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Q1QZ10

- PNCB_CHRSD

UniProt

Q1QZ10 - PNCB_CHRSD

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Protein

Nicotinate phosphoribosyltransferase

Gene

pncB

Organism
Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.UniRule annotation

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ligase activity Source: UniProtKB-KW
  2. nicotinate-nucleotide diphosphorylase (carboxylating) activity Source: InterPro
  3. nicotinate phosphoribosyltransferase activity Source: InterPro

GO - Biological processi

  1. NAD biosynthetic process Source: UniProtKB-UniPathway
  2. nicotinate nucleotide biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase, Transferase

Keywords - Biological processi

Pyridine nucleotide biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00253; UER00457.

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferaseUniRule annotation (EC:6.3.4.21UniRule annotation)
Short name:
NAPRTaseUniRule annotation
Gene namesi
Name:pncBUniRule annotation
Ordered Locus Names:Csal_0941
OrganismiChromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768)
Taxonomic identifieri290398 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesHalomonadaceaeChromohalobacter
ProteomesiUP000000239: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 390390Nicotinate phosphoribosyltransferasePRO_1000146838Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi290398.Csal_0941.

Structurei

3D structure databases

ProteinModelPortaliQ1QZ10.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1488.
HOGENOMiHOG000284928.
KOiK00763.
OMAiQAVFHRY.
OrthoDBiEOG6X10XB.

Family and domain databases

HAMAPiMF_00570. NAPRTase.
InterProiIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERiPTHR11098. PTHR11098. 1 hit.
PfamiPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFiPIRSF000484. NAPRT. 1 hit.
SUPFAMiSSF51690. SSF51690. 1 hit.
TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1QZ10-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLDSLLDNDF YKFTMQSAVI KRFPYARARY AFINRGEHAF PPGFGEQLRE
60 70 80 90 100
AVDAMADLSL SVEEKRFLER TCPYLDPTYL DFLSGFRYDP SEVDIVQQGE
110 120 130 140 150
RFELRIEGLW YRTILWEVPL MALISEIWYR MGDGKRDADA IIDMRTRDKI
160 170 180 190 200
EHYKRLGLKI AEFGTRRRYS YDVHDRVVAS LRHHGGDTFS GSSNVHLAMR
210 220 230 240 250
HGVKPIGTHA HEWFMFHGAR FGFKMANSLA LEHWVDVYRG DLGIALTDTF
260 270 280 290 300
TSATFFDSFD KKFAKLFDGV RHDSGDPLEF AAATIAHYER MGIDPRTKTI
310 320 330 340 350
IFSDALTPER VERIDAFCRG RITTAFGIGT NFTNDVGVTP MNMVIKMTEA
360 370 380 390
RPEGQHWMPV IKLSDVPDKN TGDPDMIELA KRVLALSRRA
Length:390
Mass (Da):44,776
Last modified:May 16, 2006 - v1
Checksum:i7E8938436BD7ACE4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000285 Genomic DNA. Translation: ABE58298.1.
RefSeqiWP_011506244.1. NC_007963.1.
YP_572997.1. NC_007963.1.

Genome annotation databases

EnsemblBacteriaiABE58298; ABE58298; Csal_0941.
GeneIDi4026795.
KEGGicsa:Csal_0941.
PATRICi21445666. VBIChrSal113723_0959.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000285 Genomic DNA. Translation: ABE58298.1 .
RefSeqi WP_011506244.1. NC_007963.1.
YP_572997.1. NC_007963.1.

3D structure databases

ProteinModelPortali Q1QZ10.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 290398.Csal_0941.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABE58298 ; ABE58298 ; Csal_0941 .
GeneIDi 4026795.
KEGGi csa:Csal_0941.
PATRICi 21445666. VBIChrSal113723_0959.

Phylogenomic databases

eggNOGi COG1488.
HOGENOMi HOG000284928.
KOi K00763.
OMAi QAVFHRY.
OrthoDBi EOG6X10XB.

Enzyme and pathway databases

UniPathwayi UPA00253 ; UER00457 .

Family and domain databases

HAMAPi MF_00570. NAPRTase.
InterProi IPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view ]
PANTHERi PTHR11098. PTHR11098. 1 hit.
Pfami PF04095. NAPRTase. 1 hit.
[Graphical view ]
PIRSFi PIRSF000484. NAPRT. 1 hit.
SUPFAMi SSF51690. SSF51690. 1 hit.
TIGRFAMsi TIGR01514. NAPRTase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 3043 / ATCC BAA-138 / NCIMB 13768.

Entry informationi

Entry nameiPNCB_CHRSD
AccessioniPrimary (citable) accession number: Q1QZ10
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 16, 2006
Last modified: October 1, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3