IERKLYPNVD FYSGIIYKAM GIPPQMFTVL FATARTVGWM AQWKEMHEDP EQKISRPRQL 

       430 
YTGQVHREYK TIKER

« Hide

References

[1]"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RML369-C.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000087 Genomic DNA. Translation: ABE05406.1.
RefSeqYP_538495.1. NC_007940.1.

3D structure databases

ProteinModelPortalQ1RGV8.
SMRQ1RGV8. Positions 17-435.
ModBaseSearch...

Protein-protein interaction databases

STRING336407.RBE_1325.

Proteomic databases

PRIDEQ1RGV8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE05406; ABE05406; RBE_1325.
GeneID3996133.
KEGGrbe:RBE_1325.
PATRIC17884294. VBIRicBel102610_1495.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0372.
HOGENOMHOG000021224.
KOK01647.
OMARVTHHTM.
ProtClustDBPRK05614.

Enzyme and pathway databases

BioCycRBEL336407:GJCY-1363-MONOMER.
UniPathwayUPA00223; UER00717.

Family and domain databases

Gene3D1.10.230.10. 1 hit.
1.10.580.10. 1 hit.
InterProIPR016142. Citrate_synth-like_lrg_a-sub.
IPR016143. Citrate_synth-like_sm_a-sub.
IPR002020. Citrate_synthase-like.
IPR016141. Citrate_synthase-like_core.
IPR019810. Citrate_synthase_AS.
IPR024176. Citrate_synthase_bac-typ.
IPR010953. Citrate_synthase_typ-II.
[Graphical view]
PANTHERPTHR11739. PTHR11739. 1 hit.
PfamPF00285. Citrate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001369. Citrate_synth. 1 hit.
PRINTSPR00143. CITRTSNTHASE.
SUPFAMSSF48256. Citrate_synthase_core. 1 hit.
TIGRFAMsTIGR01798. cit_synth_I. 1 hit.
PROSITEPS00480. CITRATE_SYNTHASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCISY_RICBR
AccessionPrimary (citable) accession number: Q1RGV8
Entry history
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: May 16, 2006
Last modified: May 1, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Rickettsia bellii strain RML369-C

Rickettsia bellii (strain RML369-C): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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