Q1R1M8 (Q1R1M8_CHRSD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
3-deoxy-D-manno-octulosonic acid kinase HAMAP-Rule MF_00521
Short name=Kdo kinase HAMAP-Rule MF_00521
EC=2.7.1.166 HAMAP-Rule MF_00521

Gene names

Name:	kdkA HAMAP-Rule MF_00521
Ordered Locus Names:	Csal_0015

Organism

Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768) [Complete proteome] [HAMAP] EMBL ABE57380.1

Taxonomic identifier

290398 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Halomonadaceae › Chromohalobacter › Chromohalobacter salexigens

Protein attributes

Sequence length	239 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position By similarity. HAMAP-Rule MF_00521
Catalytic activity	Alpha-Kdo-(2->6)-lipid IV(A) + ATP = 4-O-phospho-alpha-Kdo-(2->6)-lipid IV(A) + ADP. HAMAP-Rule MF_00521
Pathway	Bacterial outer membrane biogenesis; LPS core biosynthesis. HAMAP-Rule MF_00521
Subcellular location	Cell inner membrane; Peripheral membrane protein; Cytoplasmic side By similarity HAMAP-Rule MF_00521.
Sequence similarities	Belongs to the protein kinase superfamily. KdkA/RfaP family. HAMAP-Rule MF_00521

Ontologies

Keywords
Biological process	Lipopolysaccharide biosynthesis HAMAP-Rule MF_00521
Cellular component	Cell inner membrane HAMAP-Rule MF_00521 Cell membrane Membrane
Ligand	ATP-binding HAMAP-Rule MF_00521 Nucleotide-binding
Molecular function	Kinase HAMAP-Rule MF_00521 EMBL ABE57380.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	lipopolysaccharide core region biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Cellular_component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP kinase activity Inferred from electronic annotation. Source: UniProtKB-KW phosphotransferase activity, alcohol group as acceptor Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	170	1	By similarity HAMAP-Rule MF_00521

Sequences

	Sequence		Length	Mass (Da)
	Q1R1M8 [UniParc]. Last modified May 16, 2006. Version 1. Checksum: C8E6C44D498B9C04	FASTA	239	26,808
	10 20 30 40 50 60 MATFQTGKAF ILYDADILCD AGQGPQIDAD WFTPAFWRSR DAVIGEAPGR GASLFVAHGD 70 80 90 100 110 120 ERWALRPYRR GGAIARVSER RYVWTGLERT RAFREMRLTA ALEQRGLPVP TPVAAAVWRH 130 140 150 160 170 180 ALSYEAALIT RVIPGVQALA ERLPTADTPL LARVGQTIRR FHDVGLDHVD LNARNLLVDA 190 200 210 220 230 DDRVWLIDLD RCRLRAPGRW QEANLARLER SLARFSPTTA GRAFTAIVDG YRHAPRDSR

References

[1]

"Complete sequence of Chromohalobacter salexigens DSM 3043." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Saunders E., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Csonka L.N., O'Conner K., Vreeland R.H., Oren A., Vargas C., Nieto J., Arahal D.R., Goodner B., Wheeler C., Hall P., Ewing A., Benson L., McBeath D., Canovas D., Richardson P. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 3043 / ATCC BAA-138 / NCIMB 13768.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000285 Genomic DNA. Translation: ABE57380.1.
RefSeq	YP_572079.1. NC_007963.1.
3D structure databases
ProteinModelPortal	Q1R1M8.
ModBase	Search...
Protein-protein interaction databases
STRING	290398.Csal_0015.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABE57380; ABE57380; Csal_0015.
GeneID	4027334.
KEGG	csa:Csal_0015.
PATRIC	21443712. VBIChrSal113723_0015.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0515.
HOGENOM	HOG000269423.
KO	K11211.
OMA	VYHADLN.
ProtClustDB	PRK01723.
Enzyme and pathway databases
UniPathway	UPA00958.
Family and domain databases
HAMAP	MF_00521. KDO_kinase.
InterPro	IPR022826. KDO_kinase. IPR011009. Kinase-like_dom. IPR010440. LipoPS_kinase. [Graphical view]
Pfam	PF06293. Kdo. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q1R1M8_CHRSD

Accession

Primary (citable) accession number: Q1R1M8

Entry history

Integrated into UniProtKB/TrEMBL:	May 16, 2006
Last sequence update:	May 16, 2006
Last modified:	May 1, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)