Q1R586 (Q1R586_ECOUT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glutamate decarboxylase alpha EMBL ABE09478.1
EC=4.1.1.15 EMBL ABE09478.1

Gene names

Name:	gadA EMBL ABE09478.1
Ordered Locus Names:	UTI89_C4049 EMBL ABE09478.1

Organism

Escherichia coli (strain UTI89 / UPEC) [Complete proteome] [HAMAP] EMBL ABE09478.1

Taxonomic identifier

364106 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	487 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000382
Sequence similarities	Belongs to the group II decarboxylase family. RuleBase RU000382

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000382
Molecular function	Lyase RuleBase RU000382 EMBL ABE09478.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glutamate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	glutamate decarboxylase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q1R586 [UniParc]. Last modified May 16, 2006. Version 1. Checksum: DF925137BA525680	FASTA	487	55,201
	10 20 30 40 50 60 MLPLRINPTF LLPSNKFKEF EMDQKLLTDF RSELLDSRFG AKAISTIAES KRFPLHEMRD 70 80 90 100 110 120 DVAFQIINDE LYLDGNARQN LATFCQTWDD ENVHKLMDLS INKNWIDKEE YPQSAAIDLR 130 140 150 160 170 180 CVNMVADLWH APAPKNGQAV GTNTIGSSEA CMLGGMAMKW RWRKRMEAAG KPTNKPNLVC 190 200 210 220 230 240 GPVQICWHKF ARYWDVELRE IPMRPGQLFM DPKRMIEACD ENTIGVVPTF GVTYTGNYEF 250 260 270 280 290 300 PQPLHDALDK FQADTGIDID MHIDAASGGF LAPFVAPDIV WDFRLPRVKS ISASGHKFGL 310 320 330 340 350 360 APLGCGWVIW RDEEALPQEL VFNVDYLGGQ IGTFAINFSR PAGQVIAQYY EFLRLGREGY 370 380 390 400 410 420 TKVQNASYQV AAYLADEIAK LGPYEFICTG RPDEGIPAVC FKLKDGEDPG YTLYDLSERL 430 440 450 460 470 480 RLRGWQVPAF TLGGEATDIV VMRIMCRRGF EMDFAELLLE DYKASLKYLS DHPKLQGIAQ QNSFKHT

References

[1]

"Identification of genes subject to positive selection in uropathogenic strains of Escherichia coli: a comparative genomics approach." Chen S.L., Hung C.S., Xu J., Reigstad C.S., Magrini V., Sabo A., Blasiar D., Bieri T., Meyer R.R., Ozersky P., Armstrong J.R., Fulton R.S., Latreille J.P., Spieth J., Hooton T.M., Mardis E.R., Hultgren S.J., Gordon J.I. Proc. Natl. Acad. Sci. U.S.A. 103:5977-5982(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: UTI89 / UPEC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000243 Genomic DNA. Translation: ABE09478.1.
RefSeq	YP_543009.1. NC_007946.1.
3D structure databases
ProteinModelPortal	Q1R586.
SMR	Q1R586. Positions 25-473.
ModBase	Search...
Protein-protein interaction databases
STRING	364106.UTI89_C4049.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABE09478; ABE09478; UTI89_C4049.
GeneID	3991128.
KEGG	eci:UTI89_C4049.
PATRIC	18457527. VBIEscCol42261_3962.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0076.
HOGENOM	HOG000070228.
KO	K01580.
OMA	IELREVP.
ProtClustDB	CLSK880040.
Enzyme and pathway databases
BioCyc	ECOL364106:GHPQ-4012-MONOMER.
Family and domain databases
Gene3D	3.40.640.10. 1 hit.
InterPro	IPR010107. Glutamate_decarboxylase. IPR002129. PyrdxlP-dep_de-COase. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR021115. Pyridoxal-P_BS. [Graphical view]
PANTHER	PTHR11999:SF1. PTHR11999:SF1. 1 hit.
Pfam	PF00282. Pyridoxal_deC. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01788. Glu-decarb-GAD. 1 hit.
PROSITE	PS00392. DDC_GAD_HDC_YDC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q1R586_ECOUT

Accession

Primary (citable) accession number: Q1R586

Entry history

Integrated into UniProtKB/TrEMBL:	May 16, 2006
Last sequence update:	May 16, 2006
Last modified:	May 29, 2013
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)