Q1RGT2 (RSMG_RICBR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosomal RNA small subunit methyltransferase G
EC=2.1.1.170

Alternative name(s):
16S rRNA 7-methylguanosine methyltransferase
Short name=16S rRNA m7G methyltransferase

Gene names

Name:	rsmG
Ordered Locus Names:	RBE_1351

Organism

Rickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]

Taxonomic identifier

336407 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › belli group › Rickettsia bellii

Protein attributes

Sequence length	192 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA By similarity. HAMAP-Rule MF_00074
Catalytic activity	S-adenosyl-L-methionine + guanine(527) in 16S rRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(527) in 16S rRNA. HAMAP-Rule MF_00074
Subcellular location	Cytoplasm Potential HAMAP-Rule MF_00074.
Sequence similarities	Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	rRNA (guanine-N7)-methylation Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	rRNA (guanine-N7-)-methyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 192	192	Ribosomal RNA small subunit methyltransferase G HAMAP-Rule MF_00074		PRO_0000274837
Regions
	Region	112 – 113	2	S-adenosyl-L-methionine binding By similarity
Sites
	Binding site	63	1	S-adenosyl-L-methionine; via carbonyl oxygen By similarity
	Binding site	68	1	S-adenosyl-L-methionine; via carbonyl oxygen By similarity
	Binding site	125	1	S-adenosyl-L-methionine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q1RGT2 [UniParc]. Last modified May 16, 2006. Version 1. Checksum: C4B71DA5A58AB646	FASTA	192	21,875
	10 20 30 40 50 60 MIDVPHEVIE KLQIFQDLVQ KWNKAINLIS ENSTQNFWKR HILDSLQLIQ YINDKEIHLV 70 80 90 100 110 120 DIGSGAGFPG IILSIAGVAS TSLIEADLRK CIFLEKAAKI SNNNIQIINQ RIEKTEISCN 130 140 150 160 170 180 ILTCRAFSNL NTIFDCTKNI SVQNKFLLPK GKSYLSEIKE ARKKWLFKCL INQSITSKES 190 KILEISDLTK II

References

[1]

"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens." Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D. PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RML369-C.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000087 Genomic DNA. Translation: ABE05432.1.
RefSeq	YP_538521.1. NC_007940.1.
3D structure databases
ProteinModelPortal	Q1RGT2.
ModBase	Search...
Protein-protein interaction databases
STRING	336407.RBE_1351.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABE05432; ABE05432; RBE_1351.
GeneID	3995779.
KEGG	rbe:RBE_1351.
PATRIC	17884352. VBIRicBel102610_1524.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0357.
HOGENOM	HOG000221015.
KO	K03501.
OMA	FHKGRDY.
ProtClustDB	PRK00107.
Enzyme and pathway databases
BioCyc	RBEL336407:GJCY-1389-MONOMER.
Family and domain databases
HAMAP	MF_00074. 16SrRNA_methyltr_G.
InterPro	IPR003682. rRNA_ssu_MeTfrase_G. [Graphical view]
Pfam	PF02527. GidB. 1 hit. [Graphical view]
PIRSF	PIRSF003078. GidB. 1 hit.
TIGRFAMs	TIGR00138. gidB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RSMG_RICBR

Accession

Primary (citable) accession number: Q1RGT2

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 6, 2007
Last sequence update:	May 16, 2006
Last modified:	May 1, 2013
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program