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Q1RGT2 (RSMG_RICBR) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribosomal RNA small subunit methyltransferase G

EC=2.1.1.170
Alternative name(s):
16S rRNA 7-methylguanosine methyltransferase
Short name=16S rRNA m7G methyltransferase
Gene names
Name:rsmG
Ordered Locus Names:RBE_1351
OrganismRickettsia bellii (strain RML369-C) [Complete proteome] [HAMAP]
Taxonomic identifier336407 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group

Protein attributes

Sequence length192 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically methylates the N7 position of guanine in position 527 of 16S rRNA By similarity. HAMAP-Rule MF_00074

Catalytic activity

S-adenosyl-L-methionine + guanine(527) in 16S rRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(527) in 16S rRNA. HAMAP-Rule MF_00074

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00074.

Sequence similarities

Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.

Ontologies

Keywords
   Biological processrRNA processing
   Cellular componentCytoplasm
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionrRNA (guanine-N7-)-methyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 192192Ribosomal RNA small subunit methyltransferase G HAMAP-Rule MF_00074
PRO_0000274837

Regions

Region112 – 1132S-adenosyl-L-methionine binding By similarity

Sites

Binding site631S-adenosyl-L-methionine; via carbonyl oxygen By similarity
Binding site681S-adenosyl-L-methionine; via carbonyl oxygen By similarity
Binding site1251S-adenosyl-L-methionine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q1RGT2 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: C4B71DA5A58AB646

FASTA19221,875
        10         20         30         40         50         60 
MIDVPHEVIE KLQIFQDLVQ KWNKAINLIS ENSTQNFWKR HILDSLQLIQ YINDKEIHLV 

        70         80         90        100        110        120 
DIGSGAGFPG IILSIAGVAS TSLIEADLRK CIFLEKAAKI SNNNIQIINQ RIEKTEISCN 

       130        140        150        160        170        180 
ILTCRAFSNL NTIFDCTKNI SVQNKFLLPK GKSYLSEIKE ARKKWLFKCL INQSITSKES 

       190 
KILEISDLTK II 

« Hide

References

[1]"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens."
Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.
PLoS Genet. 2:733-744(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RML369-C.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000087 Genomic DNA. Translation: ABE05432.1.
RefSeqYP_538521.1. NC_007940.1.

3D structure databases

ProteinModelPortalQ1RGT2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING336407.RBE_1351.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE05432; ABE05432; RBE_1351.
GeneID3995779.
KEGGrbe:RBE_1351.
PATRIC17884352. VBIRicBel102610_1524.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0357.
HOGENOMHOG000221015.
KOK03501.
OMAVESNARK.
OrthoDBEOG6HF639.

Enzyme and pathway databases

BioCycRBEL336407:GJCY-1389-MONOMER.

Family and domain databases

Gene3D3.40.50.150. 1 hit.
HAMAPMF_00074. 16SrRNA_methyltr_G.
InterProIPR003682. rRNA_ssu_MeTfrase_G.
IPR029063. SAM-dependent_MTases-like.
[Graphical view]
PfamPF02527. GidB. 1 hit.
[Graphical view]
PIRSFPIRSF003078. GidB. 1 hit.
SUPFAMSSF53335. SSF53335. 1 hit.
TIGRFAMsTIGR00138. gidB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRSMG_RICBR
AccessionPrimary (citable) accession number: Q1RGT2
Entry history
Integrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: May 16, 2006
Last modified: June 11, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia bellii strain RML369-C

Rickettsia bellii (strain RML369-C): entries and gene names