ID   APAH_CHRSD              Reviewed;         272 AA.
AC   Q1QZ29;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2006, sequence version 1.
DT   16-JUN-2009, entry version 19.
DE   RecName: Full=Bis(5'-nucleosyl)-tetraphosphatase, symmetrical;
DE            EC=3.6.1.41;
DE   AltName: Full=Diadenosine tetraphosphatase;
DE   AltName: Full=Ap4A hydrolase;
DE   AltName: Full=Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase;
GN   Name=apaH; OrderedLocusNames=Csal_0922;
OS   Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB
OS   13768).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Oceanospirillales;
OC   Halomonadaceae; Chromohalobacter.
OX   NCBI_TaxID=290398;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T.,
RA   Bruce D., Han C., Tapia R., Gilna P., Saunders E., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Csonka L.N.,
RA   O'Conner K., Vreeland R.H., Oren A., Vargas C., Nieto J., Arahal D.R.,
RA   Goodner B., Wheeler C., Hall P., Ewing A., Benson L., McBeath D.,
RA   Canovas D., Richardson P.;
RT   "Complete sequence of Chromohalobacter salexigens DSM 3043.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to
CC       yield ADP (By similarity).
CC   -!- CATALYTIC ACTIVITY: P(1),P(4)-bis(5'-adenosyl) tetraphosphate +
CC       H(2)O = 2 ADP.
CC   -!- SIMILARITY: Belongs to the Ap4A hydrolase family.
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DR   EMBL; CP000285; ABE58279.1; -; Genomic_DNA.
DR   RefSeq; YP_572978.1; -.
DR   GeneID; 4027429; -.
DR   GenomeReviews; CP000285_GR; Csal_0922.
DR   KEGG; csa:Csal_0922; -.
DR   NMPDR; fig|290398.4.peg.914; -.
DR   HOGENOM; Q1QZ29; -.
DR   OMA; Q1QZ29; LVFGHWA.
DR   BioCyc; CSAL290398:CSAL_0922-MON; -.
DR   GO; GO:0008803; F:bis(5'-nucleosyl)-tetraphosphatase (symmetr...; IEA:HAMAP.
DR   HAMAP; MF_00199; -; 1.
DR   InterPro; IPR004617; ApaH.
DR   InterPro; IPR004843; M-pesterase.
DR   Pfam; PF00149; Metallophos; 1.
DR   PIRSF; PIRSF000903; B5n-ttraPtase_sm; 1.
DR   TIGRFAMs; TIGR00668; apaH; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase.
FT   CHAIN         1    272       Bis(5'-nucleosyl)-tetraphosphatase,
FT                                symmetrical.
FT                                /FTId=PRO_1000012053.
SQ   SEQUENCE   272 AA;  29679 MW;  F7989695BBE54BAD CRC64;
     MSTYAIGDLQ GCHAEFEALL ERIAFEPRRD RLWLVGDLVN RGPGSLACLR AVKALGDSAR
     VVLGNHDLHL LAAAWAGAPL KRSDTLAPIL EADDRDELLD WLRRQPLLVR DDELDAVMTH
     AGLPPHWSVT QAAEHAAEVE RALRGEAVGD FLAAMYGNSP ARWTDELEGI DRLRVIVNTF
     TRMRFIAADG TLDFAAKEGL DSAPEGFAPW FTYARDDDPR IVFGHWAALQ GATPGARVRA
     LALDTGCVWG GALTALDLVS GEYHVEPAHA SR
//