Reviewed, UniProtKB/Swiss-Prot Q1R8T1 (EUTC_ECOUT)

Names and origin

Protein names

Recommended name:
    Ethanolamine ammonia-lyase light chain
    EC=4.3.1.7
Alternative name(s):
    Ethanolamine ammonia-lyase small subunit

Gene names

Name:	eutC
Ordered Locus Names:	UTI89_C2773

Organism

Escherichia coli (strain UTI89 / UPEC) [Complete proteome] [HAMAP]

Taxonomic identifier

364106 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	295 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Ethanolamine = acetaldehyde + NH3. HAMAP MF_00601
Cofactor	Adenosylcobalamin By similarity.
Pathway	Amine and polyamine degradation; ethanolamine degradation. HAMAP MF_00601
Subunit structure	Heterodimer of a small and a large subunit By similarity.
Sequence similarities	Belongs to the eutC family.

Ontologies

Keywords
Ligand	Cobalamin Cobalt
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	amino acid metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	cobalamin binding Inferred from electronic annotation. Source: UniProtKB-KW cobalt ion binding Inferred from electronic annotation. Source: UniProtKB-KW ethanolamine ammonia-lyase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 295	295	Ethanolamine ammonia-lyase light chain HAMAP MF_00601		PRO_1000025855

Sequences

	Sequence		Length	Mass (Da)
	Q1R8T1-1 [UniParc]. Last modified May 16, 2006. Version 1. Checksum: C7E87143B8E050E5	FASTA	295	31,782
	10 20 30 40 50 60 MDQKQIEEIV RSVMASMGQA APAPSEAKCA TTNCAAPVTS ESCALDLGSA EAKAWIGVEN 70 80 90 100 110 120 PHRADVLTEL RRSTVARVCT GRAGPRPRTQ ALLRFLADHS RSKDTVLKEV PEEWVKAQGL 130 140 150 160 170 180 LEVRSEISDK NLYLTRPDMG RRLCAEAVEA LKAQCVANPD VQVVISDGLS TDAITVNYEE 190 200 210 220 230 240 ILPPLMAGLK QAGLKVGTPF FVRYGRVKIE DQIGEILGAK VVILLVGERP GLGQSESLSC 250 260 270 280 290 YAVYSPRMAT TVEADRTCIS NIHQGGTPPV EAAAVIVDLA KRMLEQKASG INMTR

References

[1]

"Identification of genes subject to positive selection in uropathogenic strains of Escherichia coli: a comparative genomics approach." Chen S.L., Hung C.-S., Xu J., Reigstad C.S., Magrini V., Sabo A., Blasiar D., Bieri T., Meyer R.R., Ozersky P., Armstrong J.R., Fulton R.S., Latreille J.P., Spieth J., Hooton T.M., Mardis E.R., Hultgren S.J., Gordon J.I. Proc. Natl. Acad. Sci. U.S.A. 103:5977-5982(2006) [PubMed: 16585510] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000243 Genomic DNA. Translation: ABE08233.1.
RefSeq	YP_541764.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3989761.
GenomeReviews	Gene locus UTI89_C2773 in contig CP000243_GR.
KEGG	eci:UTI89_C2773.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q1R8T1.
OMA	Q1R8T1. LRFRADH.
Enzyme and pathway databases
BioCyc	ECOL364106:UTI89_C2773-MON.
Family and domain databases
HAMAP	MF_00601. [Tree]
InterPro	IPR009246. EutC. [Graphical view]
Pfam	PF05985. EutC. 1 hit. [Graphical view]
PIRSF	PIRSF018982. EutC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

EUTC_ECOUT

Accession

Primary (citable) accession number: Q1R8T1

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	May 16, 2006
Last modified:	June 16, 2009
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)