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Protein
Submitted name:

Alpha-amylase

Gene

malS

Organism
Escherichia coli (strain UTI89 / UPEC)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. alpha-amylase activity Source: UniProtKB-EC
  2. calcium ion binding Source: InterPro

GO - Biological processi

  1. alpha-glucan catabolic process Source: InterPro
  2. cellular oligosaccharide catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseImported, Hydrolase

Enzyme and pathway databases

BioCyciECOL364106:GHPQ-4075-MONOMER.

Protein family/group databases

CAZyiGH13. Glycoside Hydrolase Family 13.

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-amylaseImported (EC:3.2.1.1Imported)
Gene namesi
Name:malSImported
Ordered Locus Names:UTI89_C4113Imported
OrganismiEscherichia coli (strain UTI89 / UPEC)Imported
Taxonomic identifieri364106 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000001952 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. periplasmic space Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi364106.UTI89_C4113.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0366.
HOGENOMiHOG000273912.
KOiK01176.
OMAiFNWHNAT.
OrthoDBiEOG65QWH3.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR014635. A_amylase_MalS.
IPR015902. Glyco_hydro_13.
IPR006047. Glyco_hydro_13_cat_dom.
IPR006589. Glyco_hydro_13_sub_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
[Graphical view]
PIRSFiPIRSF036917. Alph_amls_MalS. 1 hit.
SMARTiSM00642. Aamy. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 2 hits.

Sequencei

Sequence statusi: Complete.

Q1R523-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLAACFLTL LPGFAVAASW TSPGFPAFSE QGTGTFVSHA QLPKGTRPLT
60 70 80 90 100
LNFDQQCWQP ADAIKLNQML SLQPCSNTPP QWRLFRDGEY TLQLDTRSGT
110 120 130 140 150
PTLMISLQNT VEPVASLVRE CPKWDGLPLT LDVSATFAEG AAVRDYYSQQ
160 170 180 190 200
IAIVKNGQIT LQPAATSNGL LLLERAETDT SAPFDWHNAT VYFVLTDRFE
210 220 230 240 250
NGDPSNDQSY GRHKDGMAEI GTFHGGDLRG LTNKLDYLQQ LGVNALWISA
260 270 280 290 300
PFEQIHGWVG GGTKGDFPHY AYHGYYTQDW TNLDANMGSE ADLRTLVDSA
310 320 330 340 350
HQRGIRILFD IVMNHTGYAT LADMQEYQFG ALYLSGDELK KTLGERWSDW
360 370 380 390 400
KPAAGQTWHS FNDYINFSDK TGWDKWWGKN WIRTDIGDYD NPGFDDLTMS
410 420 430 440 450
LAFLPDIKTE STTASGLPVF YKNKTDTHAK VIDGFTPRDY LTHWLSQWVR
460 470 480 490 500
DYGIDGFRVD TAKHVELPAW QQLKTEASAA LREWKKANPD KALDDKPFWM
510 520 530 540 550
TGEAWGHGVM QSDYYRHGFD AMINFDYQEQ AAKAVDCLAQ MDTTWQQMAE
560 570 580 590 600
KLQDFNVLSY LSSHDTRLFR EGGDKAAELL LLAPGAVQIF YGDESSRPFG
610 620 630 640 650
PTGSDPLQGT RSDMNWQDVS GKSAASVAHW QKISQFRARH PAIGAGKQTT
660 670
LSLKQGYGFV REHGDDKVLV IWAGQQ
Length:676
Mass (Da):75,772
Last modified:May 16, 2006 - v1
Checksum:iC1E560649F274D34
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000243 Genomic DNA. Translation: ABE09541.1.
RefSeqiYP_543072.1. NC_007946.1.

Genome annotation databases

EnsemblBacteriaiABE09541; ABE09541; UTI89_C4113.
KEGGieci:UTI89_C4113.
PATRICi18457657. VBIEscCol42261_4026.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000243 Genomic DNA. Translation: ABE09541.1.
RefSeqiYP_543072.1. NC_007946.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi364106.UTI89_C4113.

Protein family/group databases

CAZyiGH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABE09541; ABE09541; UTI89_C4113.
KEGGieci:UTI89_C4113.
PATRICi18457657. VBIEscCol42261_4026.

Phylogenomic databases

eggNOGiCOG0366.
HOGENOMiHOG000273912.
KOiK01176.
OMAiFNWHNAT.
OrthoDBiEOG65QWH3.

Enzyme and pathway databases

BioCyciECOL364106:GHPQ-4075-MONOMER.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR014635. A_amylase_MalS.
IPR015902. Glyco_hydro_13.
IPR006047. Glyco_hydro_13_cat_dom.
IPR006589. Glyco_hydro_13_sub_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
[Graphical view]
PIRSFiPIRSF036917. Alph_amls_MalS. 1 hit.
SMARTiSM00642. Aamy. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 2 hits.
ProtoNetiSearch...

Publicationsi

  1. "Identification of genes subject to positive selection in uropathogenic strains of Escherichia coli: a comparative genomics approach."
    Chen S.L., Hung C.-S., Xu J., Reigstad C.S., Magrini V., Sabo A., Blasiar D., Bieri T., Meyer R.R., Ozersky P., Armstrong J.R., Fulton R.S., Latreille J.P., Spieth J., Hooton T.M., Mardis E.R., Hultgren S.J., Gordon J.I.
    Proc. Natl. Acad. Sci. U.S.A. 103:5977-5982(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: UTI89 / UPECImported.

Entry informationi

Entry nameiQ1R523_ECOUT
AccessioniPrimary (citable) accession number: Q1R523
Entry historyi
Integrated into UniProtKB/TrEMBL: May 16, 2006
Last sequence update: May 16, 2006
Last modified: April 1, 2015
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.