ID   KDUI_ECOUT              Reviewed;         278 AA.
AC   Q1R7G9;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2006, sequence version 1.
DT   16-JUN-2009, entry version 21.
DE   RecName: Full=4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase;
DE            EC=5.3.1.17;
DE   AltName: Full=5-keto-4-deoxyuronate isomerase;
DE   AltName: Full=DKI isomerase;
GN   Name=kduI; OrderedLocusNames=UTI89_C3246;
OS   Escherichia coli (strain UTI89 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=364106;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16585510; DOI=10.1073/pnas.0600938103;
RA   Chen S.L., Hung C.-S., Xu J., Reigstad C.S., Magrini V., Sabo A.,
RA   Blasiar D., Bieri T., Meyer R.R., Ozersky P., Armstrong J.R.,
RA   Fulton R.S., Latreille J.P., Spieth J., Hooton T.M., Mardis E.R.,
RA   Hultgren S.J., Gordon J.I.;
RT   "Identification of genes subject to positive selection in
RT   uropathogenic strains of Escherichia coli: a comparative genomics
RT   approach.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:5977-5982(2006).
CC   -!- CATALYTIC ACTIVITY: 4-deoxy-L-threo-5-hexosulose uronate = 3-
CC       deoxy-D-glycero-2,5-hexodiulosonate.
CC   -!- PATHWAY: Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-
CC       D-gluconic acid from pectin: step 4/5.
CC   -!- SUBUNIT: Homohexamer (By similarity).
CC   -!- SIMILARITY: Belongs to the kduI family.
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DR   EMBL; CP000243; ABE08695.1; -; Genomic_DNA.
DR   RefSeq; YP_542226.1; -.
DR   SMR; Q1R7G9; 1-277.
DR   GeneID; 3994152; -.
DR   GenomeReviews; CP000243_GR; UTI89_C3246.
DR   KEGG; eci:UTI89_C3246; -.
DR   HOGENOM; Q1R7G9; -.
DR   OMA; Q1R7G9; QAVISPP.
DR   BioCyc; ECOL364106:UTI89_C3246-MON; -.
DR   GO; GO:0008697; F:4-deoxy-L-threo-5-hexosulose-uronate ketol-...; IEA:HAMAP.
DR   GO; GO:0045490; P:pectin catabolic process; IEA:InterPro.
DR   HAMAP; MF_00687; -; 1.
DR   InterPro; IPR007045; KduI.
DR   Pfam; PF04962; KduI; 1.
DR   PIRSF; PIRSF006625; KduI; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Isomerase.
FT   CHAIN         1    278       4-deoxy-L-threo-5-hexosulose-uronate
FT                                ketol-isomerase.
FT                                /FTId=PRO_1000045083.
SQ   SEQUENCE   278 AA;  31076 MW;  7AF3DD98DE74D597 CRC64;
     MDVRQSIHSA HAKTLDTQGL RNEFLVEKVF VADEYTMVYS HIDRIIVGGI MPVTKTVSVG
     GEVGKQLGVS YFLERRELGV INIGGAGTIT VDGQCYEIGH RDALYVGKGA KEVVFASIDT
     ATPAKFYYNC APAHTTYPTK KVTPDEVSPV TLGDNLTSNR RTINKYFVPD VLETCQLSMG
     LTELAPGNLW NTMPCHTHER RMEVYFYFNM DDDACVFHMM GQPQETRHIV MHNEQAVISP
     SWSIHSGVGT KAYTFIWGMV GENQVFDDMD HVAVKDLR
//