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Q1RGV8

- CISY_RICBR

UniProt

Q1RGV8 - CISY_RICBR

Protein

Citrate synthase

Gene

gltA

Organism
Rickettsia bellii (strain RML369-C)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 53 (01 Oct 2014)
      Sequence version 1 (16 May 2006)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Acetyl-CoA + H2O + oxaloacetate = citrate + CoA.PROSITE-ProRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei311 – 3111PROSITE-ProRule annotation
    Active sitei370 – 3701PROSITE-ProRule annotation

    GO - Molecular functioni

    1. citrate (Si)-synthase activity Source: InterPro

    GO - Biological processi

    1. cellular carbohydrate metabolic process Source: InterPro
    2. tricarboxylic acid cycle Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    Tricarboxylic acid cycle

    Enzyme and pathway databases

    BioCyciRBEL336407:GJCY-1363-MONOMER.
    UniPathwayiUPA00223; UER00717.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Citrate synthase (EC:2.3.3.16)
    Gene namesi
    Name:gltA
    Ordered Locus Names:RBE_1325
    OrganismiRickettsia bellii (strain RML369-C)
    Taxonomic identifieri336407 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group
    ProteomesiUP000001951: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 435435Citrate synthasePRO_0000273146Add
    BLAST

    Proteomic databases

    PRIDEiQ1RGV8.

    Interactioni

    Protein-protein interaction databases

    STRINGi336407.RBE_1325.

    Structurei

    3D structure databases

    ProteinModelPortaliQ1RGV8.
    SMRiQ1RGV8. Positions 17-435.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the citrate synthase family.Curated

    Phylogenomic databases

    eggNOGiCOG0372.
    HOGENOMiHOG000021224.
    KOiK01647.
    OMAiKETCDEV.
    OrthoDBiEOG6P8TP4.

    Family and domain databases

    Gene3Di1.10.230.10. 1 hit.
    1.10.580.10. 1 hit.
    InterProiIPR016142. Citrate_synth-like_lrg_a-sub.
    IPR016143. Citrate_synth-like_sm_a-sub.
    IPR002020. Citrate_synthase-like.
    IPR016141. Citrate_synthase-like_core.
    IPR019810. Citrate_synthase_AS.
    IPR024176. Citrate_synthase_bac-typ.
    IPR010953. Citrate_synthase_typ-I.
    [Graphical view]
    PANTHERiPTHR11739. PTHR11739. 1 hit.
    PfamiPF00285. Citrate_synt. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001369. Citrate_synth. 1 hit.
    PRINTSiPR00143. CITRTSNTHASE.
    SUPFAMiSSF48256. SSF48256. 1 hit.
    TIGRFAMsiTIGR01798. cit_synth_I. 1 hit.
    PROSITEiPS00480. CITRATE_SYNTHASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q1RGV8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTSENNNTEF AELKIRDKIF KLPILKASIG QDVIDISKVY SEADCFTYDP    50
    GFMSTASCRS TITYIDGDQG ILRHRGYDIK DLAEKSDFLE VAYLLIYGEL 100
    PNNKQYNDFT KKVAHHALVN ERLHYLFQTF CSSSHPMAIM LAAVGSLSAF 150
    YPDLLNFFKE ADYELTAIRM IAKIPTIAAM SYKYSIGQPF VYPDNSLDFT 200
    ENFLHMMFAT PCEKYKVNPV IKNALNKIFI LHADHEQNAS TSTVRIAGSS 250
    GANPFACVST GIASLWGPAH GGANEAVINM LKEIGSVENI PKYIAKAKDK 300
    NDNFRLMGFG HRVYKNYDPR AAVLKETCKE VLKELGQLDN NPLLQIAIEL 350
    EAIALKDEYF IERKLYPNVD FYSGIIYKAM GIPPQMFTVL FATARTVGWM 400
    AQWKEMHEDP EQKISRPRQL YTGQVHREYK TIKER 435
    Length:435
    Mass (Da):49,385
    Last modified:May 16, 2006 - v1
    Checksum:i915B621AB5C5154F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000087 Genomic DNA. Translation: ABE05406.1.
    RefSeqiYP_538495.1. NC_007940.1.

    Genome annotation databases

    EnsemblBacteriaiABE05406; ABE05406; RBE_1325.
    GeneIDi3996133.
    KEGGirbe:RBE_1325.
    PATRICi17884294. VBIRicBel102610_1495.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000087 Genomic DNA. Translation: ABE05406.1 .
    RefSeqi YP_538495.1. NC_007940.1.

    3D structure databases

    ProteinModelPortali Q1RGV8.
    SMRi Q1RGV8. Positions 17-435.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 336407.RBE_1325.

    Proteomic databases

    PRIDEi Q1RGV8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABE05406 ; ABE05406 ; RBE_1325 .
    GeneIDi 3996133.
    KEGGi rbe:RBE_1325.
    PATRICi 17884294. VBIRicBel102610_1495.

    Phylogenomic databases

    eggNOGi COG0372.
    HOGENOMi HOG000021224.
    KOi K01647.
    OMAi KETCDEV.
    OrthoDBi EOG6P8TP4.

    Enzyme and pathway databases

    UniPathwayi UPA00223 ; UER00717 .
    BioCyci RBEL336407:GJCY-1363-MONOMER.

    Family and domain databases

    Gene3Di 1.10.230.10. 1 hit.
    1.10.580.10. 1 hit.
    InterProi IPR016142. Citrate_synth-like_lrg_a-sub.
    IPR016143. Citrate_synth-like_sm_a-sub.
    IPR002020. Citrate_synthase-like.
    IPR016141. Citrate_synthase-like_core.
    IPR019810. Citrate_synthase_AS.
    IPR024176. Citrate_synthase_bac-typ.
    IPR010953. Citrate_synthase_typ-I.
    [Graphical view ]
    PANTHERi PTHR11739. PTHR11739. 1 hit.
    Pfami PF00285. Citrate_synt. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001369. Citrate_synth. 1 hit.
    PRINTSi PR00143. CITRTSNTHASE.
    SUPFAMi SSF48256. SSF48256. 1 hit.
    TIGRFAMsi TIGR01798. cit_synth_I. 1 hit.
    PROSITEi PS00480. CITRATE_SYNTHASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
      Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
      PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: RML369-C.

    Entry informationi

    Entry nameiCISY_RICBR
    AccessioniPrimary (citable) accession number: Q1RGV8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 23, 2007
    Last sequence update: May 16, 2006
    Last modified: October 1, 2014
    This is version 53 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Citrate synthase is found in nearly all cells capable of oxidative metabolism.

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. Rickettsia bellii strain RML369-C
      Rickettsia bellii (strain RML369-C): entries and gene names
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3