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Q1QZZ4 (SYR_CHRSD) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:Csal_0602
OrganismChromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768) [Complete proteome] [HAMAP]
Taxonomic identifier290398 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesHalomonadaceaeChromohalobacter

Protein attributes

Sequence length561 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 561561Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000018013

Regions

Motif128 – 13811"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q1QZZ4 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: 9FDFD1863ABBEA80

FASTA56161,535
        10         20         30         40         50         60 
MKETIIELLE AAGTQLKQQG ILPADAPLTV KVEPTKDKAH GDYASNLALT LAKPAGRKPR 

        70         80         90        100        110        120 
DLAEALVAAL PPSDAIRQVD IAGPGFINFF AATDAAAQVV PAILDAGDTF GRSLSGAGEK 

       130        140        150        160        170        180 
VQVEFVSANP TGPLHVGHGR GAAIGDCLCR LLEATGFEVT REFYYNDAGA QIQNLALSVQ 

       190        200        210        220        230        240 
ARVQGLTPDD AAWPEDGYRG AYINDVAQAY LAGETVVADD RDVTASAAPD DLDAIRDFAV 

       250        260        270        280        290        300 
AYLRREQDLD LKAFGVAFDV YFLESSLYDD GKVDATVKAL VEGGHTYEED GATWLRTTDF 

       310        320        330        340        350        360 
GDDKDRVMRK KDGGYTYFLP DVAYHLDKWQ RGFTTVINEQ GADHHSTVTR VRAGLQALEA 

       370        380        390        400        410        420 
GIPQGWPDYV LHQMVLVTRS GVEVKLSKRA GSYVTLRDLI DEVGRDATRF FLAARRSDSQ 

       430        440        450        460        470        480 
LTFDIDLARS QSNDNPVYYI QYAHARVCSV MRRAQDAGKA FDRDLAMQHL GRLDAPQEKE 

       490        500        510        520        530        540 
LMNRLARYPE VVERAARMRE PQQVAQYLMD LAADFHTCYN AVKVMVEDDE LRNARLALGL 

       550        560 
ATRQVIRNGL DLMGVSAPEE M 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000285 Genomic DNA. Translation: ABE57964.1.
RefSeqYP_572663.1. NC_007963.1.

3D structure databases

ProteinModelPortalQ1QZZ4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING290398.Csal_0602.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE57964; ABE57964; Csal_0602.
GeneID4026261.
KEGGcsa:Csal_0602.
PATRIC21444956. VBIChrSal113723_0618.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMAMEHMGFG.
OrthoDBEOG6JB13C.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_CHRSD
AccessionPrimary (citable) accession number: Q1QZZ4
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 16, 2006
Last modified: May 14, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries