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Protein

Glutamate decarboxylase

Gene

gadA

Organism
Escherichia coli (strain UTI89 / UPEC)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylaseUniRule annotation, Lyase
LigandPyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Name:gadAImported
Ordered Locus Names:UTI89_C4049Imported
OrganismiEscherichia coli (strain UTI89 / UPEC)Imported
Taxonomic identifieri364106 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000001952 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei297N6-(pyridoxal phosphate)lysineUniRule annotation1

Structurei

3D structure databases

ProteinModelPortaliQ1R586
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000070228
KOiK01580
OMAiFTTSVYG

Family and domain databases

Gene3Di3.40.640.10, 1 hit
InterProiView protein in InterPro
IPR010107 Glutamate_decarboxylase
IPR002129 PyrdxlP-dep_de-COase
IPR015424 PyrdxlP-dep_Trfase
IPR015421 PyrdxlP-dep_Trfase_major
IPR021115 Pyridoxal-P_BS
PANTHERiPTHR43321 PTHR43321, 1 hit
PfamiView protein in Pfam
PF00282 Pyridoxal_deC, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
TIGRFAMsiTIGR01788 Glu-decarb-GAD, 1 hit
PROSITEiView protein in PROSITE
PS00392 DDC_GAD_HDC_YDC, 1 hit

Sequencei

Sequence statusi: Complete.

Q1R586-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPLRINPTF LLPSNKFKEF EMDQKLLTDF RSELLDSRFG AKAISTIAES
60 70 80 90 100
KRFPLHEMRD DVAFQIINDE LYLDGNARQN LATFCQTWDD ENVHKLMDLS
110 120 130 140 150
INKNWIDKEE YPQSAAIDLR CVNMVADLWH APAPKNGQAV GTNTIGSSEA
160 170 180 190 200
CMLGGMAMKW RWRKRMEAAG KPTNKPNLVC GPVQICWHKF ARYWDVELRE
210 220 230 240 250
IPMRPGQLFM DPKRMIEACD ENTIGVVPTF GVTYTGNYEF PQPLHDALDK
260 270 280 290 300
FQADTGIDID MHIDAASGGF LAPFVAPDIV WDFRLPRVKS ISASGHKFGL
310 320 330 340 350
APLGCGWVIW RDEEALPQEL VFNVDYLGGQ IGTFAINFSR PAGQVIAQYY
360 370 380 390 400
EFLRLGREGY TKVQNASYQV AAYLADEIAK LGPYEFICTG RPDEGIPAVC
410 420 430 440 450
FKLKDGEDPG YTLYDLSERL RLRGWQVPAF TLGGEATDIV VMRIMCRRGF
460 470 480
EMDFAELLLE DYKASLKYLS DHPKLQGIAQ QNSFKHT
Length:487
Mass (Da):55,201
Last modified:May 16, 2006 - v1
Checksum:iDF925137BA525680
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000243 Genomic DNA Translation: ABE09478.1

Genome annotation databases

EnsemblBacteriaiABE09478; ABE09478; UTI89_C4049
KEGGieci:UTI89_C4049

Similar proteinsi

Entry informationi

Entry nameiQ1R586_ECOUT
AccessioniPrimary (citable) accession number: Q1R586
Entry historyiIntegrated into UniProtKB/TrEMBL: May 16, 2006
Last sequence update: May 16, 2006
Last modified: April 25, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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