Q1REU8 (CITX_ECOUT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
EC=2.7.7.61

Alternative name(s):
Apo-ACP nucleodityltransferase
Holo-ACP synthase
Holo-citrate lyase synthase

Gene names

Name:	citX
Ordered Locus Names:	UTI89_C0616

Organism

Escherichia coli (strain UTI89 / UPEC) [Complete proteome] [HAMAP]

Taxonomic identifier

364106 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	183 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transfers 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A on a serine residue to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield holo-acyl carrier protein By similarity. HAMAP MF_00398
Catalytic activity	2'-(5-triphosphoribosyl)-3'-dephospho-CoA + citrate lyase apo-[acyl-carrier-protein] = citrate lyase holo-[acyl-carrier-protein] + diphosphate. HAMAP MF_00398
Sequence similarities	Belongs to the CitX family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	prosthetic group biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	holo-citrate lyase synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 183	183	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase HAMAP MF_00398		PRO_1000049603

Sequences

	Sequence		Length	Mass (Da)
	Q1REU8 [UniParc]. Last modified May 16, 2006. Version 1. Checksum: 6286C14BA1690764	FASTA	183	20,292
	10 20 30 40 50 60 MHLLPEFASH HAVSIPELLV SRDERQARQH AWLKRHPVPL VSFTVVAPGP IKDSEVTRRI 70 80 90 100 110 120 FNHGVTALRA LATKQGWQIQ EQAALVSASG PEGMLSIAAP ARDLKLATIE LEHSHPLGRL 130 140 150 160 170 180 WDIDVLTPEG DILSRRDYSL PPRRCLLCEQ SAAVCARGKT HQLTDLLNRM EALLNDVDAC NVN

References

[1]

"Identification of genes subject to positive selection in uropathogenic strains of Escherichia coli: a comparative genomics approach." Chen S.L., Hung C.-S., Xu J., Reigstad C.S., Magrini V., Sabo A., Blasiar D., Bieri T., Meyer R.R., Ozersky P., Armstrong J.R., Fulton R.S., Latreille J.P., Spieth J., Hooton T.M., Mardis E.R., Hultgren S.J., Gordon J.I. Proc. Natl. Acad. Sci. U.S.A. 103:5977-5982(2006) [PubMed: 16585510] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: UTI89 / UPEC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000243 Genomic DNA. Translation: ABE06116.1.
RefSeq	YP_539647.1. NC_007946.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q1REU8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000069424; EBESCP00000066902; EBESCG00000068471.
GeneID	3990940.
GenomeReviews	Gene locus UTI89_C0616 in contig CP000243_GR.
KEGG	eci:UTI89_C0616.
PATRIC	18450897. VBIEscCol42261_0719.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3697.
GeneTree	EBGT00050000009839.
HOGENOM	HBG698187.
OMA	PIGRLMD.
ProtClustDB	PRK01392.
Enzyme and pathway databases
BioCyc	ECOL364106:UTI89_C0616-MONOMER.
Family and domain databases
HAMAP	MF_00398. CitX. [Tree]
InterPro	IPR005551. CitX. [Graphical view]
KO	K05964.
Pfam	PF03802. CitX. 1 hit. [Graphical view]
TIGRFAMs	TIGR03124. Citrate_citX. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CITX_ECOUT

Accession

Primary (citable) accession number: Q1REU8

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	May 16, 2006
Last modified:	January 25, 2012
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program