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Protein
Submitted name:

PTS system, glucose-specific IIBC component

Gene

UTI89_C4399

Organism
Escherichia coli (strain UTI89 / UPEC)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

Protein EIIB N(pi)-phospho-L-histidine/cysteine + sugar = protein EIIB + sugar phosphate.SAAS annotation

GO - Molecular functioni

  1. glucose transmembrane transporter activity Source: InterPro
  2. kinase activity Source: UniProtKB-KW
  3. protein-N(PI)-phosphohistidine-sugar phosphotransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. phosphoenolpyruvate-dependent sugar phosphotransferase system Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotation, Transferase

Keywords - Biological processi

Phosphotransferase systemSAAS annotation, Sugar transportSAAS annotation, Transport

Enzyme and pathway databases

BioCyciECOL364106:GHPQ-4358-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
PTS system, glucose-specific IIBC componentImported (EC:2.7.1.69Imported)
Gene namesi
Ordered Locus Names:UTI89_C4399Imported
OrganismiEscherichia coli (strain UTI89 / UPEC)Imported
Taxonomic identifieri364106 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000001952 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Interactioni

Protein-protein interaction databases

STRINGi364106.UTI89_C4399.

Structurei

3D structure databases

ProteinModelPortaliQ1R498.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains PTS EIIB type-1 domain.SAAS annotation
Contains PTS EIIC type-1 domain.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiCOG1263.
HOGENOMiHOG000250993.
KOiK02764.
K02765.
OMAiSFNGYQT.
OrthoDBiEOG6FFS9V.

Family and domain databases

Gene3Di3.30.1360.60. 1 hit.
InterProiIPR018113. PTrfase_EIIB_Cys.
IPR003352. PTS_EIIC.
IPR013013. PTS_EIIC_1.
IPR001996. PTS_IIB_1.
IPR011299. PTS_IIBC_glc.
[Graphical view]
PfamiPF00367. PTS_EIIB. 1 hit.
PF02378. PTS_EIIC. 1 hit.
[Graphical view]
SUPFAMiSSF55604. SSF55604. 1 hit.
TIGRFAMsiTIGR00826. EIIB_glc. 1 hit.
TIGR02002. PTS-II-BC-glcB. 1 hit.
PROSITEiPS51098. PTS_EIIB_TYPE_1. 1 hit.
PS01035. PTS_EIIB_TYPE_1_CYS. 1 hit.
PS51103. PTS_EIIC_TYPE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1R498-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKKITSLFN FKKLQKFSSA LMLPIAILPA AGLILAIGIS FNIELLANCG
60 70 80 90 100
GLIFANLPLL FCVGIVIGLT GDGSSSLSAI ISYMIMNATM GTQLGITAES
110 120 130 140 150
VAASNGDYAM ILGVPTLQTG VFGGLIVAIF VYLLYTRFHN IELPQFLGFF
160 170 180 190 200
GGKRFVPIIT AVAAIIVGYL LPWLWIPVQK GLASLSTLVT SGHNANFAAF
210 220 230 240 250
IYAVGERSLI PFGLHHIWNV PFYYNFGDYM TKSGQLVTGD IPVFFAQLRD
260 270 280 290 300
GVPLTAGLFM TGRFPIMMFA LPAAALAMYQ EAKPERKALI KGLLLSGALT
310 320 330 340 350
TFVTGITEPL EYAFLFAAPV LYIIHIFLYA TSFVLMNILN VHIGHPFAGG
360 370 380 390 400
LIDFVLNGVM PNRTPWYLVF LAGAGYAAIY YTVFRVLIRK LNLKTPGRED
410 420 430 440 450
EEIAVATTLT REERPYQIIE AVGGFDNIED VDACATRLRL ALVDDKKVNE
460 470 480 490 500
KRLKELGAAG LVKLGDGGVQ VIFGGKSQIL RDEIKTVMSR PRPTEMTVAC

AN
Length:502
Mass (Da):54,520
Last modified:May 16, 2006 - v1
Checksum:i479BCB7EBDE8AC13
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000243 Genomic DNA. Translation: ABE09816.1.
RefSeqiYP_543347.1. NC_007946.1.

Genome annotation databases

EnsemblBacteriaiABE09816; ABE09816; UTI89_C4399.
KEGGieci:UTI89_C4399.
PATRICi18458206. VBIEscCol42261_4289.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000243 Genomic DNA. Translation: ABE09816.1.
RefSeqiYP_543347.1. NC_007946.1.

3D structure databases

ProteinModelPortaliQ1R498.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi364106.UTI89_C4399.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABE09816; ABE09816; UTI89_C4399.
KEGGieci:UTI89_C4399.
PATRICi18458206. VBIEscCol42261_4289.

Phylogenomic databases

eggNOGiCOG1263.
HOGENOMiHOG000250993.
KOiK02764.
K02765.
OMAiSFNGYQT.
OrthoDBiEOG6FFS9V.

Enzyme and pathway databases

BioCyciECOL364106:GHPQ-4358-MONOMER.

Family and domain databases

Gene3Di3.30.1360.60. 1 hit.
InterProiIPR018113. PTrfase_EIIB_Cys.
IPR003352. PTS_EIIC.
IPR013013. PTS_EIIC_1.
IPR001996. PTS_IIB_1.
IPR011299. PTS_IIBC_glc.
[Graphical view]
PfamiPF00367. PTS_EIIB. 1 hit.
PF02378. PTS_EIIC. 1 hit.
[Graphical view]
SUPFAMiSSF55604. SSF55604. 1 hit.
TIGRFAMsiTIGR00826. EIIB_glc. 1 hit.
TIGR02002. PTS-II-BC-glcB. 1 hit.
PROSITEiPS51098. PTS_EIIB_TYPE_1. 1 hit.
PS01035. PTS_EIIB_TYPE_1_CYS. 1 hit.
PS51103. PTS_EIIC_TYPE_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Identification of genes subject to positive selection in uropathogenic strains of Escherichia coli: a comparative genomics approach."
    Chen S.L., Hung C.-S., Xu J., Reigstad C.S., Magrini V., Sabo A., Blasiar D., Bieri T., Meyer R.R., Ozersky P., Armstrong J.R., Fulton R.S., Latreille J.P., Spieth J., Hooton T.M., Mardis E.R., Hultgren S.J., Gordon J.I.
    Proc. Natl. Acad. Sci. U.S.A. 103:5977-5982(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: UTI89 / UPECImported.

Entry informationi

Entry nameiQ1R498_ECOUT
AccessioniPrimary (citable) accession number: Q1R498
Entry historyi
Integrated into UniProtKB/TrEMBL: May 16, 2006
Last sequence update: May 16, 2006
Last modified: April 1, 2015
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.