Reviewed, UniProtKB/Swiss-Prot Q1QZ19 (G6PI1_CHRSD)

Names and origin

Protein names

Recommended name:
    Glucose-6-phosphate isomerase 1
      Short name=GPI 1
    EC=5.3.1.9
Alternative name(s):
    Phosphoglucose isomerase 1
      Short name=PGI 1
    Phosphohexose isomerase 1
      Short name=PHI 1

Gene names

Name:	pgi1
Ordered Locus Names:	Csal_0932

Organism

Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768) [Complete proteome] [HAMAP]

Taxonomic identifier

290398 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Halomonadaceae › Chromohalobacter

Protein attributes

Sequence length	548 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP MF_00473
Pathway	Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP MF_00473
Subcellular location	Cytoplasm By similarity HAMAP MF_00473.
Sequence similarities	Belongs to the GPI family.

Ontologies

Keywords
Biological process	Gluconeogenesis Glycolysis
Cellular component	Cytoplasm
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: HAMAP glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glucose-6-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 548	548	Glucose-6-phosphate isomerase 1 HAMAP MF_00473		PRO_0000252615
Sites
	Active site	353	1	Proton donor By similarity
	Active site	384	1	By similarity
	Active site	495	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q1QZ19-1 [UniParc]. Last modified May 16, 2006. Version 1. Checksum: 6B3402F328E242F9	FASTA	548	61,466
	10 20 30 40 50 60 MFQLTRSVTW RALERLKQET FDDRISDYFA ADPQRFEKMS LRVGGLFLDY SKHHVSDAVL 70 80 90 100 110 120 AKLIELADHS ALVQRRAQMF SGDIINVTED RPVLHTALRH LGDEPVYADG KDVMPEIQST 130 140 150 160 170 180 REQIKRFSEA VRSGEWKGYS GERIKDVVNI GIGGSDLGPN MACRALLKYR HPELNFHFVS 190 200 210 220 230 240 NVDGTHIQKV LQRLDPATTL FIVSTKTFST QETLLNAKTA RRWFLDNAGE DADVGAHFIA 250 260 270 280 290 300 ASTNRKAAME FGIREENVFE FWAWVGGRYS MWSSIGLPIA LSIGFDGFME LLEGAHEMDR 310 320 330 340 350 360 HFIEAPFAEN MPVLMALIGI WYINFIGAET HAIVPYDQAL HQLPSFLQQL DMESNGKSVD 370 380 390 400 410 420 IFDQPVNYKT GPIVWGQTGS NGQHAFFQLL HQGTRYVPID FIASLKPEPG FEDHHFALLT 430 440 450 460 470 480 NMLAQANAFM EGSQDGSQLD PYSCPGNRPS STLLLDELTP RNLGALIALY EHKVFVQGVI 490 500 510 520 530 540 WNINSFDQWG VQLGKRIAGE ISERIDTNVG DFDASTQGLL SLVREYFPAS TPDAKASDNN KKSRGKTS

References

[1]

"Complete sequence of Chromohalobacter salexigens DSM 3043." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Saunders E., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Csonka L.N., O'Conner K., Vreeland R.H., Oren A., Vargas C., Nieto J., Arahal D.R., Goodner B., Wheeler C., Hall P., Ewing A., Benson L., McBeath D., Canovas D., Richardson P. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000285 Genomic DNA. Translation: ABE58289.1.
RefSeq	YP_572988.1.
3D structure databases
HSSP	HSSP built from PDB template 2CXN based on UniProtKB Q3TEE7.
SMR	Q1QZ19. Positions 2-526.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1QZ19.
Genome annotation databases
GeneID	4026786.
GenomeReviews	Gene locus Csal_0932 in contig CP000285_GR.
KEGG	csa:Csal_0932.
NMPDR	fig|290398.4.peg.922.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0166.
HOGENOM	HBG352954.
OMA	GPKIVSQ.
Enzyme and pathway databases
BioCyc	CSAL290398:CSAL_0932-MONOMER.
Family and domain databases
HAMAP	MF_00473. G6P_isomerase. [Tree]
InterPro	IPR001672. G6P_Isomerase. IPR018189. Phosphoglucose_isomerase_CS. [Graphical view]
PANTHER	PTHR11469. G6P_Isomerase. 1 hit.
Pfam	PF00342. PGI. 1 hit. [Graphical view]
PRINTS	PR00662. G6PISOMERASE.
PROSITE	PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit. PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit. PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G6PI1_CHRSD

Accession

Primary (citable) accession number: Q1QZ19

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 17, 2006
Last sequence update:	May 16, 2006
Last modified:	January 19, 2010
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)