Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q1RFM2 (Q1RFM2_ECOUT) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Betaine aldehyde dehydrogenase HAMAP MF_00804
Short name=BADH HAMAP MF_00804
EC=1.2.1.8 HAMAP MF_00804
Gene names
Name:betB HAMAP MF_00804
Ordered Locus Names:UTI89_C0341
OrganismEscherichia coli (strain UTI89 / UPEC) [Complete proteome] [HAMAP] EMBL ABE05842.1
Taxonomic identifier364106 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length491 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Betaine aldehyde + NAD+ + H2O = betaine + NADH. HAMAP MF_00804

Pathway

Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1. HAMAP MF_00804

Sequence similarities

Belongs to the aldehyde dehydrogenase family. HAMAP MF_00804

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding230 – 2356NAD By similarity HAMAP MF_00804

Sites

Active site2531 By similarity HAMAP MF_00804
Active site2871 By similarity HAMAP MF_00804

Sequences

Sequence LengthMass (Da)Tools
Q1RFM2 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: 0DA8E8719CC6D7C1

FASTA49153,044
        10         20         30         40         50         60 
MMSRMAEQQL YIHGGYTSAT SGRTFETINP ANGNVLATVQ AAGREDVDRA VKSAQQGQKI 

        70         80         90        100        110        120 
WAAMTAMERS RILRRAVDIL RERNDELAKL ETLDTGKAYS ETSTVDIVTG ADVLEYYAGL 

       130        140        150        160        170        180 
IPALEGSQIP LRETSFVYTR REPLGVVAGI GAWNYPIQIA LWKSAPALAA GNAMIFKPSE 

       190        200        210        220        230        240 
VTPLTALKLA EIYSEAGLPD GVFNVLPGVG AETGQYLTDH PGIAKVSFTG GVASGKKVMA 

       250        260        270        280        290        300 
NSAASSLKEV TMELGGKSPL IVFDDADLDL AADITMMANF FSSGQVCTNG TRVFVPTKCK 

       310        320        330        340        350        360 
AAFEQKILAR VERIRAGDVF DPQTNFGPLV SFPHRDNVLR YIAKGIEEGA RVLCGGDVLK 

       370        380        390        400        410        420 
GDSFDNGAWV APTVFTDCSD DMTIVREEIF GPVMSILTYE SEDEVIRRAN DTDYGLAAGI 

       430        440        450        460        470        480 
VTADLNLAHR VIHQLEAGIC WINTWGESPA EMPVGGYKHS GIGRENGVMT LQSYTQVKSI 

       490 
QVEMAKFQSI F

« Hide

References

[1]"Identification of genes subject to positive selection in uropathogenic strains of Escherichia coli: a comparative genomics approach."
Chen S.L., Hung C.-S., Xu J., Reigstad C.S., Magrini V., Sabo A., Blasiar D., Bieri T., Meyer R.R., Ozersky P., Armstrong J.R., Fulton R.S., Latreille J.P., Spieth J., Hooton T.M., Mardis E.R., Hultgren S.J., Gordon J.I.
Proc. Natl. Acad. Sci. U.S.A. 103:5977-5982(2006) [PubMed: 16585510] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000243 Genomic DNA. Translation: ABE05842.1.
RefSeqYP_539373.1. NC_007946.1.

3D structure databases

ProteinModelPortalQ1RFM2.
SMRQ1RFM2. Positions 8-491.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ1RFM2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBESCT00000068986; EBESCP00000066464; EBESCG00000068033.
GeneID3990729.
GenomeReviewsGene locus UTI89_C0341 in contig CP000243_GR.
KEGGeci:UTI89_C0341.
PATRIC18450353. VBIEscCol42261_0449.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1012.
GeneTreeEBGT00050000009175.
HOGENOMHBG752218.
OMAGRENGLM.
ProtClustDBPRK13252.

Family and domain databases

HAMAPMF_00804. BADH.
[Tree]
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR011264. Betaine_Ald_DH.
[Graphical view]
Gene3DG3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit.
G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KOK00130.
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMsTIGR01804. BADH. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ1RFM2_ECOUT
AccessionPrimary (citable) accession number: Q1RFM2
Entry history
Integrated into UniProtKB/TrEMBL: May 16, 2006
Last sequence update: May 16, 2006
Last modified: December 14, 2011
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info