Reviewed, UniProtKB/Swiss-Prot Q1QZ29 (APAH_CHRSD)

Names and origin

Protein names

Recommended name:
    Bis(5'-nucleosyl)-tetraphosphatase, symmetrical
    EC=3.6.1.41
Alternative name(s):
    Diadenosine tetraphosphatase
    Ap4A hydrolase
    Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase

Gene names

Name:	apaH
Ordered Locus Names:	Csal_0922

Organism

Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768) [Complete proteome] [HAMAP]

Taxonomic identifier

290398 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Halomonadaceae › Chromohalobacter

Protein attributes

Sequence length	272 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP By similarity.
Catalytic activity	P1,P(4)-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP. HAMAP MF_00199
Sequence similarities	Belongs to the Ap4A hydrolase family.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 272	272	Bis(5'-nucleosyl)-tetraphosphatase, symmetrical HAMAP MF_00199		PRO_1000012053

Sequences

	Sequence		Length	Mass (Da)
	Q1QZ29-1 [UniParc]. Last modified May 16, 2006. Version 1. Checksum: F7989695BBE54BAD	FASTA	272	29,679
	10 20 30 40 50 60 MSTYAIGDLQ GCHAEFEALL ERIAFEPRRD RLWLVGDLVN RGPGSLACLR AVKALGDSAR 70 80 90 100 110 120 VVLGNHDLHL LAAAWAGAPL KRSDTLAPIL EADDRDELLD WLRRQPLLVR DDELDAVMTH 130 140 150 160 170 180 AGLPPHWSVT QAAEHAAEVE RALRGEAVGD FLAAMYGNSP ARWTDELEGI DRLRVIVNTF 190 200 210 220 230 240 TRMRFIAADG TLDFAAKEGL DSAPEGFAPW FTYARDDDPR IVFGHWAALQ GATPGARVRA 250 260 270 LALDTGCVWG GALTALDLVS GEYHVEPAHA SR

References

[1]

"Complete sequence of Chromohalobacter salexigens DSM 3043." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Saunders E., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Csonka L.N., O'Conner K., Vreeland R.H., Oren A., Vargas C., Nieto J., Arahal D.R., Goodner B., Wheeler C., Hall P., Ewing A., Benson L., McBeath D., Canovas D., Richardson P. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000285 Genomic DNA. Translation: ABE58279.1.
RefSeq	YP_572978.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4027429.
GenomeReviews	Gene locus Csal_0922 in contig CP000285_GR.
KEGG	csa:Csal_0922.
NMPDR	fig|290398.4.peg.914.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q1QZ29.
OMA	Q1QZ29. LVFGHWA.
Enzyme and pathway databases
BioCyc	CSAL290398:CSAL_0922-MON.
Family and domain databases
HAMAP	MF_00199. [Tree]
InterPro	IPR004617. ApaH. IPR004843. M-pesterase. [Graphical view]
Pfam	PF00149. Metallophos. 1 hit. [Graphical view]
PIRSF	PIRSF000903. B5n-ttraPtase_sm. 1 hit.
TIGRFAMs	TIGR00668. apaH. 1 hit.
ProtoNet	Search...

Entry information

Entry name

APAH_CHRSD

Accession

Primary (citable) accession number: Q1QZ29

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	May 16, 2006
Last modified:	June 16, 2009
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)