Q1R6L2 (Q1R6L2_ECOUT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
2-hydroxy-3-oxopropionate reductase EMBL ABE09002.1
EC=1.1.1.60 EMBL ABE09002.1

Gene names

Name:	yhaE EMBL ABE09002.1
Ordered Locus Names:	UTI89_C3556

Organism

Escherichia coli (strain UTI89 / UPEC) [Complete proteome] [HAMAP] EMBL ABE09002.1

Taxonomic identifier

364106 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	299 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL ABE09002.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glyoxylate metabolic process Inferred from electronic annotation. Source: InterPro pentose-phosphate shunt Inferred from electronic annotation. Source: InterPro valine metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-hydroxy-3-oxopropionate reductase activity Inferred from electronic annotation. Source: EC 3-hydroxyisobutyrate dehydrogenase activity Inferred from electronic annotation. Source: InterPro coenzyme binding Inferred from electronic annotation. Source: InterPro nucleotide binding Inferred from electronic annotation. Source: InterPro phosphogluconate dehydrogenase (decarboxylating) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q1R6L2 [UniParc]. Last modified May 16, 2006. Version 1. Checksum: 08E65F7849754566	FASTA	299	31,049
	10 20 30 40 50 60 MIDMTMKVGF IGLGIMGKPM SKNLLKAGYS LVVADRNPEA IADVIAAGAE TASTAKAIAE 70 80 90 100 110 120 QCDVIITMLP NSPHVKEVAL GENGIIEGAK PGTVLIDMSS IAPLASREIS EALKAKGIDM 130 140 150 160 170 180 LDAPVSGGEP KAIDGTLSVM VGGDKAIFDK YYDLMKAMAG SVVHTGEIGA GNVTKLANQV 190 200 210 220 230 240 IVALNIAAMS EALTLATKAG VNPDLVYQAI RGGLAGSTVL DAKAPMVMDR NFKPGFRIDL 250 260 270 280 290 HIKDLANALD TSHGVGAQLP LTAAVMEMMQ ALRADGLGMA DHSALACYYE KLAKVEVTR

References

[1]

"Identification of genes subject to positive selection in uropathogenic strains of Escherichia coli: a comparative genomics approach." Chen S.L., Hung C.-S., Xu J., Reigstad C.S., Magrini V., Sabo A., Blasiar D., Bieri T., Meyer R.R., Ozersky P., Armstrong J.R., Fulton R.S., Latreille J.P., Spieth J., Hooton T.M., Mardis E.R., Hultgren S.J., Gordon J.I. Proc. Natl. Acad. Sci. U.S.A. 103:5977-5982(2006) [PubMed: 16585510] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000243 Genomic DNA. Translation: ABE09002.1.
RefSeq	YP_542533.2. NC_007946.1.
3D structure databases
ProteinModelPortal	Q1R6L2.
SMR	Q1R6L2. Positions 6-299.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1R6L2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000066653; EBESCP00000064131; EBESCG00000065700.
GeneID	3990327.
GenomeReviews	Gene locus UTI89_C3556 in contig CP000243_GR.
KEGG	eci:UTI89_C3556.
PATRIC	18456612. VBIEscCol42261_3522.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2084.
GeneTree	EBGT00050000009837.
HOGENOM	HBG729179.
OMA	WSRRRES.
ProtClustDB	PRK11559.
Family and domain databases
InterPro	IPR002204. 3-OH-isobutyrate_DH-rel_CS. IPR015815. 3hydroxyacid_DH/Rdtase. IPR008927. 6-PGluconate_DH_C-like. IPR006115. 6PGDH_NADP-bd. IPR013328. DH_multihelical. IPR016040. NAD(P)-bd_dom. IPR006398. Tartro_sem_red. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. G3DSA:1.10.1040.10. Opine_DH. 1 hit.
KO	K00042.
PANTHER	PTHR22981. 3hydroxy_acid_DH. 1 hit.
Pfam	PF03446. NAD_binding_2. 1 hit. [Graphical view]
SUPFAM	SSF48179. 6DGDH_C_like. 1 hit.
TIGRFAMs	TIGR01505. Tartro_sem_red. 1 hit.
PROSITE	PS00895. 3_HYDROXYISOBUT_DH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q1R6L2_ECOUT

Accession

Primary (citable) accession number: Q1R6L2

Entry history

Integrated into UniProtKB/TrEMBL:	May 16, 2006
Last sequence update:	May 16, 2006
Last modified:	December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)