Reviewed, UniProtKB/Swiss-Prot Q1R7G9 (KDUI_ECOUT)

Names and origin

Protein names

Recommended name:
    4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
    EC=5.3.1.17
Alternative name(s):
    5-keto-4-deoxyuronate isomerase
    DKI isomerase

Gene names

Name:	kduI
Ordered Locus Names:	UTI89_C3246

Organism

Escherichia coli (strain UTI89 / UPEC) [Complete proteome] [HAMAP]

Taxonomic identifier

364106 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	278 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	4-deoxy-L-threo-5-hexosulose uronate = 3-deoxy-D-glycero-2,5-hexodiulosonate. HAMAP MF_00687
Pathway	Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconic acid from pectin: step 4/5. HAMAP MF_00687
Subunit structure	Homohexamer By similarity.
Sequence similarities	Belongs to the kduI family.

Ontologies

Keywords
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pectin catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 278	278	4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase HAMAP MF_00687		PRO_1000045083

Sequences

	Sequence		Length	Mass (Da)
	Q1R7G9-1 [UniParc]. Last modified May 16, 2006. Version 1. Checksum: 7AF3DD98DE74D597	FASTA	278	31,076
	10 20 30 40 50 60 MDVRQSIHSA HAKTLDTQGL RNEFLVEKVF VADEYTMVYS HIDRIIVGGI MPVTKTVSVG 70 80 90 100 110 120 GEVGKQLGVS YFLERRELGV INIGGAGTIT VDGQCYEIGH RDALYVGKGA KEVVFASIDT 130 140 150 160 170 180 ATPAKFYYNC APAHTTYPTK KVTPDEVSPV TLGDNLTSNR RTINKYFVPD VLETCQLSMG 190 200 210 220 230 240 LTELAPGNLW NTMPCHTHER RMEVYFYFNM DDDACVFHMM GQPQETRHIV MHNEQAVISP 250 260 270 SWSIHSGVGT KAYTFIWGMV GENQVFDDMD HVAVKDLR

References

[1]

"Identification of genes subject to positive selection in uropathogenic strains of Escherichia coli: a comparative genomics approach." Chen S.L., Hung C.-S., Xu J., Reigstad C.S., Magrini V., Sabo A., Blasiar D., Bieri T., Meyer R.R., Ozersky P., Armstrong J.R., Fulton R.S., Latreille J.P., Spieth J., Hooton T.M., Mardis E.R., Hultgren S.J., Gordon J.I. Proc. Natl. Acad. Sci. U.S.A. 103:5977-5982(2006) [PubMed: 16585510] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000243 Genomic DNA. Translation: ABE08695.1.
RefSeq	YP_542226.1.
3D structure databases
SMR	Q1R7G9. Positions 1-277.
ModBase	Search...
Genome annotation databases
GeneID	3994152.
GenomeReviews	Gene locus UTI89_C3246 in contig CP000243_GR.
KEGG	eci:UTI89_C3246.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q1R7G9.
OMA	Q1R7G9. QAVISPP.
Enzyme and pathway databases
BioCyc	ECOL364106:UTI89_C3246-MON.
Family and domain databases
HAMAP	MF_00687. [Tree]
InterPro	IPR007045. KduI. [Graphical view]
Pfam	PF04962. KduI. 1 hit. [Graphical view]
PIRSF	PIRSF006625. KduI. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KDUI_ECOUT

Accession

Primary (citable) accession number: Q1R7G9

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	May 16, 2006
Last modified:	June 16, 2009
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)