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Protein

Glucose-6-phosphate isomerase 1

Gene

pgi1

Organism
Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase 1 (pgi1), Glucose-6-phosphate isomerase 2 (pgi2)
  3. Pyrophosphate--fructose 6-phosphate 1-phosphotransferase (pfp)
  4. Fructose-1,6-bisphosphate aldolase (Csal_0370)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei353Proton donorUniRule annotation1
Active sitei384UniRule annotation1
Active sitei495UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciCSAL290398:G1GJB-966-MONOMER
UniPathwayiUPA00109; UER00181

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase 1UniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPI 1UniRule annotation
Alternative name(s):
Phosphoglucose isomerase 1UniRule annotation
Short name:
PGI 1UniRule annotation
Phosphohexose isomerase 1UniRule annotation
Short name:
PHI 1UniRule annotation
Gene namesi
Name:pgi1UniRule annotation
Ordered Locus Names:Csal_0932
OrganismiChromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768)
Taxonomic identifieri290398 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesHalomonadaceaeChromohalobacter
Proteomesi
  • UP000000239 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002526151 – 548Glucose-6-phosphate isomerase 1Add BLAST548

Proteomic databases

PRIDEiQ1QZ19

Interactioni

Protein-protein interaction databases

STRINGi290398.Csal_0932

Structurei

3D structure databases

ProteinModelPortaliQ1QZ19
SMRiQ1QZ19
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QP8 Bacteria
COG0166 LUCA
HOGENOMiHOG000261370
KOiK01810
OMAiTNSQHAF
OrthoDBiPOG091H04C3

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
Gene3Di1.10.1390.10, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR023096 G6P_Isomerase_C
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q1QZ19-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFQLTRSVTW RALERLKQET FDDRISDYFA ADPQRFEKMS LRVGGLFLDY
60 70 80 90 100
SKHHVSDAVL AKLIELADHS ALVQRRAQMF SGDIINVTED RPVLHTALRH
110 120 130 140 150
LGDEPVYADG KDVMPEIQST REQIKRFSEA VRSGEWKGYS GERIKDVVNI
160 170 180 190 200
GIGGSDLGPN MACRALLKYR HPELNFHFVS NVDGTHIQKV LQRLDPATTL
210 220 230 240 250
FIVSTKTFST QETLLNAKTA RRWFLDNAGE DADVGAHFIA ASTNRKAAME
260 270 280 290 300
FGIREENVFE FWAWVGGRYS MWSSIGLPIA LSIGFDGFME LLEGAHEMDR
310 320 330 340 350
HFIEAPFAEN MPVLMALIGI WYINFIGAET HAIVPYDQAL HQLPSFLQQL
360 370 380 390 400
DMESNGKSVD IFDQPVNYKT GPIVWGQTGS NGQHAFFQLL HQGTRYVPID
410 420 430 440 450
FIASLKPEPG FEDHHFALLT NMLAQANAFM EGSQDGSQLD PYSCPGNRPS
460 470 480 490 500
STLLLDELTP RNLGALIALY EHKVFVQGVI WNINSFDQWG VQLGKRIAGE
510 520 530 540
ISERIDTNVG DFDASTQGLL SLVREYFPAS TPDAKASDNN KKSRGKTS
Length:548
Mass (Da):61,466
Last modified:May 16, 2006 - v1
Checksum:i6B3402F328E242F9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000285 Genomic DNA Translation: ABE58289.1
RefSeqiWP_011506235.1, NC_007963.1

Genome annotation databases

EnsemblBacteriaiABE58289; ABE58289; Csal_0932
KEGGicsa:Csal_0932

Similar proteinsi

Entry informationi

Entry nameiG6PI1_CHRSD
AccessioniPrimary (citable) accession number: Q1QZ19
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: May 16, 2006
Last modified: June 20, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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